A0R607 (A0R607_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Oxidoreductase, FAD-binding EMBL ABK72795.1

Gene names

Ordered Locus Names:

MSMEG_6382 EMBL ABK72795.1

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [Reference proteome] [HAMAP] EMBL ABK72795.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium smegmatis

Protein attributes

Sequence length	468 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 FAD-binding PCMH-type domain. SAAS SAAS006094

Ontologies

Keywords
Technical term	3D-structure PDB 4AUT PDB 4F4Q PDB 4G3T PDB 4G3U Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	D-arabinono-1,4-lactone oxidase activity Inferred from electronic annotation. Source: InterPro UDP-N-acetylmuramate dehydrogenase activity Inferred from electronic annotation. Source: InterPro flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0R607 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: CF00458CEE7E6549	FASTA	468	51,134
	10 20 30 40 50 60 MGAVPSLTMS TTEFPTTTKR LMGWGRTAPT VASVLSTSDP EVIVRAVTRA AEEGGRGVIA 70 80 90 100 110 120 RGLGRSYGDN AQNGGGLVID MPALNRIHSI DSGTRLVDVD AGVSLDQLMK AALPHGLWVP 130 140 150 160 170 180 VLPGTRQVTV GGAIGCDIHG KNHHSAGSFG NHVRSMELLT ANGEVRHLTP AGPDSDLFWA 190 200 210 220 230 240 TVGGNGLTGI ILRATIEMTP TETAYFIADG DVTGSLDETI AFHSDGSEAN YTYSSAWFDA 250 260 270 280 290 300 ISKPPKLGRA AISRGSLAKL DQLPSKLQKD PLKFDAPQLL TLPDIFPNGL ANKFTFMPIG 310 320 330 340 350 360 ELWYRKSGTY RNKVQNLTQF YHPLDMFGEW NRAYGSAGFL QYQFVVPTEA VEEFKSIIVD 370 380 390 400 410 420 IQRSGHYSFL NVFKLFGPGN QAPLSFPIPG WNVCVDFPIK AGLHEFVTEL DRRVLEFGGR 430 440 450 460 LYTAKDSRTT AETFHAMYPR IDEWIRIRRS VDPDGVFASD MARRLQLL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.
[2]	"Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis." Neres J., Pojer F., Molteni E., Chiarelli L.R., Dhar N., Boy-Rottger S., Buroni S., Fullam E., Degiacomi G., Lucarelli A.P., Read R.J., Zanoni G., Edmondson D.E., De Rossi E., Pasca M.R., McKinney J.D., Dyson P.J., Riccardi G. , Mattevi A., Cole S.T., Binda C. Sci. Transl. Med. 4:150ra121-150ra121(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).
[3]	"Structural Studies of the Tuberculosis Drug Target Decaprenylphosphoryl-beta-D-Ribose 2'-Epimerase from Mycobacterium smegmatis." Li H., Jogl G. Submitted (JUL-2012) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 66-468.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000480 Genomic DNA. Translation: ABK72795.1.

RefSeq

YP_890595.1. NC_008596.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4AUT	X-ray	2.10	A	1-468	[»]
4F4Q	X-ray	2.62	A	1-468	[»]
4G3T	X-ray	2.35	A	66-468	[»]
4G3U	X-ray	2.69	A/B	66-468	[»]

ProteinModelPortal

A0R607.

ModBase

Search...

Protein-protein interaction databases

STRING

246196.MSMEG_6382.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

ABK72795; ABK72795; MSMEG_6382.

GeneID

4532115.

KEGG

msm:MSMEG_6382.

PATRIC

18084993. VBIMycSme59918_6209.

Phylogenomic databases

eggNOG

COG0277.

HOGENOM

HOG000010204.

KO

K16653.

OMA

TLALDFP.

ProtClustDB

CLSK872248.

Enzyme and pathway databases

BioCyc

MetaCyc:MONOMER-17534.
MSME246196:GJ4Y-6381-MONOMER.

Family and domain databases

Gene3D

3.30.465.10. 1 hit.

InterPro

IPR007173. ALO.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR006094. Oxid_FAD_bind_N.
[Graphical view]

Pfam

PF04030. ALO. 1 hit.
PF01565. FAD_binding_4. 1 hit.
[Graphical view]

SUPFAM

SSF56176. FAD-binding_2. 1 hit.

PROSITE

PS51387. FAD_PCMH. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

A0R607_MYCS2

Accession

Primary (citable) accession number: A0R607

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	May 1, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)