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A0RBJ8 (UPPP3_BACAH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 3

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 3
Undecaprenyl pyrophosphate phosphatase 3
Gene names
Name:uppP3
Ordered Locus Names:BALH_1240
OrganismBacillus thuringiensis (strain Al Hakam) [Complete proteome] [HAMAP]
Taxonomic identifier412694 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length254 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence caution

The sequence ABK84591.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 254254Undecaprenyl-diphosphatase 3 HAMAP-Rule MF_01006
PRO_0000290686

Regions

Transmembrane8 – 2821Helical; Potential
Transmembrane33 – 5321Helical; Potential
Transmembrane74 – 9421Helical; Potential
Transmembrane97 – 11721Helical; Potential
Transmembrane133 – 15321Helical; Potential
Transmembrane174 – 19421Helical; Potential
Transmembrane207 – 22721Helical; Potential
Transmembrane233 – 25321Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A0RBJ8 [UniParc].

Last modified June 12, 2007. Version 2.
Checksum: 9C71CC091AF28D5A

FASTA25427,350
        10         20         30         40         50         60 
MGAVEGLTEF LPVSSTGHMI LTGHLIGFDD DRAKVFEVVI QLGSILAVVV IFWKRLWSLV 

        70         80         90        100        110        120 
GIGKVTDGPS LNLLHIIIGM IPAGVLGVLF HSAIKEVLFG PGPVVISLVA GGILMIVAEK 

       130        140        150        160        170        180 
FSKPSTARTL DEITYKQAFT IGMFQCLALW PGFSRSGSTI SGGLLARVSH TAAAEYTFIL 

       190        200        210        220        230        240 
AVPMMVAASG LDLIKSWDIL STADIPLFAT GFITAFVVAM LAIVSFLKLL SRVKLTPFAY 

       250 
YRFILAAVFY FFIM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000485 Genomic DNA. Translation: ABK84591.1. Different initiation.
RefSeqYP_894098.1. NC_008600.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING412694.BALH_1240.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK84591; ABK84591; BALH_1240.
GeneID4545275.
KEGGbtl:BALH_1240.
PATRIC18994874. VBIBacThu63319_1440.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycBTHU412694:GH1W-1283-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP3_BACAH
AccessionPrimary (citable) accession number: A0RBJ8
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: June 12, 2007
Last modified: February 19, 2014
This is version 54 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families