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A0RB32 (PRPE_BACAH) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Bis(5'-nucleosyl)-tetraphosphatase prpE [asymmetrical]

EC=3.6.1.17
Alternative name(s):
Ap4A hydrolase
Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase
Short name=Diadenosine tetraphosphatase
Gene names
Name:prpE
Ordered Locus Names:BALH_1064
OrganismBacillus thuringiensis (strain Al Hakam) [Complete proteome] [HAMAP]
Taxonomic identifier412694 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length246 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Asymmetrically hydrolyzes Ap4p to yield AMP and ATP By similarity. HAMAP MF_01443

Catalytic activity

P1,P(4)-bis(5'-guanosyl) tetraphosphate + H2O = GTP + GMP. HAMAP MF_01443

Cofactor

Nickel By similarity. HAMAP MF_01443

Sequence similarities

Belongs to the prpE family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 246246Bis(5'-nucleosyl)-tetraphosphatase prpE [asymmetrical] HAMAP MF_01443
PRO_0000297701

Sequences

Sequence LengthMass (Da)Tools
A0RB32 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: 18DDDC38A32233E8

FASTA24628,241
        10         20         30         40         50         60 
MKYDIIGDIH GCLQEFQNLT EKLGYNWSSG LPVHPDQRKL AFVGDITDRG PHSLRMIEIV 

        70         80         90        100        110        120 
WELVIHKKEA YYAPGNHCNK LYRFFLGRNV TVAHGLETTV AEYEALPSHK QNMIKEKFIT 

       130        140        150        160        170        180 
LYEQSPLYHV LDEKRLLVCH AGIRQDYIGR QDKKVQTFVL YGDITGEKHA DGSPVRRDWA 

       190        200        210        220        230        240 
KEYKGTAWIV YGHTPVKEPR FVNHTVNIDT GAVFGGRLTA LRYPEMETVS VPSSLPFVPE 


KFRPIS 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000485 Genomic DNA. Translation: ABK84425.1.
RefSeqYP_893932.1. NC_008600.1.

3D structure databases

ProteinModelPortalA0RB32.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0RB32.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000071149; EBBACP00000069386; EBBACG00000071140.
GeneID4546512.
GenomeReviewsGene locus BALH_1064 in contig CP000485_GR.
KEGGbtl:BALH_1064.
NMPDRfig|412694.5.peg.1075.
PATRIC18994470. VBIBacThu63319_1239.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0639.
GeneTreeEBGT00050000002430.
HOGENOMHBG724457.
OMAYVPGNHC.
ProtClustDBPRK13625.

Enzyme and pathway databases

BioCycBTHU412694:BALH_1064-MONOMER.

Family and domain databases

HAMAPMF_01443. PrpE.
[Tree]
InterProIPR023937. Bis(5'-nucleosyl)-tetraP_PrpE.
IPR004843. Metallo_PEstase_dom.
[Graphical view]
KOK01090.
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePRPE_BACAH
AccessionPrimary (citable) accession number: A0RB32
Entry history
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: January 9, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families