A0QSS1 (GCP_MYCS2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	MSMEG_1580

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	340 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 340	340	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303431

Sequences

	Sequence		Length	Mass (Da)
	A0QSS1 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: C434D7218AF0B92F	FASTA	340	34,718
	10 20 30 40 50 60 MIILAIESSC DETGVGIADL RDDGTVTLLA DEVASSVDEH ARFGGVVPEI ASRAHLEALG 70 80 90 100 110 120 PTMRRALDAA GIERPDVVAA TIGPGLAGAL LVGVAAAKAY AAGWGVPFYG VNHLGGHLAA 130 140 150 160 170 180 DVYDHGPLPE SVGLLVSGGH THLLHVRSLG EPIIELGSTV DDAAGEAYDK VARLLGLGYP 190 200 210 220 230 240 GGRVLDELAR TGDRDAIVFP RGMTGPRDDP YTFSFSGLKT AVARYVEAHP EASHADVAAG 250 260 270 280 290 300 FQESVADVLT AKAVRAATDL GVSTLLIAGG VAANSRLREL AEERCAAAGL TLRVPRPRLC 310 320 330 340 TDNGAMIASF AAHLIAAGAQ PSPLDAASDP GLPVVKGQVA

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000480 Genomic DNA. Translation: ABK75193.1.
RefSeq	YP_885959.1. NC_008596.1.
3D structure databases
ProteinModelPortal	A0QSS1.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QSS1.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000044425; EBMYCP00000042762; EBMYCG00000044420.
GeneID	4531302.
GenomeReviews	Gene locus MSMEG_1580 in contig CP000480_GR.
KEGG	msm:MSMEG_1580.
NMPDR	fig|246196.1.peg.1577.
PATRIC	18075619. VBIMycSme59918_1566.
TIGR	MSMEG_1580.
Phylogenomic databases
eggNOG	COG0533.
GeneTree	EBGT00050000017447.
HOGENOM	HBG304663.
OMA	PLYGVNH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	MSME246196:MSMEG_1580-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_MYCS2

Accession

Primary (citable) accession number: A0QSS1

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program