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A0RAS4 (A0RAS4_BACAH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase 1 HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase 1 HAMAP MF_00323
Protoheme ferro-lyase 1 HAMAP MF_00323
Gene names
Name:hemH1 HAMAP MF_00323
Ordered Locus Names:BALH_0951
OrganismBacillus thuringiensis (strain Al Hakam) [Complete proteome] [HAMAP]
Taxonomic identifier412694 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length311 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1821Iron By similarity HAMAP MF_00323
Metal binding2631Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A0RAS4 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: 17900ED592BD3020

FASTA31135,344
        10         20         30         40         50         60 
MKKKIGLLVM AYGTPYKEED IERYYTHIRR GRKPSPEMLE DLTERYRAIG GISPLATITL 

        70         80         90        100        110        120 
EQAKKLEKRL NEVQDEVEYH MYLGLKHIEP FIEDAVKDMH NDGIQDAIAL VLAPHYSTFS 

       130        140        150        160        170        180 
VKSYVGRAQE EAEKLGNLTI HGIDSWYKEP KFIQYWVDAV KGIYNGMSEA EREKAVLIVS 

       190        200        210        220        230        240 
AHSLPEKIIA MGDPYPDQLN ETADYIARGA EVANYAVGWQ SAGNTPDPWI GPDVQDLTRE 

       250        260        270        280        290        300 
LNEKYGYTSF VYAPVGFVAE HLEVLYDNDF ECKVVTDEIG AKYYRPEMPN ASDAFIDSLT 

       310 
DVVLKKKESV M

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000485 Genomic DNA. Translation: ABK84317.1.
RefSeqYP_893824.1. NC_008600.1.

3D structure databases

ProteinModelPortalA0RAS4.
SMRA0RAS4. Positions 1-311.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0RAS4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000066650; EBBACP00000064887; EBBACG00000066641.
GeneID4545661.
GenomeReviewsGene locus BALH_0951 in contig CP000485_GR.
KEGGbtl:BALH_0951.
NMPDRfig|412694.5.peg.969.
PATRIC18994200. VBIBacThu63319_1104.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
GeneTreeEBGT00050000002085.
HOGENOMHBG697135.
OMACSETIFE.
ProtClustDBPRK12435.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0RAS4_BACAH
AccessionPrimary (citable) accession number: A0RAS4
Entry history
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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