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A0R6I8

- A0R6I8_MYCS2

UniProt

A0R6I8 - A0R6I8_MYCS2

Protein
Submitted name:

Transcriptional regulator, TetR family

Gene

MSMEG_6564

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 1 (09 Jan 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotationSAAS annotation

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciMSME246196:GJ4Y-6563-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Transcriptional regulator, TetR familyImported
    Submitted name:
    Transcriptional regulator, TetR family proteinImported
    Gene namesi
    Ordered Locus Names:MSMEG_6564Imported, MSMEI_6387Imported
    OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
    Taxonomic identifieri246196 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000000757: Chromosome, UP000006158: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi246196.MSMEG_6564.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4JKZX-ray1.80A8-189[»]
    4JL3X-ray2.50A/B/C/D9-189[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 HTH tetR-type DNA-binding domain.UniRule annotation
    Contains HTH tetR-type DNA-binding domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG1309.
    HOGENOMiHOG000266637.
    OMAiACMEHED.
    OrthoDBiEOG615VJ0.

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    1.10.357.10. 1 hit.
    InterProiIPR009057. Homeodomain-like.
    IPR001647. HTH_TetR.
    IPR015893. Tet_transcr_reg_TetR-like_C.
    IPR011075. Tet_transcr_reg_TetR-rel_C.
    [Graphical view]
    PfamiPF00440. TetR_N. 1 hit.
    [Graphical view]
    PRINTSiPR00455. HTHTETR.
    SUPFAMiSSF46689. SSF46689. 1 hit.
    SSF48498. SSF48498. 1 hit.
    PROSITEiPS50977. HTH_TETR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0R6I8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTTAEAPRRR SEKSRVAIVE ATRALLLERG FDGLSIEAVA AKAGVGKQTI    50
    YRWWPSRHAL VADVLLEDAD KILARMPKTD DVTADLASWA GTLAAALTTR 100
    RGHAMLKTLM AASLEHEDTA ARLREGFSRP LIESVRDRLR DEDIDADHAQ 150
    AAADALLGAV VNAVLSEGRS YSRQRAETSA RIIVAGLRP 189
    Length:189
    Mass (Da):20,537
    Last modified:January 9, 2007 - v1
    Checksum:i122895106954AF58
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000480 Genomic DNA. Translation: ABK75087.1.
    CP001663 Genomic DNA. Translation: AFP42813.1.
    RefSeqiYP_006571108.1. NC_018289.1.
    YP_890776.1. NC_008596.1.

    Genome annotation databases

    EnsemblBacteriaiABK75087; ABK75087; MSMEG_6564.
    AFP42813; AFP42813; MSMEI_6387.
    GeneIDi4533773.
    KEGGimsg:MSMEI_6387.
    msm:MSMEG_6564.
    PATRICi18085351. VBIMycSme59918_6388.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000480 Genomic DNA. Translation: ABK75087.1 .
    CP001663 Genomic DNA. Translation: AFP42813.1 .
    RefSeqi YP_006571108.1. NC_018289.1.
    YP_890776.1. NC_008596.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4JKZ X-ray 1.80 A 8-189 [» ]
    4JL3 X-ray 2.50 A/B/C/D 9-189 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 246196.MSMEG_6564.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK75087 ; ABK75087 ; MSMEG_6564 .
    AFP42813 ; AFP42813 ; MSMEI_6387 .
    GeneIDi 4533773.
    KEGGi msg:MSMEI_6387.
    msm:MSMEG_6564.
    PATRICi 18085351. VBIMycSme59918_6388.

    Phylogenomic databases

    eggNOGi COG1309.
    HOGENOMi HOG000266637.
    OMAi ACMEHED.
    OrthoDBi EOG615VJ0.

    Enzyme and pathway databases

    BioCyci MSME246196:GJ4Y-6563-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    1.10.357.10. 1 hit.
    InterProi IPR009057. Homeodomain-like.
    IPR001647. HTH_TetR.
    IPR015893. Tet_transcr_reg_TetR-like_C.
    IPR011075. Tet_transcr_reg_TetR-rel_C.
    [Graphical view ]
    Pfami PF00440. TetR_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00455. HTHTETR.
    SUPFAMi SSF46689. SSF46689. 1 hit.
    SSF48498. SSF48498. 1 hit.
    PROSITEi PS50977. HTH_TETR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MC2 155Imported.
    2. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
      Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700084 / mc(2)155 and MC2 155Imported.
    3. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
      Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.
      Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
    4. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
      Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
      Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700084 / mc(2)155 and MC2 155.

    Entry informationi

    Entry nameiA0R6I8_MYCS2
    AccessioniPrimary (citable) accession number: A0R6I8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 9, 2007
    Last sequence update: January 9, 2007
    Last modified: October 1, 2014
    This is version 58 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3