A0R2H8 (A0R2H8_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
1-pyrroline-5-carboxylate dehydrogenase EMBL ABK71820.1
EC=1.5.1.12 EMBL ABK71820.1

Gene names

Name:	pruA EMBL ABK71820.1
Ordered Locus Names:	MSMEG_5119

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK71820.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	542 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ABK71820.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proline biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: InterPro
Molecular function	1-pyrroline-5-carboxylate dehydrogenase activity Inferred from electronic annotation. Source: EC oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0R2H8 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: E6A7169FCAE35625	FASTA	542	58,434
	10 20 30 40 50 60 MDAITDVPTP ANEPIHDYAP GSQERTRLTT ALHDLASTHI DLPHVIGGEH RMGSGARIDV 70 80 90 100 110 120 VQPHRHSAKL GTLTNAEHAD ASAAIEAAIA AKQDWAALPF DQRAAVFLRA ADLLSGPWRE 130 140 150 160 170 180 KVAAATMLGQ SKSAYQAEID APCELIDFWR FNVAFARQIL AQQPISSPGV WNRTDHRPLE 190 200 210 220 230 240 GFVYAITPFN FTAIAGNLPT APALMGNTVV WKPSPTQTFA AYLTMQLLEA AGLPPGVINL 250 260 270 280 290 300 VTGDGIAVSE VALKDPRLAG IHFTGSTATF QHLWREVGAN IDRYHTYPRL VGETGGKDFV 310 320 330 340 350 360 LAHSSAHPDV LRTALIRGAF DYQGQKCSAA SRAFIPRSVW QKMGDDFLSA TEALRYGDVA 370 380 390 400 410 420 DLTNYGGAVI DDRAFAKNVK AIERAKSAPG VTIAAGGEYD DSEGYFVRPT VLLSDDPTDD 430 440 450 460 470 480 AFCTEYFGPI LAVHVYPDDE YERIIDVVDT GAKYGLTGAV IADDRTAVQQ ALDGLRYAAG 490 500 510 520 530 540 NFYINDKPTG AVVGQQPFGG SRASGTNDKA GSAQNLMRWT SARSIKETFV PPTNHTYPHM EA

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000480 Genomic DNA. Translation: ABK71820.1.
RefSeq	YP_889366.1. NC_008596.1.
3D structure databases
ProteinModelPortal	A0R2H8.
ModBase	Search...
Protein-protein interaction databases
STRING	A0R2H8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000046226; EBMYCP00000044563; EBMYCG00000046221.
GeneID	4534098.
GenomeReviews	Gene locus MSMEG_5119 in contig CP000480_GR.
KEGG	msm:MSMEG_5119.
NMPDR	fig|246196.1.peg.5104.
PATRIC	18082529. VBIMycSme59918_4993.
TIGR	MSMEG_5119.
Phylogenomic databases
eggNOG	COG1012.
GeneTree	EBGT00050000015660.
HOGENOM	HBG752218.
OMA	CELVDFW.
PhylomeDB	A0R2H8.
ProtClustDB	CLSK871904.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR005931. Delta1-pyrroline-5-COlate_DH-1. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00294.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01236. D1pyr5carbox1. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0R2H8_MYCS2

Accession

Primary (citable) accession number: A0R2H8

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)