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Protein

10 kDa chaperonin

Gene

groS

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-1582-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
10 kDa chaperoninUniRule annotation
Alternative name(s):
GroES proteinUniRule annotation
Protein Cpn10UniRule annotation
Gene namesi
Name:groSUniRule annotation
Synonyms:groESUniRule annotation
Ordered Locus Names:MSMEG_1582, MSMEI_1544
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000006158 Componenti: Chromosome
  • UP000000757 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 1009910 kDa chaperoninPRO_1000025304Add
BLAST

Interactioni

Subunit structurei

Heptamer of 7 subunits arranged in a ring.UniRule annotation

Protein-protein interaction databases

STRINGi246196.MSMEG_1582.

Structurei

3D structure databases

ProteinModelPortaliA0QSS3.
SMRiA0QSS3. Positions 4-100.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GroES chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105K5Y. Bacteria.
COG0234. LUCA.
HOGENOMiHOG000133897.
KOiK04078.
OMAiVMGENEI.
OrthoDBiEOG6GFGSD.

Family and domain databases

Gene3Di2.30.33.40. 1 hit.
HAMAPiMF_00580. CH10.
InterProiIPR020818. Chaperonin_GroES.
IPR018369. Chaprnonin_Cpn10_CS.
IPR011032. GroES-like.
[Graphical view]
PANTHERiPTHR10772. PTHR10772. 1 hit.
PfamiPF00166. Cpn10. 1 hit.
[Graphical view]
PRINTSiPR00297. CHAPERONIN10.
SMARTiSM00883. Cpn10. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
PROSITEiPS00681. CHAPERONINS_CPN10. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A0QSS3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASVNIKPLE DKILVQANEA ETTTASGLVI PDTAKEKPQE GTVVAVGPGR
60 70 80 90 100
WDEDGEKRIP LDVAEGDTVI YSKYGGTEIK YNGEEYLILS ARDVLAVVSK
Length:100
Mass (Da):10,763
Last modified:January 9, 2007 - v1
Checksum:i06537F104C1F9400
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK72614.1.
CP001663 Genomic DNA. Translation: AFP38017.1.
RefSeqiWP_003892970.1. NZ_CP009494.1.
YP_885961.1. NC_008596.1.

Genome annotation databases

EnsemblBacteriaiABK72614; ABK72614; MSMEG_1582.
AFP38017; AFP38017; MSMEI_1544.
GeneIDi4532222.
KEGGimsb:LJ00_07900.
msg:MSMEI_1544.
msm:MSMEG_1582.
PATRICi18075623. VBIMycSme59918_1568.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK72614.1.
CP001663 Genomic DNA. Translation: AFP38017.1.
RefSeqiWP_003892970.1. NZ_CP009494.1.
YP_885961.1. NC_008596.1.

3D structure databases

ProteinModelPortaliA0QSS3.
SMRiA0QSS3. Positions 4-100.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246196.MSMEG_1582.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK72614; ABK72614; MSMEG_1582.
AFP38017; AFP38017; MSMEI_1544.
GeneIDi4532222.
KEGGimsb:LJ00_07900.
msg:MSMEI_1544.
msm:MSMEG_1582.
PATRICi18075623. VBIMycSme59918_1568.

Phylogenomic databases

eggNOGiENOG4105K5Y. Bacteria.
COG0234. LUCA.
HOGENOMiHOG000133897.
KOiK04078.
OMAiVMGENEI.
OrthoDBiEOG6GFGSD.

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-1582-MONOMER.

Family and domain databases

Gene3Di2.30.33.40. 1 hit.
HAMAPiMF_00580. CH10.
InterProiIPR020818. Chaperonin_GroES.
IPR018369. Chaprnonin_Cpn10_CS.
IPR011032. GroES-like.
[Graphical view]
PANTHERiPTHR10772. PTHR10772. 1 hit.
PfamiPF00166. Cpn10. 1 hit.
[Graphical view]
PRINTSiPR00297. CHAPERONIN10.
SMARTiSM00883. Cpn10. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
PROSITEiPS00681. CHAPERONINS_CPN10. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155.
  2. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
    Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.
    Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155.
  3. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
    Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
    Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE.
    Strain: ATCC 700084 / mc(2)155.

Entry informationi

Entry nameiCH10_MYCS2
AccessioniPrimary (citable) accession number: A0QSS3
Secondary accession number(s): I7FYF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: February 17, 2016
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.