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A0R607 (A0R607_MYCS2) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Ordered Locus Names:MSMEG_6382 EMBL ABK72795.1
OrganismMycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [Reference proteome] [HAMAP] EMBL ABK72795.1
Taxonomic identifier246196 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length468 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains FAD-binding PCMH-type domain. SAAS SAAS006094

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding60 – 667FAD PDB 4AUT PDB 4F4Q
Nucleotide binding129 – 1324FAD PDB 4AUT PDB 4F4Q
Nucleotide binding136 – 1394FAD PDB 4AUT PDB 4F4Q

Sites

Binding site241FAD PDB 4AUT PDB 4F4Q
Binding site701FAD; via carbonyl oxygen PDB 4AUT PDB 4F4Q
Binding site1241FAD; via amide nitrogen PDB 4AUT PDB 4F4Q
Binding site1851FAD; via carbonyl oxygen PDB 4AUT PDB 4F4Q
Binding site1911FAD; via amide nitrogen and carbonyl oxygen PDB 4AUT PDB 4F4Q
Binding site4221FAD PDB 4AUT PDB 4F4Q

Sequences

Sequence LengthMass (Da)Tools
A0R607 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: CF00458CEE7E6549

FASTA46851,134
        10         20         30         40         50         60 
MGAVPSLTMS TTEFPTTTKR LMGWGRTAPT VASVLSTSDP EVIVRAVTRA AEEGGRGVIA 

        70         80         90        100        110        120 
RGLGRSYGDN AQNGGGLVID MPALNRIHSI DSGTRLVDVD AGVSLDQLMK AALPHGLWVP 

       130        140        150        160        170        180 
VLPGTRQVTV GGAIGCDIHG KNHHSAGSFG NHVRSMELLT ANGEVRHLTP AGPDSDLFWA 

       190        200        210        220        230        240 
TVGGNGLTGI ILRATIEMTP TETAYFIADG DVTGSLDETI AFHSDGSEAN YTYSSAWFDA 

       250        260        270        280        290        300 
ISKPPKLGRA AISRGSLAKL DQLPSKLQKD PLKFDAPQLL TLPDIFPNGL ANKFTFMPIG 

       310        320        330        340        350        360 
ELWYRKSGTY RNKVQNLTQF YHPLDMFGEW NRAYGSAGFL QYQFVVPTEA VEEFKSIIVD 

       370        380        390        400        410        420 
IQRSGHYSFL NVFKLFGPGN QAPLSFPIPG WNVCVDFPIK AGLHEFVTEL DRRVLEFGGR 

       430        440        450        460 
LYTAKDSRTT AETFHAMYPR IDEWIRIRRS VDPDGVFASD MARRLQLL 

« Hide

References

« Hide 'large scale' references
[1]Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700084 / mc(2)155.
[2]"Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis."
Neres J., Pojer F., Molteni E., Chiarelli L.R., Dhar N., Boy-Rottger S., Buroni S., Fullam E., Degiacomi G., Lucarelli A.P., Read R.J., Zanoni G., Edmondson D.E., De Rossi E., Pasca M.R., McKinney J.D., Dyson P.J., Riccardi G. expand/collapse author list , Mattevi A., Cole S.T., Binda C.
Sci. Transl. Med. 4:150ra121-150ra121(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH FAD.
[3]"Crystal structure of decaprenylphosphoryl-?- D-ribose 2'-epimerase from Mycobacterium smegmatis."
Li H., Jogl G.
Proteins 81:538-543(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 66-468.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000480 Genomic DNA. Translation: ABK72795.1.
RefSeqYP_890595.1. NC_008596.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4AUTX-ray2.10A1-468[»]
4F4QX-ray2.62A1-468[»]
4G3TX-ray2.35A66-468[»]
4G3UX-ray2.69A/B66-468[»]
ProteinModelPortalA0R607.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING246196.MSMEG_6382.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK72795; ABK72795; MSMEG_6382.
GeneID4532115.
KEGGmsm:MSMEG_6382.
PATRIC18084993. VBIMycSme59918_6209.

Phylogenomic databases

eggNOGCOG0277.
HOGENOMHOG000010204.
KOK16653.
OMAETIAFHS.
OrthoDBEOG69WFG8.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-17534.
MSME246196:GJ4Y-6381-MONOMER.

Family and domain databases

Gene3D3.30.465.10. 1 hit.
InterProIPR007173. ALO.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR006094. Oxid_FAD_bind_N.
[Graphical view]
PfamPF04030. ALO. 1 hit.
PF01565. FAD_binding_4. 1 hit.
[Graphical view]
SUPFAMSSF56176. SSF56176. 1 hit.
PROSITEPS51387. FAD_PCMH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0R607_MYCS2
AccessionPrimary (citable) accession number: A0R607
Entry history
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: June 11, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)