A0R4Q6 (A0R4Q6_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
P450 heme-thiolate protein EMBL ABK74975.1

Gene names

Ordered Locus Names:

MSMEG_5918 EMBL ABK74975.1

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [Reference proteome] [HAMAP] EMBL ABK74975.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium smegmatis

Protein attributes

Sequence length	401 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the cytochrome P450 family. RuleBase RU000461

Ontologies

Keywords
Ligand	Heme RuleBase RU000461 Iron Metal-binding
Molecular function	Monooxygenase RuleBase RU000461 Oxidoreductase
Technical term	3D-structure PDB 2YOO PDB 3ZBY Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro monooxygenase activity Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0R4Q6 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 9195ECA2F9D8D509	FASTA	401	44,901
	10 20 30 40 50 60 MTQMLTRPDV DLVNGMFYAD GGAREAYRWM RANEPVFRDR NGLAAATTYQ AVLDAERNPE 70 80 90 100 110 120 LFSSTGGIRP DQPGMPYMID MDDPQHLLRR KLVNAGFTRK RVMDKVDSIG RLCDTLIDAV 130 140 150 160 170 180 CERGECDFVR DIAAPLPMAV IGDMLGVLPT ERDMLLKWSD DLVCGLSSHV DEAAIQKLMD 190 200 210 220 230 240 TFAAYTEFTK DVITKRRAEP TDDLFSVLVN SEVEGQRMSD DEIVFETLLI LIGGDETTRH 250 260 270 280 290 300 TLSGGTEQLL RHRDQWDALV ADVDLLPGAI EEMLRWTSPV KNMCRTLTAD TVFHGTELRA 310 320 330 340 350 360 GEKIMLMFES ANFDESVFGD PDNFRIDRNP NSHVAFGFGT HFCLGNQLAR LELRLMTERV 370 380 390 400 LRRLPDLRLA DDAPVPLRPA NFVSGPESMP VVFTPSAPVL A

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000480 Genomic DNA. Translation: ABK74975.1.

RefSeq

YP_890144.1. NC_008596.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2YOO	X-ray	1.69	A/B/C/D	1-401	[»]
3ZBY	X-ray	1.93	A/B/C/D/E/F	1-401	[»]

ProteinModelPortal

A0R4Q6.

ModBase

Search...

Protein-protein interaction databases

STRING

246196.MSMEG_5918.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

ABK74975; ABK74975; MSMEG_5918.

GeneID

4533135.

KEGG

msm:MSMEG_5918.

PATRIC

18084077. VBIMycSme59918_5758.

Phylogenomic databases

eggNOG

COG2124.

HOGENOM

HOG000243680.

KO

K16046.

OMA

DEQTIQK.

ProtClustDB

CLSK792538.

Enzyme and pathway databases

BioCyc

MSME246196:GJ4Y-5917-MONOMER.

Family and domain databases

Gene3D

1.10.630.10. 1 hit.

InterPro

IPR001128. Cyt_P450.
IPR002397. Cyt_P450_B.
IPR017972. Cyt_P450_CS.
[Graphical view]

Pfam

PF00067. p450. 1 hit.
[Graphical view]

PRINTS

PR00359. BP450.
PR00385. P450.

SUPFAM

SSF48264. Cytochrome_P450. 1 hit.

PROSITE

PS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

A0R4Q6_MYCS2

Accession

Primary (citable) accession number: A0R4Q6

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)