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Protein

N-acetyltransferase Eis

Gene

eis

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei26Coenzyme ACombined sources1
Active sitei126Proton donorUniRule annotation1
Binding sitei258Coenzyme ACombined sources1
Active sitei402Proton acceptor; via carboxylateUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
N-acetyltransferase EisUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
Name:eisUniRule annotation
Ordered Locus Names:MSMEG_3513Imported
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000757 Componenti: Chromosome

Interactioni

Subunit structurei

Homohexamer; trimer of dimers.UniRule annotation

Protein-protein interaction databases

STRINGi246196.MSMEG_3513.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3SXNX-ray2.03A/B/C/D/E/F1-402[»]
4QB9X-ray3.29A/B/C/D/E/F1-402[»]
SMRiA0QY29.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni85 – 87Acetyl-CoA bindingUniRule annotation3
Regioni85 – 87Coenzyme A bindingCombined sources3
Regioni93 – 98Acetyl-CoA bindingUniRule annotation6
Regioni93 – 98Coenzyme A bindingCombined sources6
Regioni121 – 128Coenzyme A bindingCombined sources8
Regioni121 – 122Acetyl-CoA bindingUniRule annotation2

Sequence similaritiesi

Belongs to the acetyltransferase Eis family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105HHS. Bacteria.
COG4552. LUCA.
HOGENOMiHOG000244829.
OMAiAYIALWR.
OrthoDBiPOG091H0ZD3.

Family and domain databases

Gene3Di3.30.1050.10. 1 hit.
HAMAPiMF_01812. UPF0256. 1 hit.
InterProiView protein in InterPro
IPR016181. Acyl_CoA_acyltransferase.
IPR025559. Eis_dom.
IPR000182. GNAT_dom.
IPR022902. NAcTrfase_Eis.
IPR003033. SCP2_sterol-bd_dom.
PfamiView protein in Pfam
PF13530. SCP2_2. 1 hit.
SUPFAMiSSF55718. SSF55718. 1 hit.
SSF55729. SSF55729. 1 hit.
PROSITEiView protein in PROSITE
PS51186. GNAT. 1 hit.

Sequencei

Sequence statusi: Complete.

A0QY29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITPRTLHTI TDDDWTRIAL LARFAFGDIE PEQTQAAWRS MVPEDATVVV
60 70 80 90 100
PDETDDAFVG QSLYLDMQLT VPGGEVLPVA GISFVAVAPT HRRRGVLRAM
110 120 130 140 150
YTELHDRIAR AGYPLAVLTA SEGGIYGRFG YGVATIEQHV SVDRRLAQFH
160 170 180 190 200
PAAPDPGGVR MLVPADHRDG LADIYDRWRR RTPGGLVRPD ALWDDLLADR
210 220 230 240 250
PESRRGGGEL FAFGHQDGYA LYRVDRGPDG RRSAHVVELT AVTADAHAAL
260 270 280 290 300
WRALLGLDLI DRVSIGTHPH DPLPYLLTDP RQAQVTASAD DLWIRIMNVP
310 320 330 340 350
AALEARRYQA DLDVVLDVAD GFRSDGGRFA LQISGGRARC TTTDAPADIE
360 370 380 390 400
IDLDVLGGLY LGAHRVDGFA AANRLRSKDS ELLQQFGAAF AGDMPAELGY

GF
Length:402
Mass (Da):43,909
Last modified:January 9, 2007 - v1
Checksum:i0DFB90E2597372E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK75645.1.
RefSeqiWP_011729122.1. NZ_CP009494.1.
YP_887817.1. NC_008596.1.

Genome annotation databases

EnsemblBacteriaiABK75645; ABK75645; MSMEG_3513.
AFP39896; AFP39896; MSMEI_3433.
GeneIDi4534906.
KEGGimsb:LJ00_17480.
msm:MSMEG_3513.
PATRICifig|246196.19.peg.3466.

Similar proteinsi

Entry informationi

Entry nameiA0QY29_MYCS2
AccessioniPrimary (citable) accession number: A0QY29
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: September 27, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported