A0QYN5 (A0QYN5_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Pyrroloquinoline-quinone synthase HAMAP MF_00654
EC=1.3.3.11 HAMAP MF_00654

Alternative name(s):
Coenzyme PQQ synthesis protein C HAMAP MF_00654
Pyrroloquinoline quinone biosynthesis protein C HAMAP MF_00654

Gene names

Name:	pqqC HAMAP MF_00654
Ordered Locus Names:	MSMEG_3723

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK72494.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	238 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ By similarity. HAMAP MF_00654
Catalytic activity	6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H2O2 + 2 H2O. HAMAP MF_00654
Pathway	Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis. HAMAP MF_00654
Sequence similarities	Belongs to the pqqC family. HAMAP MF_00654

Ontologies

Keywords
Biological process	PQQ biosynthesis HAMAP MF_00654
Molecular function	Oxidoreductase HAMAP MF_00654
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pyrroloquinoline quinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	pyrroloquinoline-quinone synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QYN5 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 49EE5FADE2FAB478	FASTA	238	27,372
	10 20 30 40 50 60 MAPLARGAVT QALTPDEFEE ALREHVKDYH HLHPFHRRMN TGQCSPEEIR GWVANRFYYQ 70 80 90 100 110 120 VNIPRKDAAI LSTCPDREIR RRWVQRIIDH DGTTEGTGGI EAWLRLAEAV GLTRAEVEDA 130 140 150 160 170 180 RHLLPGVRFA VDAYVNFTRT RPWLEAVASS LTELFAPDLM AERLAAFERH YTWIDPKELS 190 200 210 220 230 YFRSRITQAP RDSEHGLEVV RRHCVTQETQ TAALSALSFK CDVLWSMLDA IDQAYGNR

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000480 Genomic DNA. Translation: ABK72494.1.
RefSeq	YP_888023.1. NC_008596.1.
3D structure databases
ProteinModelPortal	A0QYN5.
SMR	A0QYN5. Positions 9-236.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QYN5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000042153; EBMYCP00000040490; EBMYCG00000042148.
GeneID	4535189.
GenomeReviews	Gene locus MSMEG_3723 in contig CP000480_GR.
KEGG	msm:MSMEG_3723.
NMPDR	fig|246196.1.peg.3730.
PATRIC	18079843. VBIMycSme59918_3668.
TIGR	MSMEG_3723.
Phylogenomic databases
eggNOG	COG5424.
HOGENOM	HBG288944.
OMA	DSWPQHY.
ProtClustDB	PRK05157.
Family and domain databases
HAMAP	MF_00654. PQQ_syn_PqqC. [Tree]
InterPro	IPR016084. Haem_Oase-like_multi-hlx. IPR011845. PQQ_synth_PqqC. IPR004305. TENA/THI4/PQQ_synthPqqC_dom. [Graphical view]
Gene3D	G3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.
KO	K06137.
Pfam	PF03070. TENA_THI-4. 1 hit. [Graphical view]
SUPFAM	SSF48613. Heme_oxygenase. 1 hit.
TIGRFAMs	TIGR02111. PQQ_syn_pqqC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0QYN5_MYCS2

Accession

Primary (citable) accession number: A0QYN5

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)