Reviewed,
UniProtKB/Swiss-Prot A0RB32 (PRPE_BACAH)
Last modified
June 15, 2010.
Version 21.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
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Names and originHide
| Protein names | Recommended name: Bis(5'-nucleosyl)-tetraphosphatase prpE [asymmetrical] EC=3.6.1.17 Alternative name(s): Ap4A hydrolase Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase Short name=Diadenosine tetraphosphatase | ||||
| Gene names |
| ||||
| Organism | Bacillus thuringiensis (strain Al Hakam) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 412694 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group |
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Protein attributesHide
| Sequence length | 246 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
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General annotation (Comments)Hide
| Function | Asymmetrically hydrolyzes Ap4p to yield AMP and ATP By similarity. HAMAP MF_01443 |
| Catalytic activity | P1,P(4)-bis(5'-guanosyl) tetraphosphate + H2O = GTP + GMP. HAMAP MF_01443 |
| Cofactor | Nickel By similarity. HAMAP MF_01443 |
| Sequence similarities | Belongs to the prpE family. |
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OntologiesHide
| Keywords | |
|---|---|
| Ligand | GTP-binding Nickel Nucleotide-binding |
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Molecular function | GTP binding Inferred from electronic annotation. Source: UniProtKB-KW bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activityInferred from electronic annotation. Source: HAMAP nickel ion bindingInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
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Sequence annotation (Features)Hide
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 246 | 246 | Bis(5'-nucleosyl)-tetraphosphatase prpE [asymmetrical] HAMAP MF_01443 | PRO_0000297701 | |||
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SequencesHide
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ReferencesHide
| [1] | "The complete genome sequence of Bacillus thuringiensis Al Hakam." Challacombe J.F., Altherr M.R., Xie G., Bhotika S.S., Brown N., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Green L.D., Han C.S. Brettin T.S.J. Bacteriol. 189:3680-3681(2007) [PubMed: 17337577] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
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Cross-referencesHide
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000485 Genomic DNA. Translation: ABK84425.1. |
| RefSeq | YP_893932.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A0RB32. |
Genome annotation databases | |
| EnsemblBacteria | EBBACT00000071149; EBBACP00000069386; EBBACG00000071140. |
| GeneID | 4546512. |
| GenomeReviews | Gene locus BALH_1064 in contig CP000485_GR. |
| KEGG | btl:BALH_1064. |
| NMPDR | fig|412694.5.peg.1075. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0639. |
| HOGENOM | HBG724457. |
| OMA | HCNKLYR. |
| ProtClustDB | PRK13625. |
Family and domain databases | |
| HAMAP | MF_01443. PrpE. [Tree] |
| InterPro | IPR004843. M-pesterase. [Graphical view] |
| Pfam | PF00149. Metallophos. 1 hit. [Graphical view] |
| ProtoNet | Search... |
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Entry informationHide
| Entry name | PRPE_BACAH | ||||||||
| Accession | Primary (citable) accession number: A0RB32 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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