A0QYQ9 (A0QYQ9_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase HAMAP MF_00361
Short name=Poly(P)/ATP NAD kinase HAMAP MF_00361
EC=2.7.1.23 HAMAP MF_00361

Gene names

Name:	ppnK HAMAP MF_00361
Ordered Locus Names:	MSMEG_3750

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK73639.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361
Subcellular location	Cytoplasm By similarity HAMAP MF_00361.
Sequence similarities	Belongs to the NAD kinase family. HAMAP MF_00361

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00361
Ligand	ATP-binding HAMAP MF_00361 NAD HAMAP MF_00361 NADP HAMAP MF_00361 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00361 EMBL ABK73639.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QYQ9 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: D794A16D0E8F749E	FASTA	307	32,820
	10 20 30 40 50 60 MTVERSILLV VHTGRDEATE VARRVEKVLG DNGIGLRVLS AEAVDHGSVH LAPDEMRALG 70 80 90 100 110 120 VQIDVVDPDE RAAEGCELVL VLGGDGSFLR AAELARNVGI PVLGVNLGRI GFLAEAEAEA 130 140 150 160 170 180 IDMVLDHVIR RDYVVEERMT LDVAVRAHNE IISRGWALNE ASLEKGPRLG VLGVVLEVDG 190 200 210 220 230 240 RPVSAFGCDG VLVSTPTGST AYAFSAGGPV LWPDLEAILV VPNNAHALFA RPMVTSPEAC 250 260 270 280 290 300 IAIEVEAGGN DALVFCDGRR DMVVPAGGRL EVTRCGTPVK WVRLDSAPFT DRLVRKFRLP VTGWRGQ

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000480 Genomic DNA. Translation: ABK73639.1.
RefSeq	YP_888047.1. NC_008596.1.
3D structure databases
ProteinModelPortal	A0QYQ9.
SMR	A0QYQ9. Positions 2-305.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QYQ9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000047279; EBMYCP00000045616; EBMYCG00000047274.
GeneID	4534375.
GenomeReviews	Gene locus MSMEG_3750 in contig CP000480_GR.
KEGG	msm:MSMEG_3750.
NMPDR	fig|246196.1.peg.3757.
PATRIC	18079893. VBIMycSme59918_3692.
TIGR	MSMEG_3750.
Phylogenomic databases
eggNOG	COG0061.
GeneTree	EBGT00050000016530.
HOGENOM	HBG713904.
OMA	GPVVWPE.
PhylomeDB	A0QYQ9.
ProtClustDB	PRK03372.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. polyP/ATP_NADK_prd. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KO	K00858.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0QYQ9_MYCS2

Accession

Primary (citable) accession number: A0QYQ9

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)