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Protein
Submitted name:

Transcriptional regulator, TetR family

Gene

MSMEG_6564

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-6563-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Transcriptional regulator, TetR familyImported
Submitted name:
Transcriptional regulator, TetR family proteinImported
Gene namesi
Ordered Locus Names:MSMEG_6564Imported, MSMEI_6387Imported
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000006158 Componenti: Chromosome UP000000757 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi246196.MSMEG_6564.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JKZX-ray1.80A8-189[»]
4JL3X-ray2.50A/B/C/D9-189[»]
ProteinModelPortaliA0R6I8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH tetR-type DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG1309.
HOGENOMiHOG000266637.
OMAiACMEHED.
OrthoDBiEOG615VJ0.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0R6I8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTAEAPRRR SEKSRVAIVE ATRALLLERG FDGLSIEAVA AKAGVGKQTI
60 70 80 90 100
YRWWPSRHAL VADVLLEDAD KILARMPKTD DVTADLASWA GTLAAALTTR
110 120 130 140 150
RGHAMLKTLM AASLEHEDTA ARLREGFSRP LIESVRDRLR DEDIDADHAQ
160 170 180
AAADALLGAV VNAVLSEGRS YSRQRAETSA RIIVAGLRP
Length:189
Mass (Da):20,537
Last modified:January 8, 2007 - v1
Checksum:i122895106954AF58
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK75087.1.
CP001663 Genomic DNA. Translation: AFP42813.1.
RefSeqiYP_006571108.1. NC_018289.1.
YP_890776.1. NC_008596.1.

Genome annotation databases

EnsemblBacteriaiABK75087; ABK75087; MSMEG_6564.
AFP42813; AFP42813; MSMEI_6387.
GeneIDi4533773.
KEGGimsm:MSMEG_6564.
PATRICi18085351. VBIMycSme59918_6388.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK75087.1.
CP001663 Genomic DNA. Translation: AFP42813.1.
RefSeqiYP_006571108.1. NC_018289.1.
YP_890776.1. NC_008596.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JKZX-ray1.80A8-189[»]
4JL3X-ray2.50A/B/C/D9-189[»]
ProteinModelPortaliA0R6I8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246196.MSMEG_6564.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK75087; ABK75087; MSMEG_6564.
AFP42813; AFP42813; MSMEI_6387.
GeneIDi4533773.
KEGGimsm:MSMEG_6564.
PATRICi18085351. VBIMycSme59918_6388.

Phylogenomic databases

eggNOGiCOG1309.
HOGENOMiHOG000266637.
OMAiACMEHED.
OrthoDBiEOG615VJ0.

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-6563-MONOMER.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.
  2. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
    Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  3. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
    Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.
    Genome Biol. 8:R20.1-R20.9(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  4. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
    Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
    Genome Res. 19:128-135(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155 and MC2 155.

Entry informationi

Entry nameiA0R6I8_MYCS2
AccessioniPrimary (citable) accession number: A0R6I8
Entry historyi
Integrated into UniProtKB/TrEMBL: January 8, 2007
Last sequence update: January 8, 2007
Last modified: March 31, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.