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A0QYT2 (A0QYT2_MYCS2) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-acetyl-gamma-glutamyl-phosphate reductase HAMAP MF_00150
Short name=AGPR HAMAP MF_00150
EC=1.2.1.38 HAMAP MF_00150
Alternative name(s):
N-acetyl-glutamate semialdehyde dehydrogenase HAMAP MF_00150
Gene names
Name:argC HAMAP MF_00150
Ordered Locus Names:MSMEG_3776
OrganismMycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK73560.1
Taxonomic identifier246196 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH. HAMAP MF_00150 SAAS SAAS023013

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. HAMAP MF_00150 SAAS SAAS023013

Subcellular location

Cytoplasm By similarity HAMAP MF_00150 SAAS SAAS023013.

Sequence similarities

Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. HAMAP MF_00150

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1491 By similarity HAMAP MF_00150

Sequences

Sequence LengthMass (Da)Tools
A0QYT2 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: 12F78FD0DD527035

FASTA34334,845
        10         20         30         40         50         60 
MTSIAVAGAS GYAGGEILRL LLGHPAYADG RLTIGALTAA SSAGTTLGEH HPHLLPLADR 

        70         80         90        100        110        120 
VLESTDVEVL TGHDVVFLAL PHGHSAALAT QLGGTVIIDC GADFRLAEAA DWEKFYGSAH 

       130        140        150        160        170        180 
AGTWPYGLPE LPGGREALKG ATRIAVPGCY PTSALLALLP AVAAGLVEPN VTVVAVSGTS 

       190        200        210        220        230        240 
GAGKSAKVDL LGAEVIGSAR AYNVGGKHRH TPEIAQGLRK VTDKPVTVSF TPVLIPTSRG 

       250        260        270        280        290        300 
ILATCTAPTT ATEPEIRAAY EKAYGAEPFI HLLPEGQLPK TGSVIGSNAA QIQIAVDTEA 

       310        320        330        340 
KTLVAICAID NLTKGTGGAA VQSMNLALGW PETEGLSIVG VAP

« Hide

References

[1]Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000480 Genomic DNA. Translation: ABK73560.1.
RefSeqYP_888070.1. NC_008596.1.

3D structure databases

ProteinModelPortalA0QYT2.
SMRA0QYT2. Positions 2-343.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0QYT2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000042602; EBMYCP00000040939; EBMYCG00000042597.
GeneID4535285.
GenomeReviewsGene locus MSMEG_3776 in contig CP000480_GR.
KEGGmsm:MSMEG_3776.
NMPDRfig|246196.1.peg.3782.
PATRIC18079945. VBIMycSme59918_3715.
TIGRMSMEG_3776.

Phylogenomic databases

eggNOGCOG0002.
GeneTreeEBGT00050000015828.
HOGENOMHBG294213.
OMAVCRIAVH.
PhylomeDBA0QYT2.
ProtClustDBPRK00436.

Family and domain databases

HAMAPMF_00150. ArgC_type1.
[Tree]
InterProIPR023013. AGPR_AS.
IPR000706. AGPR_type-1.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
IPR012280. Semialdhyde_DH_dimer_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00145.
PfamPF01118. Semialdhyde_dh. 1 hit.
PF02774. Semialdhyde_dhC. 1 hit.
[Graphical view]
SMARTSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR01850. ArgC. 1 hit.
PROSITEPS01224. ARGC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0QYT2_MYCS2
AccessionPrimary (citable) accession number: A0QYT2
Entry history
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info