A0R951 (FENR1_BACAH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase 1
Short name=FNR 1
Short name=Fd-NADP+ reductase 1
EC=1.18.1.2

Gene names

Ordered Locus Names:

BALH_0343

Organism

Bacillus thuringiensis (strain Al Hakam) [Complete proteome] [HAMAP]

Taxonomic identifier

412694 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity. HAMAP MF_01685
Subunit structure	Homodimer By similarity. HAMAP MF_01685
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 349	349	Ferredoxin--NADP reductase 1 HAMAP MF_01685		PRO_0000364802
Sites
	Binding site	36	1	FAD By similarity
	Binding site	44	1	FAD By similarity
	Binding site	48	1	FAD By similarity
	Binding site	88	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	123	1	FAD; via amide nitrogen By similarity
	Binding site	290	1	FAD By similarity
	Binding site	331	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0R951 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: A6AE7F16F2AD131F	FASTA	349	38,690
	10 20 30 40 50 60 MNREELFDVT VIGGGPAGLY SAFYSGLREM KTKIIEFQPQ LGGKIHVYPE KMIWDIGGLL 70 80 90 100 110 120 PVTGEKLIEQ LVQQGLTFQP EVVLNTKIES IIRNKDGIFT LKTSTGEEHF SKTVIVATGS 130 140 150 160 170 180 GILNPQKLSI EGAERFEVSN LNYTVKSLKR FKNKTVIISG GGNSAIDWAN ELEPIAKKVY 190 200 210 220 230 240 LTYRKEELSG HEAQVKQLMN SSAECFFNTS ITTLIAGDNH EAIEYVELTN HETGEVSQLA 250 260 270 280 290 300 IDEVIINHGY ERDITLLENS ELDVAIIDNY YIAGNANSES SVDGLYAAGD ILKHEGKLHL 310 320 330 340 IAGAFQDAGN AVNKAKQFIQ PDASEYGMVS SHNEVFKKRN RELIKQMMK

References

[1]

"The complete genome sequence of Bacillus thuringiensis Al Hakam." Challacombe J.F., Altherr M.R., Xie G., Bhotika S.S., Brown N., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Green L.D., Han C.S. , Hill K.K., Hitchcock P., Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., Martinez D., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Gilna P., Brettin T.S. J. Bacteriol. 189:3680-3681(2007) [PubMed: 17337577] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Al Hakam.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000485 Genomic DNA. Translation: ABK83744.1.
RefSeq	YP_893251.1. NC_008600.1.
3D structure databases
ProteinModelPortal	A0R951.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000069127; EBBACP00000067364; EBBACG00000069118.
GeneID	4545305.
GenomeReviews	Gene locus BALH_0343 in contig CP000485_GR.
KEGG	btl:BALH_0343.
PATRIC	18992795. VBIBacThu63319_0444.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0492.
GeneTree	EBGT00050000000432.
HOGENOM	HBG669726.
OMA	FNTSITK.
ProtClustDB	CLSK904552.
Enzyme and pathway databases
BioCyc	BTHU412694:BALH_0343-MONOMER.
Family and domain databases
HAMAP	MF_01685. FENR2. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR022890. Fd--NADP_Rdtase_type_2. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
KO	K00384.
PANTHER	PTHR22912:SF53. PTHR22912:SF53. 1 hit.
Pfam	PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProtoNet	Search...

Entry information

Entry name

FENR1_BACAH

Accession

Primary (citable) accession number: A0R951

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program