A0QWJ0 (A0QWJ0_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
4-aminobutyrate aminotransferase EMBL AFP39349.1
EC=2.6.1.19 EMBL AFP39349.1

Submitted name:
4-aminobutyrate transaminase EMBL ABK73007.1
EC=2.6.1.19 EMBL ABK73007.1

Gene names

Name:	gabT EMBL ABK73007.1
Ordered Locus Names:	MSMEG_2959 EMBL ABK73007.1, MSMEI_2885 EMBL AFP39349.1

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [Reference proteome] [HAMAP] EMBL ABK73007.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium smegmatis

Protein attributes

Sequence length	446 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. RuleBase RU003560

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU003560
Molecular function	Aminotransferase EMBL ABK73007.1 Transferase
Technical term	3D-structure PDB 3OKS Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	gamma-aminobutyric acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	4-aminobutyrate transaminase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QWJ0 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 5B94FA8EBC07306A	FASTA	446	46,926
	10 20 30 40 50 60 MSHPEQSRHL ATAIPGPRSQ ALIDRKGTAV ARGVGTTMPV YAVRAGGGIV EDVDGNRLID 70 80 90 100 110 120 LGSGIAVTTV GNSAPKVVEA VRSQVGDFTH TCFMVTPYEG YVAVCEQLNR LTPVRGDKRS 130 140 150 160 170 180 ALFNSGSEAV ENAVKIARSH THKPAVVAFD HAYHGRTNLT MALTAKVMPY KDGFGPFAPE 190 200 210 220 230 240 IYRAPLSYPF RDAEFGKELA TDGELAAKRA ITVIDKQIGA DNLAAVVIEP IQGEGGFIVP 250 260 270 280 290 300 ADGFLPTLLD WCRKNDVVFI ADEVQTGFAR TGAMFACEHE GIDPDLIVTA KGIAGGLPLS 310 320 330 340 350 360 AVTGRAEIMD SPHVSGLGGT YGGNPIACAA ALATIETIES EGLVARAQQI EKIMKDRLGR 370 380 390 400 410 420 LQAEDDRIGD VRGRGAMIAM ELVKAGTTEP DADLTKALCA GAHAAGVIVL SCGTYGNVVR 430 440 FLPPLSIGDD LLNEGLDVLE EVLRGA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"ICDS database: interrupted CoDing sequences in prokaryotic genomes." Perrodou E., Deshayes C., Muller J., Schaeffer C., Van Dorsselaer A., Ripp R., Poch O., Reyrat J.M., Lecompte O. Nucleic Acids Res. 34:D338-D343(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: MC2 155 EMBL AFP39349.1.
[2]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155 and MC2 155 EMBL ABK73007.1.
[3]	"Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?" Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.M. Genome Biol. 8:R20-R20(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155 and MC2 155 EMBL AFP39349.1.
[4]	"Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol." Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O. Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155 and MC2 155 EMBL AFP39349.1.
[5]	"Crystal structure of 4-aminobutyrate transaminase from mycobacterium smegmatis." Gardberg A., Sankaran B., Abendroth J., Staker B., SSGCID Submitted (AUG-2010) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 2-446.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000480 Genomic DNA. Translation: ABK73007.1.
CP001663 Genomic DNA. Translation: AFP39349.1.

RefSeq

YP_006567644.1. NC_018289.1.
YP_887278.1. NC_008596.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3OKS	X-ray	1.80	A/B/C/D	2-446	[»]

ModBase

Search...

Protein-protein interaction databases

STRING

246196.MSMEG_2959.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

ABK73007; ABK73007; MSMEG_2959.
AFP39349; AFP39349; MSMEI_2885.

GeneID

13425252.
4532510.

KEGG

msg:MSMEI_2885.
msm:MSMEG_2959.

PATRIC

18078348. VBIMycSme59918_2922.

Phylogenomic databases

eggNOG

COG0160.

HOGENOM

HOG000020206.

KO

K07250.

OMA

PGTHEKR.

ProtClustDB

PRK06058.

Enzyme and pathway databases

BioCyc

MSME246196:GJ4Y-2959-MONOMER.

Family and domain databases

Gene3D

3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.

InterPro

IPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]

PANTHER

PTHR11986. PTHR11986. 1 hit.

Pfam

PF00202. Aminotran_3. 1 hit.
[Graphical view]

SUPFAM

SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.

TIGRFAMs

TIGR00700. GABAtrnsam. 1 hit.

PROSITE

PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

A0QWJ0.

Entry information

Entry name

A0QWJ0_MYCS2

Accession

Primary (citable) accession number: A0QWJ0

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)