A0QWS9 (A0QWS9_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Guanylate kinase EMBL ABK70923.1
EC=2.7.4.8 EMBL ABK70923.1

Gene names

Ordered Locus Names:

MSMEG_3051

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK70923.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	200 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Essential for recycling GMP and indirectly, cGMP By similarity. SAAS SAAS020590
Catalytic activity	ATP + GMP = ADP + GDP. SAAS SAAS020590
Subcellular location	Cytoplasm By similarity SAAS SAAS020590.
Sequence similarities	Contains 1 guanylate kinase-like domain. SAAS SAAS017665

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS020590
Ligand	ATP-binding SAAS SAAS020590 Nucleotide-binding
Molecular function	Kinase SAAS SAAS020590 EMBL ABK70923.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	purine nucleotide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW guanylate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QWS9 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 061B2CA097CA4AF6	FASTA	200	21,589
	10 20 30 40 50 60 MTVGRGAGQR ATDGPARARV VVLSGPSAVG KSTVVRCLRE RLPDLYFSVS VTTRAPRPGE 70 80 90 100 110 120 VDGVDYTFVS PERFQQLIDD GELLEWAEIH GGLHRSGTPA APVREATRAG RPVLIEVDLA 130 140 150 160 170 180 GARAVKQAMP EVVSVFLAPP SWDELVRRLS GRGTETPEVM ARRLDTARAE MAAQSDFDRV 190 200 VVNRQLDSAC AELVSLLVDS

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000480 Genomic DNA. Translation: ABK70923.1.
RefSeq	YP_887367.1. NC_008596.1.
3D structure databases
ProteinModelPortal	A0QWS9.
SMR	A0QWS9. Positions 18-198.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QWS9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000041897; EBMYCP00000040234; EBMYCG00000041892.
GeneID	4534268.
GenomeReviews	Gene locus MSMEG_3051 in contig CP000480_GR.
KEGG	msm:MSMEG_3051.
NMPDR	fig|246196.1.peg.3064.
PATRIC	18078528. VBIMycSme59918_3012.
TIGR	MSMEG_3051.
Phylogenomic databases
eggNOG	COG0194.
GeneTree	EBGT00050000017746.
HOGENOM	HBG671982.
OMA	EWAEFAG.
PhylomeDB	A0QWS9.
ProtClustDB	PRK00300.
Family and domain databases
HAMAP	MF_00328. Guanylate_kinase. [Tree]
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR017665. Guanylate_kinase_sub. [Graphical view]
KO	K00942.
Pfam	PF00625. Guanylate_kin. 1 hit. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
TIGRFAMs	TIGR03263. Guanyl_kin. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0QWS9_MYCS2

Accession

Primary (citable) accession number: A0QWS9

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)