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A0QTL8 (A0QTL8_MYCS2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
EC=2.5.1.19 HAMAP MF_00210
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210
Gene names
Name:aroA HAMAP MF_00210
Ordered Locus Names:MSMEG_1890
OrganismMycobacterium smegmatis (strain ATCC 700084 / mc(2)155) EMBL ABK72540.1
Taxonomic identifier246196 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length443 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family. HAMAP MF_00210

Sequences

Sequence LengthMass (Da)Tools
A0QTL8 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: 82B1E0B9924F7A9A

FASTA44345,836
        10         20         30         40         50         60 
MSARADEEQK PHWAAPSTTA PVDATVTVPG SKSLTNRALI LAALATSQGT STISGALRSR 

        70         80         90        100        110        120 
DTDLMIEAIR TLGVTVDISA ADPTELTVHG SIEPATDATV DCGLAGTVLR FVPPVAALSR 

       130        140        150        160        170        180 
SSVTFDGDEQ ARSRPIAPLL DGLRRLGVRL DGDGLPFTVR GTGTVSGGTV EIDASGSSQF 

       190        200        210        220        230        240 
VSGLLLSGAG FENGLTIVHT GVSVPSAPHV AMTVAMLRDA GVEVDDSVAN RWQVNPGPVA 

       250        260        270        280        290        300 
ARSWNIEPDL SNSTPFLAAA LVTGGTVRIA GWPTVSIQPA DTILELLATV GGSVREADGH 

       310        320        330        340        350        360 
LEVTGAHEYG GFEADLHDVG ELAPTVAALA ALAKEGSTSQ LRGIAHLRGH ETDRLAALTT 

       370        380        390        400        410        420 
EINGLGGDCR ETDDGLLITA RPLHGGTWRS YADHRMATAG AIVGLRVPGV VVENIETTAK 

       430        440 
TLPDFPSMWV DMLAGEPGRN QQR

« Hide

References

[1]Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000480 Genomic DNA. Translation: ABK72540.1.
RefSeqYP_886256.1. NC_008596.1.

3D structure databases

ProteinModelPortalA0QTL8.
SMRA0QTL8. Positions 13-434.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0QTL8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000040613; EBMYCP00000038950; EBMYCG00000040608.
GeneID4534632.
GenomeReviewsGene locus MSMEG_1890 in contig CP000480_GR.
KEGGmsm:MSMEG_1890.
NMPDRfig|246196.1.peg.1892.
PATRIC18076231. VBIMycSme59918_1872.
TIGRMSMEG_1890.

Phylogenomic databases

eggNOGCOG0128.
GeneTreeEBGT00050000016231.
HOGENOMHBG646626.
OMAHRMATAG.
PhylomeDBA0QTL8.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0QTL8_MYCS2
AccessionPrimary (citable) accession number: A0QTL8
Entry history
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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