A0R242 (A0R242_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2 HAMAP MF_00064
EC=2.7.7.4 HAMAP MF_00064

Alternative name(s):
ATP-sulfurylase small subunit HAMAP MF_00064
Sulfate adenylate transferase HAMAP MF_00064

Gene names

Name:	cysD HAMAP MF_00064
Ordered Locus Names:	MSMEG_4979

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK69886.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	311 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064 SAAS SAAS002500
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity. HAMAP MF_00064
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily. HAMAP MF_00064

Ontologies

Keywords
Ligand	ATP-binding HAMAP MF_00064 SAAS SAAS002500 Nucleotide-binding
Molecular function	Nucleotidyltransferase HAMAP MF_00064 SAAS SAAS002500 EMBL ABK69886.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	sulfate assimilation Inferred from electronic annotation. Source: HAMAP sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0R242 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 6A69A0CEFE9A1760	FASTA	311	35,102
	10 20 30 40 50 60 MTAVDSAPAQ TRTGQYELSH LRALEAEAIH IIREVAAEFE RPVLLFSGGK DSIVMLHLAI 70 80 90 100 110 120 KAFAPGRLPF PVMHVDTGHN FEEVIATRDA LVEKHGLRLV VASVQDDIDA GRVVDNGPSR 130 140 150 160 170 180 NPLQTVTLLR GIRENKFDAA FGGARRDEEK ARAKERVFSF RDEFGQWDPK AQRPELWNIY 190 200 210 220 230 240 NGRHRKGEHI RVFPLSNWTE YDIWAYIGAE DITLPSIYYA HQRKVFGRDG MLLAVHEFMQ 250 260 270 280 290 300 PRDGEEVFET SVRFRTVGDV TCTGCVESTA ATVEQVIAET AVSRLTERGA TRADDRISEA 310 GMEDRKREGY F

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000480 Genomic DNA. Translation: ABK69886.1.
RefSeq	YP_889230.1. NC_008596.1.
3D structure databases
ProteinModelPortal	A0R242.
SMR	A0R242. Positions 17-220.
ModBase	Search...
Protein-protein interaction databases
STRING	A0R242.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000044808; EBMYCP00000043145; EBMYCG00000044803.
GeneID	4537710.
GenomeReviews	Gene locus MSMEG_4979 in contig CP000480_GR.
KEGG	msm:MSMEG_4979.
NMPDR	fig|246196.1.peg.4966.
PATRIC	18082257. VBIMycSme59918_4857.
TIGR	MSMEG_4979.
Phylogenomic databases
eggNOG	COG0175.
GeneTree	EBGT00050000016335.
HOGENOM	HBG758022.
OMA	ESAHIFR.
PhylomeDB	A0R242.
ProtClustDB	PRK05253.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0R242_MYCS2

Accession

Primary (citable) accession number: A0R242

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)