Reviewed, UniProtKB/Swiss-Prot A0QVL2 (MQO_MYCS2)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	MSMEG_2613

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) [Complete proteome] [HAMAP]

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	510 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 510	510	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000325501

Sequences

	Sequence		Length	Mass (Da)
	A0QVL2-1 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 5B7D1BA26DDFBAF3	FASTA	510	54,914
	10 20 30 40 50 60 MSEANAGTNA KTDVVLVGAG IMSATLGTLI KLLEPNWSIT MIERLDGAAA ESSDPWNNAG 70 80 90 100 110 120 TGHSALCELN YTPALPDGTI DISKAVNVNE QFQVSRQFWA HAVENGVLPD VRSFLNPVPH 130 140 150 160 170 180 VSFVYGADNV QYLKARYNAL VTNPLFASME FIDDKDEFTR RLPLMAEKRD FSEPVALNWS 190 200 210 220 230 240 QHGTDVDFGS LSRQLIGFAA GNGMTTMFGH DVRDLSKNSD GSWTVKVRNR RTGNNFKINA 250 260 270 280 290 300 KFVFVGAGGG ALPLLQKSGI PEAKGFGGFP VGGAFLRTNK QHLTSRHNAK VYGLPPLGAP 310 320 330 340 350 360 PMSVPHLDTR VINGRQWLLF GPFAGWSPKF LKQGKVTDLP LSVKPNNLAS MLGVGLTEVG 370 380 390 400 410 420 LLKYLIGQLL LSEPARVETL REFAPSAVDS DWELDIAGQR VQVIRRKGAG GVLEFGTTVL 430 440 450 460 470 480 AAADGSIAGL LGASPGASTA VPAMLDVLQR CFADRYQAWT PKLKEMVPSL GTKLSDEPKL 490 500 510 FEEVWSWGTK VLKLDVQANT AEAANAPATV

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000480 Genomic DNA. Translation: ABK72231.1.
RefSeq	YP_886950.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4534593.
GenomeReviews	Gene locus MSMEG_2613 in contig CP000480_GR.
KEGG	msm:MSMEG_2613.
NMPDR	fig|246196.1.peg.2614.
TIGR	MSMEG_2613.
Phylogenomic databases
OMA	A0QVL2. HLAKAYG.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_MYCS2

Accession

Primary (citable) accession number: A0QVL2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	January 9, 2007
Last modified:	June 16, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)