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A0QV88

- A0QV88_MYCS2

UniProt

A0QV88 - A0QV88_MYCS2

Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

MSMEG_2487

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 1 (09 Jan 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. 4-aminobutyrate transaminase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    Keywords - Molecular functioni

    AminotransferaseImported, Transferase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciMSME246196:GJ4Y-2487-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    4-aminobutyrate aminotransferaseImported (EC:2.6.1.19Imported)
    Submitted name:
    AminotransferaseImported (EC:2.6.1.19Imported)
    Gene namesi
    Ordered Locus Names:MSMEG_2487Imported, MSMEI_2427Imported
    OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
    Taxonomic identifieri246196 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000006158: Chromosome, UP000000757: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi246196.MSMEG_2487.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0160.
    HOGENOMiHOG000020206.
    KOiK00823.
    OMAiQNDLAMA.
    OrthoDBiEOG6QVRHN.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view]
    PANTHERiPTHR11986. PTHR11986. 1 hit.
    PfamiPF00202. Aminotran_3. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMiSSF53383. SSF53383. 1 hit.
    PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0QV88-1 [UniParc]FASTAAdd to Basket

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    MTELSQALKQ ATGVIAARGE GVLLYDEQDR RYLDFTAGIG VTSTGHCHPR    50
    VVEAAQRQVG TLIHGQYTTV MHRPLLTLVE RLGEVLPAGL DRMFFANSGS 100
    EAIEAALRLS RQATGRPNVI VFHGGFHGRT VAAASMTTSG TKFRSGFSPL 150
    MAGVHVSPFP DPTHFGWPVE QTTDFALSQL DYVLQTVSAP ADTAAFFVEP 200
    VLGEGGYVPA NERFLAGLRE RADAHGILLV LDEVQTGYGR TGKFWGGEHF 250
    DAKPDILVTA KGLASGFPLS GIAASSELMA KAWPGSQGGT YGANAVACAA 300
    AIATLDVIAD ENLVANAAER GAQLKQALQT VADKHEQITD VRGLGLMIGN 350
    EFRDADGKPD GTTAAAVQQE AARRGLLLLT CGAWGQVVRF IPALVVSADE 400
    VEEAAGIWAD AVSAVVS 417
    Length:417
    Mass (Da):43,922
    Last modified:January 9, 2007 - v1
    Checksum:i28756732FA1A644D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000480 Genomic DNA. Translation: ABK71148.1.
    CP001663 Genomic DNA. Translation: AFP38895.1.
    RefSeqiYP_006567190.1. NC_018289.1.
    YP_886826.1. NC_008596.1.

    Genome annotation databases

    EnsemblBacteriaiABK71148; ABK71148; MSMEG_2487.
    AFP38895; AFP38895; MSMEI_2427.
    GeneIDi4533529.
    KEGGimsg:MSMEI_2427.
    msm:MSMEG_2487.
    PATRICi18077400. VBIMycSme59918_2452.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000480 Genomic DNA. Translation: ABK71148.1 .
    CP001663 Genomic DNA. Translation: AFP38895.1 .
    RefSeqi YP_006567190.1. NC_018289.1.
    YP_886826.1. NC_008596.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 246196.MSMEG_2487.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK71148 ; ABK71148 ; MSMEG_2487 .
    AFP38895 ; AFP38895 ; MSMEI_2427 .
    GeneIDi 4533529.
    KEGGi msg:MSMEI_2427.
    msm:MSMEG_2487.
    PATRICi 18077400. VBIMycSme59918_2452.

    Phylogenomic databases

    eggNOGi COG0160.
    HOGENOMi HOG000020206.
    KOi K00823.
    OMAi QNDLAMA.
    OrthoDBi EOG6QVRHN.

    Enzyme and pathway databases

    BioCyci MSME246196:GJ4Y-2487-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR005814. Aminotrans_3.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    [Graphical view ]
    PANTHERi PTHR11986. PTHR11986. 1 hit.
    Pfami PF00202. Aminotran_3. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MC2 155Imported.
    2. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
      Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700084 / mc(2)155 and MC2 155Imported.
    3. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
      Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.
      Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
    4. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
      Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
      Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700084 / mc(2)155 and MC2 155.

    Entry informationi

    Entry nameiA0QV88_MYCS2
    AccessioniPrimary (citable) accession number: A0QV88
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 9, 2007
    Last sequence update: January 9, 2007
    Last modified: October 1, 2014
    This is version 59 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3