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A0R6I8

- A0R6I8_MYCS2

UniProt

A0R6I8 - A0R6I8_MYCS2

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Protein
Submitted name:

Transcriptional regulator, TetR family

Gene

MSMEG_6564

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotation

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-6563-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Transcriptional regulator, TetR familyImported
Submitted name:
Transcriptional regulator, TetR family proteinImported
Gene namesi
Ordered Locus Names:MSMEG_6564Imported, MSMEI_6387Imported
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000000757: Chromosome, UP000006158: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi246196.MSMEG_6564.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JKZX-ray1.80A8-189[»]
4JL3X-ray2.50A/B/C/D9-189[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH tetR-type DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG1309.
HOGENOMiHOG000266637.
OMAiACMEHED.
OrthoDBiEOG615VJ0.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0R6I8 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTTAEAPRRR SEKSRVAIVE ATRALLLERG FDGLSIEAVA AKAGVGKQTI
60 70 80 90 100
YRWWPSRHAL VADVLLEDAD KILARMPKTD DVTADLASWA GTLAAALTTR
110 120 130 140 150
RGHAMLKTLM AASLEHEDTA ARLREGFSRP LIESVRDRLR DEDIDADHAQ
160 170 180
AAADALLGAV VNAVLSEGRS YSRQRAETSA RIIVAGLRP
Length:189
Mass (Da):20,537
Last modified:January 9, 2007 - v1
Checksum:i122895106954AF58
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000480 Genomic DNA. Translation: ABK75087.1.
CP001663 Genomic DNA. Translation: AFP42813.1.
RefSeqiYP_006571108.1. NC_018289.1.
YP_890776.1. NC_008596.1.

Genome annotation databases

EnsemblBacteriaiABK75087; ABK75087; MSMEG_6564.
AFP42813; AFP42813; MSMEI_6387.
GeneIDi4533773.
KEGGimsg:MSMEI_6387.
msm:MSMEG_6564.
PATRICi18085351. VBIMycSme59918_6388.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000480 Genomic DNA. Translation: ABK75087.1 .
CP001663 Genomic DNA. Translation: AFP42813.1 .
RefSeqi YP_006571108.1. NC_018289.1.
YP_890776.1. NC_008596.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4JKZ X-ray 1.80 A 8-189 [» ]
4JL3 X-ray 2.50 A/B/C/D 9-189 [» ]
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 246196.MSMEG_6564.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK75087 ; ABK75087 ; MSMEG_6564 .
AFP42813 ; AFP42813 ; MSMEI_6387 .
GeneIDi 4533773.
KEGGi msg:MSMEI_6387.
msm:MSMEG_6564.
PATRICi 18085351. VBIMycSme59918_6388.

Phylogenomic databases

eggNOGi COG1309.
HOGENOMi HOG000266637.
OMAi ACMEHED.
OrthoDBi EOG615VJ0.

Enzyme and pathway databases

BioCyci MSME246196:GJ4Y-6563-MONOMER.

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
1.10.357.10. 1 hit.
InterProi IPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view ]
Pfami PF00440. TetR_N. 1 hit.
[Graphical view ]
PRINTSi PR00455. HTHTETR.
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEi PS50977. HTH_TETR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.
  2. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  3. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
    Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.
    Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  4. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
    Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
    Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155 and MC2 155.

Entry informationi

Entry nameiA0R6I8_MYCS2
AccessioniPrimary (citable) accession number: A0R6I8
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3