A0R3E7 (A0R3E7_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase I HAMAP MF_01877
EC=2.1.1.198 HAMAP MF_01877

Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase HAMAP MF_01877
rRNA (cytidine-2'-O-)-methyltransferase RsmI HAMAP MF_01877

Gene names

Name:	rsmI HAMAP MF_01877
Ordered Locus Names:	MSMEG_5445

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK69684.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	278 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP MF_01877
Catalytic activity	S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA. HAMAP MF_01877
Subcellular location	Cytoplasm By similarity HAMAP MF_01877.
Sequence similarities	Belongs to the methyltransferase superfamily. RsmI family. HAMAP MF_01877

Ontologies

Keywords
Biological process	rRNA processing HAMAP MF_01877
Cellular component	Cytoplasm HAMAP MF_01877
Ligand	S-adenosyl-L-methionine HAMAP MF_01877
Molecular function	Methyltransferase HAMAP MF_01877 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	enzyme-directed rRNA 2'-O-methylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (cytosine-2'-O-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0R3E7 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 44BAEEF7AEA45466	FASTA	278	29,525
	10 20 30 40 50 60 MTLGKLLIGA TPLGQPSDAS ARLVRALRDA DIVAAEDTRR IRSLAQALEV TPTGRVLSFF 70 80 90 100 110 120 DQNEASRVPG LVEEIRAGAT VLVVSDAGMP LINDPGYRLV AACAEAGLPV SCLPGPSAVT 130 140 150 160 170 180 TALAVSGLAS DRFCFEGFAP RKHAARMTWL QTLAHEMRTC VFFESPRRLA ETLRDAVDAL 190 200 210 220 230 240 GADRRAVVCR ELTKTHEEIK RGSLAELADW ADDGVLGEIT VVLAGATPTA DLPTLVAEVE 250 260 270 ELVAAGTRVK DACARVVADN PGAPSKRELY DAVLRSRD

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000480 Genomic DNA. Translation: ABK69684.1.
RefSeq	YP_889685.1. NC_008596.1.
3D structure databases
ProteinModelPortal	A0R3E7.
ModBase	Search...
Protein-protein interaction databases
STRING	A0R3E7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000041501; EBMYCP00000039838; EBMYCG00000041496.
GeneID	4537388.
GenomeReviews	Gene locus MSMEG_5445 in contig CP000480_GR.
KEGG	msm:MSMEG_5445.
NMPDR	fig|246196.1.peg.5426.
PATRIC	18083161. VBIMycSme59918_5307.
TIGR	MSMEG_5445.
Phylogenomic databases
eggNOG	COG0313.
GeneTree	EBGT00050000017256.
HOGENOM	HBG529058.
OMA	IASDRFC.
PhylomeDB	A0R3E7.
ProtClustDB	CLSK725743.
Family and domain databases
HAMAP	MF_01877. 16SrRNA_methyltr_I. [Tree]
InterPro	IPR000878. 4pyrrol_Mease. IPR014777. 4pyrrole_Mease_sub1. IPR014776. 4pyrrole_Mease_sub2. IPR008189. rRNA_ssu_MeTfrase_I. IPR018063. SAM_MeTrfase_RsmI_CS. [Graphical view]
Gene3D	G3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit. G3DSA:3.30.950.10. 4pyrrole_Mease_sub2. 1 hit.
KO	K07056.
PANTHER	PTHR21091:SF18. PTHR21091:SF18. 1 hit.
Pfam	PF00590. TP_methylase. 1 hit. [Graphical view]
PIRSF	PIRSF005917. MTase_YraL. 1 hit.
SUPFAM	SSF53790. Cor/por_Metransf. 1 hit.
TIGRFAMs	TIGR00096. TIGR00096. 1 hit.
PROSITE	PS01296. RSMI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0R3E7_MYCS2

Accession

Primary (citable) accession number: A0R3E7

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)