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A0RBL1 (A0RBL1_BACAH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ketol-acid reductoisomerase 1 HAMAP MF_00435
EC=1.1.1.86 HAMAP MF_00435
Alternative name(s):
Acetohydroxy-acid isomeroreductase 1 HAMAP MF_00435
Alpha-keto-beta-hydroxylacil reductoisomerase 1 HAMAP MF_00435
Gene names
Name:ilvC1 HAMAP MF_00435
Ordered Locus Names:BALH_1254
OrganismBacillus thuringiensis (strain Al Hakam) [Complete proteome] [HAMAP]
Taxonomic identifier412694 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length338 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP+ = (S)-2-hydroxy-2-ethyl-3-oxobutanoate + NADPH. HAMAP MF_00435

(R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH. HAMAP MF_00435

Pathway

Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4. HAMAP MF_00435

Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4. HAMAP MF_00435

Sequence similarities

Belongs to the ketol-acid reductoisomerase family. HAMAP MF_00435

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1091 By similarity HAMAP MF_00435

Sequences

Sequence LengthMass (Da)Tools
A0RBL1 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: E4D665461FFBBF7C

FASTA33836,910
        10         20         30         40         50         60 
MKMAKVYYEK DVTVNVLKEK KVAIIGYGSQ GHAHAQNLRD NGFDVVVGLR KGKSWDKAKE 

        70         80         90        100        110        120 
DGFSVYTVAE AAKQADVVMI LLPDELQPEV YEAEIAPNLQ AGNSLVFAHG FNVHFDQVKP 

       130        140        150        160        170        180 
PANVDVFLVA PKGPGHLVRR TFSEGGAVPA LFAVYQDATG VATEKALSYA DGIGATRAGV 

       190        200        210        220        230        240 
LETTFKEETE TDLFGEQAVL CGGVTALVKA GFETLVDAGY QPELAYFECL HELKLIVDLM 

       250        260        270        280        290        300 
YEGGLENMRY SVSDTAQWGD FVSGPRVVTE DTKKAMGAVL AEIQDGTFAR GWIAEHKAGR 

       310        320        330 
PNFHATNEKE NEHEIEVVGR KLREMMPFVQ PRVKAGVK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000485 Genomic DNA. Translation: ABK84604.1.
RefSeqYP_894111.1. NC_008600.1.

3D structure databases

ProteinModelPortalA0RBL1.
SMRA0RBL1. Positions 5-329.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0RBL1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000069730; EBBACP00000067967; EBBACG00000069721.
GeneID4543638.
GenomeReviewsGene locus BALH_1254 in contig CP000485_GR.
KEGGbtl:BALH_1254.
PATRIC18994906. VBIBacThu63319_1456.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0059.
GeneTreeEBGT00050000000943.
HOGENOMHBG286525.
OMAEYANGRG.
ProtClustDBPRK05479.

Family and domain databases

HAMAPMF_00435. IlvC.
[Tree]
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013023. AcH_isomrdctse.
IPR000506. AcH_isomrdctse_C.
IPR013328. DH_multihelical.
IPR013116. IlvN.
[Graphical view]
Gene3DG3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00053.
PANTHERPTHR21371. AcH_isomrdctse. 1 hit.
PfamPF01450. IlvC. 1 hit.
PF07991. IlvN. 1 hit.
[Graphical view]
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMsTIGR00465. IlvC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA0RBL1_BACAH
AccessionPrimary (citable) accession number: A0RBL1
Entry history
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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