A0QYQ0 (A0QYQ0_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cytidylate kinase HAMAP MF_00238
Short name=CK HAMAP MF_00238
EC=2.7.4.25 HAMAP MF_00238

Alternative name(s):
Cytidine monophosphate kinase HAMAP MF_00238

Gene names

Name:	cmk HAMAP MF_00238
Ordered Locus Names:	MSMEG_3739

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK70875.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily. HAMAP MF_00238

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00238
Ligand	ATP-binding HAMAP MF_00238 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00238 EMBL ABK70875.1 Transferase
Technical term	3D-structure PDB 3R20 Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pyrimidine nucleotide metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP cytidylate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QYQ0 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 475A7717297B1F29	FASTA	228	23,536
	10 20 30 40 50 60 MSGSLVVAVD GPAGTGKSSV SRGLARALGA RYLDTGAMYR IATLAVLRAG ADLTDPAAIE 70 80 90 100 110 120 KAAADAEIGV GSDPDVDAAF LAGEDVSSEI RGDAVTGAVS AVSAVPAVRT RLVDIQRKLA 130 140 150 160 170 180 TEGGRVVVEG RDIGTVVLPD ADVKIFLTAS AEERARRRNA QNVANGLPDD YATVLADVQR 190 200 210 220 RDHLDSTRPV SPLRAADDAL VVDTSDMDQA QVIAHLLDLV TAQAGARR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.
[2]	"Crystal structure of cytidylate kinase from Mycobacterium smegmatis." Seattle Structural Genomics Center for Infectious Disease (SSGCID) Edwards T.E., Clifton M.C., Sankaran B. Submitted (MAR-2011) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-228.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000480 Genomic DNA. Translation: ABK70875.1.

RefSeq

YP_888038.1. NC_008596.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3R20	X-ray	2.00	A	2-228	[»]

ProteinModelPortal

A0QYQ0.

ModBase

Search...

Protein-protein interaction databases

STRING

A0QYQ0.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

EBMYCT00000041875; EBMYCP00000040212; EBMYCG00000041870.

GeneID

4534682.

GenomeReviews

Gene locus MSMEG_3739 in contig CP000480_GR.

KEGG

msm:MSMEG_3739.

NMPDR

fig|246196.1.peg.3745.

PATRIC

18079869. VBIMycSme59918_3680.

TIGR

MSMEG_3739.

Phylogenomic databases

eggNOG

COG0283.

GeneTree

EBGT00050000015811.

HOGENOM

HBG354377.

OMA

DIGTVIC.

PhylomeDB

A0QYQ0.

ProtClustDB

PRK00023.

Family and domain databases

HAMAP

MF_00238. Cytidyl_kinase_type1.
[Tree]

InterPro

IPR003136. Cytidylate_kin.
IPR011994. Cytidylate_kinase_dom.
[Graphical view]

KO

K00945.

PANTHER

PTHR21299:SF2. Cytidylate_kin. 1 hit.

Pfam

PF02224. Cytidylate_kin. 1 hit.
[Graphical view]

TIGRFAMs

TIGR00017. Cmk. 1 hit.

ProtoNet

Search...

Entry information

Entry name

A0QYQ0_MYCS2

Accession

Primary (citable) accession number: A0QYQ0

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)