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A0QYT4 (A0QYT4_MYCS2) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phenylalanine--tRNA ligase alpha chain HAMAP MF_00281
EC=6.1.1.20 HAMAP MF_00281
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha chain HAMAP MF_00281
Gene names
Name:pheS HAMAP MF_00281
Ordered Locus Names:MSMEG_3778
OrganismMycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK74870.1
Taxonomic identifier246196 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe). HAMAP MF_00281

Cofactor

Binds 2 magnesium ions per tetramer By similarity. HAMAP MF_00281

Subunit structure

Tetramer of two alpha and two beta chains By similarity. HAMAP MF_00281

Subcellular location

Cytoplasm By similarity HAMAP MF_00281.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily. HAMAP MF_00281

Sequences

Sequence LengthMass (Da)Tools
A0QYT4 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: 8718FA1F47082833

FASTA35638,905
        10         20         30         40         50         60 
MVRTQGGETA GEQPSDLSEE ALTKAVSAAR HAFDAAGDLD ALARAKTEHL GDRAPIALAR 

        70         80         90        100        110        120 
QALASLPKAD RADAGKRVNV ARAEAQRAYD ERLAVLRAER DAAVLVAERI DVTLPSTRQP 

       130        140        150        160        170        180 
LGARHPITIL AENIADTFVA MGWELAEGPE VETEQFNFDA LNFPPDHPAR SEQDTFQIAP 

       190        200        210        220        230        240 
DGSRQVLRTH TSPVQIRALL ERDLPVYIIS IGRTFRTDEL DSTHTPVFHQ VEGLAVDKGL 

       250        260        270        280        290        300 
TMAHLRGTLD AFARAQFGPE GRTRFRPHFF PFTEPSAEVD IWFPGKKGGP GWVEWGGCGM 

       310        320        330        340        350 
VNPNVLRACG IDPEVYSGFA FGMGLERTLQ FRNGIPDMRD MVEGDVRFSL PFGVGA

« Hide

References

[1]Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000480 Genomic DNA. Translation: ABK74870.1.
RefSeqYP_888072.1. NC_008596.1.

3D structure databases

ProteinModelPortalA0QYT4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0QYT4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000046108; EBMYCP00000044445; EBMYCG00000046103.
GeneID4532952.
GenomeReviewsGene locus MSMEG_3778 in contig CP000480_GR.
KEGGmsm:MSMEG_3778.
NMPDRfig|246196.1.peg.3784.
PATRIC18079949. VBIMycSme59918_3717.
TIGRMSMEG_3778.

Phylogenomic databases

eggNOGCOG0016.
GeneTreeEBGT00050000016426.
HOGENOMHBG284353.
OMAFRASYFP.
PhylomeDBA0QYT4.
ProtClustDBPRK00488.

Family and domain databases

HAMAPMF_00281. Phe_tRNA_synth_alpha1.
[Tree]
InterProIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_synth_II_N.
IPR022911. Phe_tRNA_synth_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
KOK01889.
PfamPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMSSF46589. tRNA_binding_arm. 1 hit.
TIGRFAMsTIGR00468. PheS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0QYT4_MYCS2
AccessionPrimary (citable) accession number: A0QYT4
Entry history
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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