Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A0R8Z7

- A0R8Z7_BACAH

UniProt

A0R8Z7 - A0R8Z7_BACAH

Protein

Amidophosphoribosyltransferase

Gene

purF

Organism
Bacillus thuringiensis (strain Al Hakam)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (09 Jan 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O.UniRule annotation

    Cofactori

    Binds 1 magnesium ion per subunit.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei18 – 181For GATase activityUniRule annotation

    GO - Molecular functioni

    1. amidophosphoribosyltransferase activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
    2. nucleoside metabolic process Source: InterPro
    3. purine nucleobase biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    GlycosyltransferaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    Purine biosynthesisUniRule annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciBTHU412694:GH1W-339-MONOMER.
    UniPathwayiUPA00074; UER00124.

    Protein family/group databases

    MEROPSiC44.001.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    AmidophosphoribosyltransferaseUniRule annotation (EC:2.4.2.14UniRule annotation)
    Short name:
    ATaseUniRule annotation
    Alternative name(s):
    Glutamine phosphoribosylpyrophosphate amidotransferaseUniRule annotation
    Gene namesi
    Name:purFImported
    Ordered Locus Names:BALH_0289Imported
    OrganismiBacillus thuringiensis (strain Al Hakam)Imported
    Taxonomic identifieri412694 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000000761: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi412694.BALH_0289.

    Structurei

    3D structure databases

    ProteinModelPortaliA0R8Z7.
    SMRiA0R8Z7. Positions 18-466.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0034.
    HOGENOMiHOG000033688.
    KOiK00764.
    OMAiSGIPYEM.
    OrthoDBiEOG6KT2Q1.

    Family and domain databases

    Gene3Di3.40.50.2020. 1 hit.
    3.60.20.10. 1 hit.
    InterProiIPR005854. Amd_phspho_trans.
    IPR017932. GATase_2_dom.
    IPR029055. Ntn_hydrolases_N.
    IPR000836. PRibTrfase_dom.
    IPR029057. PRTase-like.
    [Graphical view]
    PfamiPF00156. Pribosyltran. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000485. Amd_phspho_trans. 1 hit.
    SUPFAMiSSF53271. SSF53271. 1 hit.
    SSF56235. SSF56235. 1 hit.
    TIGRFAMsiTIGR01134. purF. 1 hit.
    PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0R8Z7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERGNPMLAE IKGLNEECGV FGIWGHENAA QVSYYGLHSL QHRGQEGAGI    50
    VVNNGEKIVG HKGLGLISEV FSRGELEGLN GKSAIGHVRY ATAGGSEVAN 100
    VQPLLFRFSD HSMALAHNGN LINAKMLRRE LEAEGSIFQT SSDTEVLLHL 150
    IKRSTKDSLI ESVKEALNKV KGAFAYLLLT GNEMIVALDP NGFRPLSIGK 200
    MGDAYVVASE TCAFDVVGAT YIRDVEPGEL LIINDEGIHV DRFTNEVDHA 250
    ICSMEYIYFA RPDSNIAGIN VHAARKNMGK RLAAEAPIEA DVVTGVPDSS 300
    ISAAIGYAEA TGIPYELGLI KNRYVGRTFI QPSQELREQG VKMKLSAVRG 350
    VVEGKRVVMI DDSIVRGTTS KRIVRMLREA GATEVHVRIA SPPLKYPCFY 400
    GIDIQTRKEL IAANHTVEEI REMIGADSLT FLSEDGLVDA IGRPYEGKYG 450
    GLCMAYFNGD YPTALYDYEQ ELLESMK 477
    Length:477
    Mass (Da):52,089
    Last modified:January 9, 2007 - v1
    Checksum:iE92AA1B798521BB8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000485 Genomic DNA. Translation: ABK83690.1.
    RefSeqiWP_011732424.1. NC_008600.1.
    YP_893197.1. NC_008600.1.

    Genome annotation databases

    EnsemblBacteriaiABK83690; ABK83690; BALH_0289.
    GeneIDi4544203.
    KEGGibtl:BALH_0289.
    PATRICi18992677. VBIBacThu63319_0385.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000485 Genomic DNA. Translation: ABK83690.1 .
    RefSeqi WP_011732424.1. NC_008600.1.
    YP_893197.1. NC_008600.1.

    3D structure databases

    ProteinModelPortali A0R8Z7.
    SMRi A0R8Z7. Positions 18-466.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 412694.BALH_0289.

    Protein family/group databases

    MEROPSi C44.001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK83690 ; ABK83690 ; BALH_0289 .
    GeneIDi 4544203.
    KEGGi btl:BALH_0289.
    PATRICi 18992677. VBIBacThu63319_0385.

    Phylogenomic databases

    eggNOGi COG0034.
    HOGENOMi HOG000033688.
    KOi K00764.
    OMAi SGIPYEM.
    OrthoDBi EOG6KT2Q1.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00124 .
    BioCyci BTHU412694:GH1W-339-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.2020. 1 hit.
    3.60.20.10. 1 hit.
    InterProi IPR005854. Amd_phspho_trans.
    IPR017932. GATase_2_dom.
    IPR029055. Ntn_hydrolases_N.
    IPR000836. PRibTrfase_dom.
    IPR029057. PRTase-like.
    [Graphical view ]
    Pfami PF00156. Pribosyltran. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000485. Amd_phspho_trans. 1 hit.
    SUPFAMi SSF53271. SSF53271. 1 hit.
    SSF56235. SSF56235. 1 hit.
    TIGRFAMsi TIGR01134. purF. 1 hit.
    PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Al HakamImported.

    Entry informationi

    Entry nameiA0R8Z7_BACAH
    AccessioniPrimary (citable) accession number: A0R8Z7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 9, 2007
    Last sequence update: January 9, 2007
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3