A0QV24 (ACYP_MYCS2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	MSMEG_2422

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	98 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 98	98	Acylphosphatase HAMAP MF_01450		PRO_0000326750
Regions
	Domain	12 – 98	87	Acylphosphatase-like
Sites
	Active site	27	1	By similarity
	Active site	45	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0QV24 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 246B954B8B39D035	FASTA	98	10,756
	10 20 30 40 50 60 MTGPGPRRDE ARLSAWVHGH VQGVGFRWWT RARALELGLT GFASNRPDGR VHVVAQGSRE 70 80 90 ACEKLLELLR SGETPGSVDK VIADWAEPDA TMTGFSER

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000480 Genomic DNA. Translation: ABK73038.1.
RefSeq	YP_886762.1. NC_008596.1.
3D structure databases
ProteinModelPortal	A0QV24.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QV24.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000041005; EBMYCP00000039342; EBMYCG00000041000.
GeneID	4534310.
GenomeReviews	Gene locus MSMEG_2422 in contig CP000480_GR.
KEGG	msm:MSMEG_2422.
NMPDR	fig|246196.1.peg.2421.
PATRIC	18077270. VBIMycSme59918_2387.
TIGR	MSMEG_2422.
Phylogenomic databases
eggNOG	COG1254.
GeneTree	EBGT00050000017282.
HOGENOM	HBG750266.
OMA	GRVCVVA.
PhylomeDB	A0QV24.
Enzyme and pathway databases
BioCyc	MSME246196:MSMEG_2422-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. False negative. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_MYCS2

Accession

Primary (citable) accession number: A0QV24

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program