A0QV29 (A0QV29_MYCS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase HAMAP MF_00277
Short name=PII uridylyl-transferase HAMAP MF_00277
EC=2.7.7.59 HAMAP MF_00277

Alternative name(s):
UTase HAMAP MF_00277
Uridylyl-removing enzyme HAMAP MF_00277

Gene names

Name:	glnD HAMAP MF_00277
Ordered Locus Names:	MSMEG_2427

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK73395.1

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	824 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277 SAAS SAAS002912
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277 SAAS SAAS002912
Sequence similarities	Belongs to the glnD family. HAMAP MF_00277

Ontologies

Keywords
Molecular function	Nucleotidyltransferase HAMAP MF_00277 SAAS SAAS002912 EMBL ABK73395.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QV29 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 3D464C4DD96D5E2F	FASTA	824	88,251
	10 20 30 40 50 60 MAEHKTQSAG ASHKGAPAGS SRPANDLAAA VSQLLTGGPR QLDSAALRDA LLDLYEFWLT 70 80 90 100 110 120 TKATELGITA DSGFAIVATG GLGRGEMLPY SDLDLMLLHD NMPVDVVTEV AEKLWYPLWD 130 140 150 160 170 180 ANIRLDHSVR TVPEALKVAG EDISVGLAML DVRHIAGDAD LSSLLVGGAR RQWRIGIASR 190 200 210 220 230 240 FEELVEHAQA RWQRSGQIAH RAEPDLKSGR GGLRDVQLLN ALAIAQLADV YPSRALASPT 250 260 270 280 290 300 GTLGGAHLAL LNVRTELHRV SGRGRELLLA QHADEIGAAL RIGDRFDLAR MLSDAARTVS 310 320 330 340 350 360 YYVDSGIRTA ANALPRRGFA ALRRPVRRPL DEGVIEFAGE VILARDARPE RDPGLVLRVA 370 380 390 400 410 420 AASATTGLPI AVSTLSRLAE TAPELRTPWP SQALKDLLVL LAAGPAAVAT IEALDRTGLW 430 440 450 460 470 480 GRLFPEWGAV RDLPPRDVVH IWTVDRHLVE TVSRASAFTT RVSRPDLLLL GALCHDIGKG 490 500 510 520 530 540 RGGDHSVIGA ELATQIGTRL GLWPSDIDVL SKLVRYHLLL PETATRRDLQ DPKTIAAVVD 550 560 570 580 590 600 ALGGDMVVLE LLDVLAEADS LATGPGVWGD WKASLIGDLV RRCRLVMAGE PLPHPDPIDP 610 620 630 640 650 660 RFLEIAADVG VHVELTPGDG QHIFNVTMIA PDRRGLLSKA AGVLALNSLR VHSASVNSHE 670 680 690 700 710 720 GSAINTFVVS PHFGSPPAAD LLRQQFVLAL DGDLDVIGSL ERREREAAQY PTTRAGEILA 730 740 750 760 770 780 AVPANHVPAP PRLLWADGSN PGELIVQIRT IDRAGLLARL TAVFERDGVD IAWAKVTTLG 790 800 810 820 SSVVDAFGIT TADGRTEQVR QELERDLYAV LPTPPPAKPA EQAS

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000480 Genomic DNA. Translation: ABK73395.1.
RefSeq	YP_886767.1. NC_008596.1.
3D structure databases
ProteinModelPortal	A0QV29.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QV29.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000041543; EBMYCP00000039880; EBMYCG00000041538.
GeneID	4533814.
GenomeReviews	Gene locus MSMEG_2427 in contig CP000480_GR.
KEGG	msm:MSMEG_2427.
NMPDR	fig|246196.1.peg.2426.
PATRIC	18077280. VBIMycSme59918_2392.
TIGR	MSMEG_2427.
Phylogenomic databases
eggNOG	COG2844.
GeneTree	EBGT00050000017408.
HOGENOM	HBG350889.
OMA	LPHTATR.
PhylomeDB	A0QV29.
ProtClustDB	PRK03381.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl_transf. [Tree]
InterPro	IPR002912. ACT-bd. IPR010043. GlnD_Uridyltrans. IPR023279. HD. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Gene3D	G3DSA:1.10.3210.10. HD. 1 hit.
KO	K00990.
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 1 hit. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0QV29_MYCS2

Accession

Primary (citable) accession number: A0QV29

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)