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Protein
Submitted name:

Hydrolase, NUDIX family protein

Gene

MSMEG_2390

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi65Magnesium 1; via carbonyl oxygenCombined sources1
Metal bindingi81Magnesium 2Combined sources1
Metal bindingi85Magnesium 1Combined sources1
Metal bindingi85Magnesium 2Combined sources1
Metal bindingi127Magnesium 1Combined sources1
Metal bindingi127Magnesium 2Combined sources1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported
LigandMagnesiumCombined sources, Metal-bindingCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Hydrolase, NUDIX family proteinImported
Gene namesi
Ordered Locus Names:MSMEG_2390Imported
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000757 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi246196.MSMEG_2390.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5GG5X-ray1.64A1-322[»]
5GG6X-ray1.75A/B1-322[»]
5GG7X-ray1.70A/B1-322[»]
5GG8X-ray1.85A1-322[»]
5GG9X-ray1.60A1-322[»]
5GGAX-ray1.75A1-322[»]
5GGBX-ray1.10A1-322[»]
5GGCX-ray1.85A/B1-322[»]
5GGDX-ray1.70A/B1-322[»]
ProteinModelPortaliA0QUZ2.
SMRiA0QUZ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 156Nudix hydrolaseInterPro annotationAdd BLAST135

Sequence similaritiesi

Belongs to the Nudix hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108Q1G. Bacteria.
COG0406. LUCA.
COG0494. LUCA.
HOGENOMiHOG000248960.
KOiK03574.
OMAiRYDDWSW.
OrthoDBiPOG091H0B7K.

Family and domain databases

CDDicd07067. HP_PGM_like. 1 hit.
Gene3Di3.40.50.1240. 1 hit.
InterProiView protein in InterPro
IPR013078. His_Pase_superF_clade-1.
IPR029033. His_PPase_superfam.
IPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
PfamiView protein in Pfam
PF00300. His_Phos_1. 1 hit.
PF00293. NUDIX. 1 hit.
PRINTSiPR00502. NUDIXFAMILY.
SMARTiView protein in SMART
SM00855. PGAM. 1 hit.
SUPFAMiSSF53254. SSF53254. 1 hit.
SSF55811. SSF55811. 1 hit.
PROSITEiView protein in PROSITE
PS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.

Sequencei

Sequence statusi: Complete.

A0QUZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMPVDDLQEI PLSKDTTEKS KHTVRAAGAV LWRDASEHGG TTGHPATVEV
60 70 80 90 100
AVIHRPRYDD WSLPKGKLDQ GETEPVAAAR EIHEETGHTA VLGRRLGRVT
110 120 130 140 150
YPIPQGTKRV WYWAAKSTGG DFSPNDEVDK LVWLPVDAAM DQLQYPDDRK
160 170 180 190 200
VLRRFVKRPV DTKTVLVVRH GTAGRRSRYK GDDRKRPLDK RGRAQAEALV
210 220 230 240 250
AQLMAFGATT LYAADRVRCH QTIEPLAQEL DQLIHNEPLL TEEAYAADHK
260 270 280 290 300
AARKRLLEIA GRPGNPVICT QGKVIPGLIE WWCERAKVRP ETTGNRKGST
310 320
WVLSLSDGEL VGADYLSPPD EK
Length:322
Mass (Da):35,923
Last modified:January 9, 2007 - v1
Checksum:iEC7AC99FBF4D351E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK74793.1.
RefSeqiWP_011728311.1. NZ_CP009494.1.
YP_886730.1. NC_008596.1.

Genome annotation databases

EnsemblBacteriaiABK74793; ABK74793; MSMEG_2390.
GeneIDi4536888.
KEGGimsm:MSMEG_2390.
PATRICifig|246196.19.peg.2354.

Similar proteinsi

Entry informationi

Entry nameiA0QUZ2_MYCS2
AccessioniPrimary (citable) accession number: A0QUZ2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: September 27, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported