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Protein

Putative phenylalanine aminotransferase

Gene

pat

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May catalyze the transamination reaction in phenylalanine biosynthesis.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase
LigandPyridoxal phosphate

Enzyme and pathway databases

BioCyciMSME246196:G1H7P-6318-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phenylalanine aminotransferaseUniRule annotation (EC:2.6.1.-UniRule annotation)
Gene namesi
Name:patUniRule annotation
Ordered Locus Names:MSMEG_6351, MSMEI_6185
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium fortuitum complex
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000244961 – 361Putative phenylalanine aminotransferaseAdd BLAST361

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei215N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi246196.MSMEG_6351

Structurei

3D structure databases

ProteinModelPortaliA0R5X8
SMRiA0R5X8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CIH Bacteria
COG0079 LUCA
HOGENOMiHOG000288510
KOiK00817
OMAiHGFLVYR
OrthoDBiPOG091H05S1

Family and domain databases

Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
HAMAPiMF_01023 HisC_aminotrans_2, 1 hit
MF_01513 Phe_aminotrans_2, 1 hit
InterProiView protein in InterPro
IPR001917 Aminotrans_II_pyridoxalP_BS
IPR004839 Aminotransferase_I/II
IPR005861 HisP_aminotrans
IPR024892 Pat
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00155 Aminotran_1_2, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01141 hisC, 1 hit
PROSITEiView protein in PROSITE
PS00599 AA_TRANSFER_CLASS_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0R5X8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSIRLRAEMA DLPAYAPGKT VPGAIKIASN ETVHGPLPSV REAILKATDL
60 70 80 90 100
INRYPDNGYL DLRERLAKHV NFAPENISVG CGSVSLCQQL IQITSSVGDE
110 120 130 140 150
VLFAWRSFEI YPLQVRTAGA TPVAVALRDH THDLDAMLAA ITDRTRLIFV
160 170 180 190 200
CNPNNPTSTV VDPGELARFV AAVPPHILVV LDEAYVEYIR DGLLPDSLGL
210 220 230 240 250
VREHRNVVVL RTFSKAYGLA GLRVGYAVAD PEIVTALGKV YVPFSATSVS
260 270 280 290 300
QAAAIACLDA ADELLARTDA VVAERTRVSD ALRAAGYTLP PSQANFVWLP
310 320 330 340 350
LAERTLDFVA RAADNRIIVR PYGEDGVRVT IGAPHENDAF LDFAQRWIAP
360
GGAGPRTGDS A
Length:361
Mass (Da):38,871
Last modified:January 9, 2007 - v1
Checksum:i1E1851D681D311E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA Translation: ABK70318.1
CP001663 Genomic DNA Translation: AFP42612.1
RefSeqiWP_011731224.1, NZ_CP009494.1
YP_890566.1, NC_008596.1

Genome annotation databases

EnsemblBacteriaiABK70318; ABK70318; MSMEG_6351
AFP42612; AFP42612; MSMEI_6185
GeneIDi4535223
KEGGimsb:LJ00_31400
msg:MSMEI_6185
msm:MSMEG_6351
PATRICifig|246196.19.peg.6182

Entry informationi

Entry nameiPATR_MYCS2
AccessioniPrimary (citable) accession number: A0R5X8
Secondary accession number(s): I7GAM4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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