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A0R0W2 (A0R0W2_MYCS2) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoadenosine phosphosulfate reductase HAMAP MF_00063
EC=1.8.4.8 HAMAP MF_00063
Alternative name(s):
3'-phosphoadenylylsulfate reductase HAMAP MF_00063
PAPS reductase, thioredoxin dependent HAMAP MF_00063
PAPS sulfotransferase HAMAP MF_00063
PAdoPS reductase HAMAP MF_00063
Gene names
Name:cysH HAMAP MF_00063
Ordered Locus Names:MSMEG_4528
OrganismMycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK74710.1
Taxonomic identifier246196 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length236 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reduction of activated sulfate into sulfite By similarity. HAMAP MF_00063 SAAS SAAS002500

Catalytic activity

Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin. HAMAP MF_00063 SAAS SAAS002500

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3. HAMAP MF_00063 SAAS SAAS002500

Subcellular location

Cytoplasm By similarity HAMAP MF_00063 SAAS SAAS002500.

Sequence similarities

Belongs to the PAPS reductase family. CysH subfamily. HAMAP MF_00063

Sequences

Sequence LengthMass (Da)Tools
A0R0W2 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: 27267B9EF0E96746

FASTA23625,692
        10         20         30         40         50         60 
MTDVTTSTEN ELRELAERGA AELADASAEE LLRWTDEHFG GNYVVASNMQ DAVLVEMAAK 

        70         80         90        100        110        120 
VRPGVDVLFL DTGYHFAETI GTRDAVEAVY DVHVVNVTPE RTVAEQDELL GKNLFARDPG 

       130        140        150        160        170        180 
ECCRLRKVVP LTNALKGYSA WVTGIRRVEA PTRANAPLIS WDNAFGLVKI NPIAAWTDED 

       190        200        210        220        230 
MQNYIDANGI LVNPLVYEGY PSIGCAPCTS KPIPGADPRS GRWAGLSKTE CGLHVS

« Hide

References

[1]Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000480 Genomic DNA. Translation: ABK74710.1.
RefSeqYP_888800.1. NC_008596.1.

3D structure databases

ProteinModelPortalA0R0W2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0R0W2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000041505; EBMYCP00000039842; EBMYCG00000041500.
GeneID4534726.
GenomeReviewsGene locus MSMEG_4528 in contig CP000480_GR.
KEGGmsm:MSMEG_4528.
NMPDRfig|246196.1.peg.4521.
PATRIC18081383. VBIMycSme59918_4430.
TIGRMSMEG_4528.

Phylogenomic databases

eggNOGCOG0175.
GeneTreeEBGT00050000017137.
HOGENOMHBG758022.
OMAFEETLAY.
PhylomeDBA0R0W2.
ProtClustDBPRK02090.

Family and domain databases

HAMAPMF_00063. CysH.
[Tree]
InterProIPR011798. APS_reductase.
IPR004511. PAPS/APS_Rdtase.
IPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KOK00390.
PfamPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFPIRSF000857. PAPS_reductase. 1 hit.
TIGRFAMsTIGR02055. APS_reductase. 1 hit.
TIGR00434. CysH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA0R0W2_MYCS2
AccessionPrimary (citable) accession number: A0R0W2
Entry history
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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