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A0R3N9 (G6PI_MYCS2) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:MSMEG_5541, MSMEI_5387
OrganismMycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [Reference proteome] [HAMAP]
Taxonomic identifier246196 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_1000013989

Sites

Active site3531Proton donor By similarity
Active site3841 By similarity
Active site5101 By similarity

Sequences

Sequence LengthMass (Da)Tools
A0R3N9 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: E48F1BD4A53DCD73

FASTA54959,630
        10         20         30         40         50         60 
MSADITETPA WQALSDHHAE IGDRHLTELF ADDPARGTEL ALTVGDLYID YSKHRVTRRT 

        70         80         90        100        110        120 
LDLLVDLARA AGLEERRDAM FAGEHINTSE DRAVLHTALR LPRDAKLVVD GQDVVADVHD 

       130        140        150        160        170        180 
VLDRMGDFTD RLRSGEWTGA TGERITTVVN IGIGGSDLGP VMVYDALRHY ADAGISARFV 

       190        200        210        220        230        240 
SNVDPADLVA KLDGLEPAKT LFIVASKTFS TLETLTNATA ARRWLTDALG DAAVAKHFVA 

       250        260        270        280        290        300 
VSTNKKLVDE FGINTDNMFG FWDWVGGRYS VDSAIGLSVM AVIGKERFAE FLAGFHIVDE 

       310        320        330        340        350        360 
HFRTAPLHQN APALLGLIGL WYSNFFGAQS RAVLPYSNDL SRFAAYLQQL TMESNGKSVR 

       370        380        390        400        410        420 
ADGTPVSTDT GEIFWGEPGT NGQHAFYQLL HQGTRLVPAD FIGFSQPTDD LPTADGTGSM 

       430        440        450        460        470        480 
HDLLMSNFFA QTQVLAFGKT ADAIASEGTP ADVVPHKVMP GNRPTTSILA TKLTPSVVGQ 

       490        500        510        520        530        540 
LIALYEHQVF TEGVIWGIDS FDQWGVELGK TQAKALLPVL TGDKSPAAQS DTSTDALVRR 


YRTERGRPA 

« Hide

References

[1]Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700084 / mc(2)155.
[2]"Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.
Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700084 / mc(2)155.
[3]"Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000480 Genomic DNA. Translation: ABK73757.1.
CP001663 Genomic DNA. Translation: AFP41828.1.
RefSeqYP_006570123.1. NC_018289.1.
YP_889777.1. NC_008596.1.

3D structure databases

ProteinModelPortalA0R3N9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING246196.MSMEG_5541.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK73757; ABK73757; MSMEG_5541.
AFP41828; AFP41828; MSMEI_5387.
GeneID13426222.
4534436.
KEGGmsg:MSMEI_5387.
msm:MSMEG_5541.
PATRIC18083347. VBIMycSme59918_5399.

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMALKMHFVS.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycMSME246196:GJ4Y-5539-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_MYCS2
AccessionPrimary (citable) accession number: A0R3N9
Secondary accession number(s): I7FSK4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: February 19, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways