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Protein
Submitted name:

Enhanced intracellular survival protein

Gene

eis

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei26 – 261Coenzyme ACombined sources
Binding sitei258 – 2581Coenzyme ACombined sources

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-3513-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Enhanced intracellular survival proteinImported
Submitted name:
Enhanced intracellular survival protein EisImported
Gene namesi
Name:eisImported
Ordered Locus Names:MSMEG_3513Imported, MSMEI_3433Imported
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000006158 Componenti: Chromosome
  • UP000000757 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi246196.MSMEG_3513.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3SXNX-ray2.03A/B/C/D/E/F1-402[»]
4QB9X-ray3.29A/B/C/D/E/F1-402[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 166162N-acetyltransferaseInterPro annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni85 – 873Coenzyme A bindingCombined sources
Regioni93 – 986Coenzyme A bindingCombined sources
Regioni121 – 1288Coenzyme A bindingCombined sources

Phylogenomic databases

eggNOGiENOG4105HHS. Bacteria.
COG4552. LUCA.
HOGENOMiHOG000244829.
OMAiAYIALWR.
OrthoDBiEOG63FVZT.

Family and domain databases

Gene3Di3.30.1050.10. 1 hit.
3.40.630.30. 2 hits.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR025559. Eis_dom.
IPR000182. GNAT_dom.
IPR003033. SCP2_sterol-bd_dom.
[Graphical view]
PfamiPF13530. SCP2_2. 1 hit.
[Graphical view]
SUPFAMiSSF55718. SSF55718. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0QY29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITPRTLHTI TDDDWTRIAL LARFAFGDIE PEQTQAAWRS MVPEDATVVV
60 70 80 90 100
PDETDDAFVG QSLYLDMQLT VPGGEVLPVA GISFVAVAPT HRRRGVLRAM
110 120 130 140 150
YTELHDRIAR AGYPLAVLTA SEGGIYGRFG YGVATIEQHV SVDRRLAQFH
160 170 180 190 200
PAAPDPGGVR MLVPADHRDG LADIYDRWRR RTPGGLVRPD ALWDDLLADR
210 220 230 240 250
PESRRGGGEL FAFGHQDGYA LYRVDRGPDG RRSAHVVELT AVTADAHAAL
260 270 280 290 300
WRALLGLDLI DRVSIGTHPH DPLPYLLTDP RQAQVTASAD DLWIRIMNVP
310 320 330 340 350
AALEARRYQA DLDVVLDVAD GFRSDGGRFA LQISGGRARC TTTDAPADIE
360 370 380 390 400
IDLDVLGGLY LGAHRVDGFA AANRLRSKDS ELLQQFGAAF AGDMPAELGY

GF
Length:402
Mass (Da):43,909
Last modified:January 9, 2007 - v1
Checksum:i0DFB90E2597372E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK75645.1.
CP001663 Genomic DNA. Translation: AFP39896.1.
RefSeqiWP_011729122.1. NZ_CP009494.1.
YP_887817.1. NC_008596.1.

Genome annotation databases

EnsemblBacteriaiABK75645; ABK75645; MSMEG_3513.
AFP39896; AFP39896; MSMEI_3433.
GeneIDi4534906.
KEGGimsb:LJ00_17480.
msg:MSMEI_3433.
msm:MSMEG_3513.
PATRICi18079439. VBIMycSme59918_3466.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK75645.1.
CP001663 Genomic DNA. Translation: AFP39896.1.
RefSeqiWP_011729122.1. NZ_CP009494.1.
YP_887817.1. NC_008596.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3SXNX-ray2.03A/B/C/D/E/F1-402[»]
4QB9X-ray3.29A/B/C/D/E/F1-402[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246196.MSMEG_3513.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK75645; ABK75645; MSMEG_3513.
AFP39896; AFP39896; MSMEI_3433.
GeneIDi4534906.
KEGGimsb:LJ00_17480.
msg:MSMEI_3433.
msm:MSMEG_3513.
PATRICi18079439. VBIMycSme59918_3466.

Phylogenomic databases

eggNOGiENOG4105HHS. Bacteria.
COG4552. LUCA.
HOGENOMiHOG000244829.
OMAiAYIALWR.
OrthoDBiEOG63FVZT.

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-3513-MONOMER.

Family and domain databases

Gene3Di3.30.1050.10. 1 hit.
3.40.630.30. 2 hits.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR025559. Eis_dom.
IPR000182. GNAT_dom.
IPR003033. SCP2_sterol-bd_dom.
[Graphical view]
PfamiPF13530. SCP2_2. 1 hit.
[Graphical view]
SUPFAMiSSF55718. SSF55718. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.
  2. Hayward D., Fahey B.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  3. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
    Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.M.
    Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  4. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
    Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
    Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.

Entry informationi

Entry nameiA0QY29_MYCS2
AccessioniPrimary (citable) accession number: A0QY29
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: May 11, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.