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Protein

HTH-type transcriptional repressor KstR

Gene

kstR

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Controls the expression of genes used for utilizing diverse lipids as energy sources.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi41 – 60H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • regulation of transcription, DNA-templated Source: UniProtKB
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional repressor KstR
Gene namesi
Name:kstR
Ordered Locus Names:MSMEG_6042, MSMEI_5881
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium fortuitum complex
Proteomesi
  • UP000006158 Componenti: Chromosome
  • UP000000757 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004050291 – 204HTH-type transcriptional repressor KstRAdd BLAST204

Interactioni

Subunit structurei

Homodimer.Curated

Protein-protein interaction databases

STRINGi246196.MSMEG_6042

Structurei

3D structure databases

ProteinModelPortaliA0R528
SMRiA0R528
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 78HTH tetR-typePROSITE-ProRule annotationAdd BLAST61

Phylogenomic databases

eggNOGiENOG4108SGK Bacteria
ENOG4111HR8 LUCA
HOGENOMiHOG000052226
KOiK22107
OMAiMTRAFMF
OrthoDBiPOG091H02BD

Family and domain databases

InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR001647 HTH_TetR
PfamiView protein in Pfam
PF00440 TetR_N, 1 hit
PRINTSiPR00455 HTHTETR
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS50977 HTH_TETR_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0R528-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNVAVLSES ELGSEAQRER RKRILDATLA IASKGGYEAV QMRAVAERAD
60 70 80 90 100
VAVGTLYRYF PSKVHLLVSA LGREFERIDA KTDRAALAGG TPYQRLNFMV
110 120 130 140 150
GKLNRAMQRN PLLTEAMTRA FVFADASAAG EVDHVGKLMD SMFARAMSDG
160 170 180 190 200
EPTEDQYHIA RVISDVWLSN LLAWLTRRAS ATDVSKRLDL AVRLLIGTEE

QPKI
Length:204
Mass (Da):22,571
Last modified:January 9, 2007 - v1
Checksum:i1125BEBE034F88C2
GO

Sequence cautioni

The sequence AFP42314 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA Translation: ABK75291.1
CP001663 Genomic DNA Translation: AFP42314.1 Different initiation.
RefSeqiWP_011730995.1, NZ_CP009494.1
YP_890266.1, NC_008596.1

Genome annotation databases

EnsemblBacteriaiABK75291; ABK75291; MSMEG_6042
AFP42314; AFP42314; MSMEI_5881
GeneIDi4531834
KEGGimsg:MSMEI_5881
msm:MSMEG_6042
PATRICifig|246196.19.peg.5878

Similar proteinsi

Entry informationi

Entry nameiKSTR_MYCS2
AccessioniPrimary (citable) accession number: A0R528
Secondary accession number(s): I7GG00
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 8, 2011
Last sequence update: January 9, 2007
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health