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A0R6I8

- A0R6I8_MYCS2

UniProt

A0R6I8 - A0R6I8_MYCS2

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Protein
Submitted name: Transcriptional regulator, TetR family
Gene
MSMEG_6564, MSMEI_6387
Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotations

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-6563-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Transcriptional regulator, TetR familyImported
Submitted name:
Transcriptional regulator, TetR family proteinImported
Gene namesi
Ordered Locus Names:MSMEG_6564Imported, MSMEI_6387Imported
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000000757: Chromosome, UP000006158: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi246196.MSMEG_6564.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JKZX-ray1.80A8-189[»]
4JL3X-ray2.50A/B/C/D9-189[»]

Family & Domainsi

Sequence similaritiesi

Contains HTH tetR-type DNA-binding domain.SAAS annotations

Phylogenomic databases

eggNOGiCOG1309.
HOGENOMiHOG000266637.
OMAiACMEHED.
OrthoDBiEOG615VJ0.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0R6I8-1 [UniParc]FASTAAdd to Basket

« Hide

MTTAEAPRRR SEKSRVAIVE ATRALLLERG FDGLSIEAVA AKAGVGKQTI    50
YRWWPSRHAL VADVLLEDAD KILARMPKTD DVTADLASWA GTLAAALTTR 100
RGHAMLKTLM AASLEHEDTA ARLREGFSRP LIESVRDRLR DEDIDADHAQ 150
AAADALLGAV VNAVLSEGRS YSRQRAETSA RIIVAGLRP 189
Length:189
Mass (Da):20,537
Last modified:January 9, 2007 - v1
Checksum:i122895106954AF58
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000480 Genomic DNA. Translation: ABK75087.1.
CP001663 Genomic DNA. Translation: AFP42813.1.
RefSeqiYP_006571108.1. NC_018289.1.
YP_890776.1. NC_008596.1.

Genome annotation databases

EnsemblBacteriaiABK75087; ABK75087; MSMEG_6564.
AFP42813; AFP42813; MSMEI_6387.
GeneIDi4533773.
KEGGimsg:MSMEI_6387.
msm:MSMEG_6564.
PATRICi18085351. VBIMycSme59918_6388.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000480 Genomic DNA. Translation: ABK75087.1 .
CP001663 Genomic DNA. Translation: AFP42813.1 .
RefSeqi YP_006571108.1. NC_018289.1.
YP_890776.1. NC_008596.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4JKZ X-ray 1.80 A 8-189 [» ]
4JL3 X-ray 2.50 A/B/C/D 9-189 [» ]
ModBasei Search...

Protein-protein interaction databases

STRINGi 246196.MSMEG_6564.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK75087 ; ABK75087 ; MSMEG_6564 .
AFP42813 ; AFP42813 ; MSMEI_6387 .
GeneIDi 4533773.
KEGGi msg:MSMEI_6387.
msm:MSMEG_6564.
PATRICi 18085351. VBIMycSme59918_6388.

Phylogenomic databases

eggNOGi COG1309.
HOGENOMi HOG000266637.
OMAi ACMEHED.
OrthoDBi EOG615VJ0.

Enzyme and pathway databases

BioCyci MSME246196:GJ4Y-6563-MONOMER.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
1.10.357.10. 1 hit.
InterProi IPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view ]
Pfami PF00440. TetR_N. 1 hit.
[Graphical view ]
PRINTSi PR00455. HTHTETR.
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEi PS50977. HTH_TETR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.
  2. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155 and MC2 155Imported.
  3. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
    Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.M.
    Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155 and MC2 155Imported.
  4. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
    Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
    Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155 and MC2 155.

Entry informationi

Entry nameiA0R6I8_MYCS2
AccessioniPrimary (citable) accession number: A0R6I8
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: July 9, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

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