Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A0R4Q6 (A0R4Q6_MYCS2) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Ordered Locus Names:MSMEG_5918 EMBL ABK74975.1
OrganismMycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [Reference proteome] [HAMAP] EMBL ABK74975.1
Taxonomic identifier246196 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the cytochrome P450 family. RuleBase RU000461

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region4 – 74Sulfate 1 binding

Sites

Metal binding3431Iron (heme axial ligand) PDB 2YOO PDB 3ZBY
Binding site2391Sulfate 2
Binding site3781Sulfate 2

Sequences

Sequence LengthMass (Da)Tools
A0R4Q6 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: 9195ECA2F9D8D509

FASTA40144,901
        10         20         30         40         50         60 
MTQMLTRPDV DLVNGMFYAD GGAREAYRWM RANEPVFRDR NGLAAATTYQ AVLDAERNPE 

        70         80         90        100        110        120 
LFSSTGGIRP DQPGMPYMID MDDPQHLLRR KLVNAGFTRK RVMDKVDSIG RLCDTLIDAV 

       130        140        150        160        170        180 
CERGECDFVR DIAAPLPMAV IGDMLGVLPT ERDMLLKWSD DLVCGLSSHV DEAAIQKLMD 

       190        200        210        220        230        240 
TFAAYTEFTK DVITKRRAEP TDDLFSVLVN SEVEGQRMSD DEIVFETLLI LIGGDETTRH 

       250        260        270        280        290        300 
TLSGGTEQLL RHRDQWDALV ADVDLLPGAI EEMLRWTSPV KNMCRTLTAD TVFHGTELRA 

       310        320        330        340        350        360 
GEKIMLMFES ANFDESVFGD PDNFRIDRNP NSHVAFGFGT HFCLGNQLAR LELRLMTERV 

       370        380        390        400 
LRRLPDLRLA DDAPVPLRPA NFVSGPESMP VVFTPSAPVL A 

« Hide

References

« Hide 'large scale' references
[1]Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700084 / mc(2)155.
[2]"A highly conserved mycobacterial cholesterol catabolic pathway."
Garcia-Fernandez E., Frank D.J., Galan B., Kells P.M., Podust L.M., Garcia J.L., Ortiz de Montellano P.R.
Environ. Microbiol. 15:2342-2359(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.69 ANGSTROMS) OF 4-401 IN COMPLEX WITH HEME AND SULFATE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000480 Genomic DNA. Translation: ABK74975.1.
RefSeqYP_890144.1. NC_008596.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2YOOX-ray1.69A/B/C/D4-401[»]
3ZBYX-ray1.93A/B/C/D/E/F1-401[»]
ProteinModelPortalA0R4Q6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING246196.MSMEG_5918.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK74975; ABK74975; MSMEG_5918.
GeneID4533135.
KEGGmsm:MSMEG_5918.
PATRIC18084077. VBIMycSme59918_5758.

Phylogenomic databases

eggNOGCOG2124.
HOGENOMHOG000243680.
KOK16046.
OMARRRPANF.
OrthoDBEOG6JB11P.

Enzyme and pathway databases

BioCycMSME246196:GJ4Y-5917-MONOMER.

Family and domain databases

Gene3D1.10.630.10. 1 hit.
InterProIPR001128. Cyt_P450.
IPR002397. Cyt_P450_B.
IPR017972. Cyt_P450_CS.
[Graphical view]
PfamPF00067. p450. 1 hit.
[Graphical view]
PRINTSPR00359. BP450.
PR00385. P450.
SUPFAMSSF48264. SSF48264. 1 hit.
PROSITEPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0R4Q6_MYCS2
AccessionPrimary (citable) accession number: A0R4Q6
Entry history
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)