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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

MSMEG_2487

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-2487-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported (EC:2.6.1.19Imported)
Submitted name:
AminotransferaseImported (EC:2.6.1.19Imported)
Submitted name:
Mycobacterium smegmatis str. MC2 155, complete genomeImported
Gene namesi
Ordered Locus Names:MSMEG_2487Imported, MSMEI_2427Imported
ORF Names:LJ00_12380Imported
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000006158 Componenti: Chromosome UP000000757 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi246196.MSMEG_2487.

Structurei

3D structure databases

ProteinModelPortaliA0QV88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK00823.
OMAiGNTAFFQ.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0QV88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTELSQALKQ ATGVIAARGE GVLLYDEQDR RYLDFTAGIG VTSTGHCHPR
60 70 80 90 100
VVEAAQRQVG TLIHGQYTTV MHRPLLTLVE RLGEVLPAGL DRMFFANSGS
110 120 130 140 150
EAIEAALRLS RQATGRPNVI VFHGGFHGRT VAAASMTTSG TKFRSGFSPL
160 170 180 190 200
MAGVHVSPFP DPTHFGWPVE QTTDFALSQL DYVLQTVSAP ADTAAFFVEP
210 220 230 240 250
VLGEGGYVPA NERFLAGLRE RADAHGILLV LDEVQTGYGR TGKFWGGEHF
260 270 280 290 300
DAKPDILVTA KGLASGFPLS GIAASSELMA KAWPGSQGGT YGANAVACAA
310 320 330 340 350
AIATLDVIAD ENLVANAAER GAQLKQALQT VADKHEQITD VRGLGLMIGN
360 370 380 390 400
EFRDADGKPD GTTAAAVQQE AARRGLLLLT CGAWGQVVRF IPALVVSADE
410
VEEAAGIWAD AVSAVVS
Length:417
Mass (Da):43,922
Last modified:January 9, 2007 - v1
Checksum:i28756732FA1A644D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK71148.1.
CP001663 Genomic DNA. Translation: AFP38895.1.
CP009494 Genomic DNA. Translation: AIU07668.1.
RefSeqiWP_011728377.1. NC_018289.1.
YP_006567190.1. NC_018289.1.
YP_886826.1. NC_008596.1.

Genome annotation databases

EnsemblBacteriaiABK71148; ABK71148; MSMEG_2487.
AFP38895; AFP38895; MSMEI_2427.
AIU07668; AIU07668; LJ00_12380.
GeneIDi4533529.
KEGGimsm:MSMEG_2487.
PATRICi18077400. VBIMycSme59918_2452.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK71148.1.
CP001663 Genomic DNA. Translation: AFP38895.1.
CP009494 Genomic DNA. Translation: AIU07668.1.
RefSeqiWP_011728377.1. NC_018289.1.
YP_006567190.1. NC_018289.1.
YP_886826.1. NC_008596.1.

3D structure databases

ProteinModelPortaliA0QV88.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246196.MSMEG_2487.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK71148; ABK71148; MSMEG_2487.
AFP38895; AFP38895; MSMEI_2427.
AIU07668; AIU07668; LJ00_12380.
GeneIDi4533529.
KEGGimsm:MSMEG_2487.
PATRICi18077400. VBIMycSme59918_2452.

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK00823.
OMAiGNTAFFQ.
OrthoDBiEOG6QVRHN.

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-2487-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.
  2. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  3. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
    Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.
    Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  4. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
    Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
    Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155 and MC2 155.
  5. "Complete Genome Sequences of a Mycobacterium smegmatis Laboratory Strain (MC2 155) and Isoniazid-Resistant (4XR1/R2) Mutant Strains."
    Mohan A., Padiadpu J., Baloni P., Chandra N.
    Genome Announc. 3:0-0(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.

Entry informationi

Entry nameiA0QV88_MYCS2
AccessioniPrimary (citable) accession number: A0QV88
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: May 27, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.