A0QX55 (A0QX55_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III alpha subunit EMBL ABK72022.1
EC=2.7.7.7 EMBL ABK72022.1

Gene names

Ordered Locus Names:

MSMEG_3178

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK72022.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	1184 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QX55 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 644ED0238072CA06	FASTA	1,184	129,207
	10 20 30 40 50 60 MSGTDGRSSG SFVHLHNHTE YSMLDGAAKI TPMLAEAQRL EMPAIGMTDH GNMFGASEFY 70 80 90 100 110 120 NSATKAGIKP IIGIEAYIAP GSRFDTKRVT WGDPGQKGDD VSGSGAYTHM TMVAENATGL 130 140 150 160 170 180 RNLFKLSSLA SFEGQLGKWS RMDAEIIAEH AEGIIATTGC PSGEVQTRLR LGHEREALEA 190 200 210 220 230 240 AAKWREIFGP ENFFLELMDH GLDIERRVRE GLLEIGRKLG IPPLATNDCH YVTREAARNH 250 260 270 280 290 300 EALLCVQTGK TLSDPTRFKF DGDGYFLKSA EEMRALWDSQ VPGACDSTLL IGERVQSYAD 310 320 330 340 350 360 VWEPRDRMPV FPVPEGHDQA SWLTHEVKAG LERRFRGGPV PEEYTTRAEY EIKVICDKGF 370 380 390 400 410 420 PSYFLIVADL INYARSVGIR VGPGRGSAAG SLVAYALGIT NIDPIPHGLL FERFLNPERP 430 440 450 460 470 480 SAPDIDIDFD DRRRGEMLRY AANRWGSERV AQVITFGTIK TKAALKDSAR VNFGQPGFAI 490 500 510 520 530 540 ADRITKALPP PIMAKDIPLS GITDPNHERY KEAAEVRGLI DTDPDVRTIY ETARGLEGLV 550 560 570 580 590 600 RNAGVHACAV IMSSEPLIDA IPLWKRPQDG AIITGWDYPS CEAIGLLKMD FLGLRNLTII 610 620 630 640 650 660 GDAIANIKAN RGIDLDLETL PLDDPAAYEL LSRGDTLGVF QLDGGPMRDL LRRMQPTGFN 670 680 690 700 710 720 DIVAVLALYR PGPMGMNAHN DYADRKNGRQ PIKPIHPELE EPLKDILAET YGLIVYQEQI 730 740 750 760 770 780 MFIAQKVASY TMGKADALRK AMGKKKLEVL EAEYKGFKEG MTANGFSEGA VKALWDTILP 790 800 810 820 830 840 FAGYAFNKSH AAGYGLVSYW TAYLKANYPA EYMAGLLTSV GDDKDKAAVY LADCRRLGIT 850 860 870 880 890 900 VLPPDVNESE HNFASVGDDI RFGLGAIRNV GANVVSSLIK TRTEKGKFTD FSDYLNKIDI 910 920 930 940 950 960 TACNKKVTES LIKAGAFDSL GHPRKGLFLV HTDAVDSVLG TKKAEAMGQF DLFGGGEDTG 970 980 990 1000 1010 1020 TDAVFTIKVP DEEWEDKHKL ALEREMLGLY VSGHPLNGVA HLLANQVDTQ IPAILDGDVA 1030 1040 1050 1060 1070 1080 NDAQVLVGGI LASVNRRVNK NGLPWASAQL EDLTGGIEVL FFPQTYSLFG ADIADDVVVL 1090 1100 1110 1120 1130 1140 VKAKVAARDD RIALIAHELI VPDFSSAQAD RPLSVSLPTR QCTIDKVTAL KQVLANHPGT 1150 1160 1170 1180 SQVHLRLISG ERITTLELDQ SLRVTPSSAL MGDLKALLGP GCLG

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000480 Genomic DNA. Translation: ABK72022.1.
RefSeq	YP_887493.1. NC_008596.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A0QX55.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000045673; EBMYCP00000044010; EBMYCG00000045668.
GeneID	4532730.
GenomeReviews	Gene locus MSMEG_3178 in contig CP000480_GR.
KEGG	msm:MSMEG_3178.
NMPDR	fig|246196.1.peg.3185.
PATRIC	18078782. VBIMycSme59918_3139.
TIGR	MSMEG_3178.
Phylogenomic databases
eggNOG	COG0587.
GeneTree	EBGT00050000016568.
HOGENOM	HBG734490.
OMA	RVLQMPY.
ProtClustDB	PRK05673.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0QX55_MYCS2

Accession

Primary (citable) accession number: A0QX55

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)