Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A0QSR5

- A0QSR5_MYCS2

UniProt

A0QSR5 - A0QSR5_MYCS2

Protein

Glutamate decarboxylase

Gene

MSMEG_1574

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (09 Jan 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciMSME246196:GJ4Y-1574-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Ordered Locus Names:MSMEG_1574Imported
    OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
    Taxonomic identifieri246196 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000000757: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi246196.MSMEG_1574.

    Structurei

    3D structure databases

    ProteinModelPortaliA0QSR5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    HOGENOMiHOG000070228.
    KOiK01580.
    OMAiAQYYTFL.
    OrthoDBiEOG6TFCPW.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A0QSR5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSHKQSRGPH VAPAYTGRLA MAPVPSLRLP DEAMDPSAAY RFIHDELMLD    50
    GSSRLNLATF VTTWMDPEAE KLMAETFDKN MIDKDEYPAT AAIEARCVSM 100
    VADLFHAEDL RDDDPASAVG VSTIGSSEAV MLAGLAMKWR WRAKAGDWKG 150
    RTPNLVMGAN VQVVWEKFCR YFDVEPRYLP MAEGRYVITP EQVLDAVDED 200
    TIGVVAILGT TYTGELEPVA EICEALDKLA AGGGVDVPVH VDAASGGFVV 250
    PFIHPDLVWD FRLPRVVSIN VSGHKYGLTY PGVGFVVWRN KEHLPEELVF 300
    RVNYLGGDMP TFTLNFSRPG NQVVGQYYNF LRLGRAGYTQ VMQCLSQTAR 350
    WLGDELRDSE HFELISDGSA IPVVAFRLKG DPGYTEFDIS QALRAHGWQV 400
    PAYTMPEGAE DVVVLRVVVR EGFSADLARA LKDDIITVLG QLDALKPRGQ 450
    FDQLQPFAH 459
    Length:459
    Mass (Da):50,768
    Last modified:January 9, 2007 - v1
    Checksum:i1AE0042D24A40797
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000480 Genomic DNA. Translation: ABK75920.1.
    RefSeqiWP_011727746.1. NC_008596.1.
    YP_885953.1. NC_008596.1.

    Genome annotation databases

    EnsemblBacteriaiABK75920; ABK75920; MSMEG_1574.
    GeneIDi4537342.
    KEGGimsm:MSMEG_1574.
    PATRICi18075607. VBIMycSme59918_1560.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000480 Genomic DNA. Translation: ABK75920.1 .
    RefSeqi WP_011727746.1. NC_008596.1.
    YP_885953.1. NC_008596.1.

    3D structure databases

    ProteinModelPortali A0QSR5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 246196.MSMEG_1574.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK75920 ; ABK75920 ; MSMEG_1574 .
    GeneIDi 4537342.
    KEGGi msm:MSMEG_1574.
    PATRICi 18075607. VBIMycSme59918_1560.

    Phylogenomic databases

    eggNOGi COG0076.
    HOGENOMi HOG000070228.
    KOi K01580.
    OMAi AQYYTFL.
    OrthoDBi EOG6TFCPW.

    Enzyme and pathway databases

    BioCyci MSME246196:GJ4Y-1574-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
      Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700084 / mc(2)155Imported.

    Entry informationi

    Entry nameiA0QSR5_MYCS2
    AccessioniPrimary (citable) accession number: A0QSR5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 9, 2007
    Last sequence update: January 9, 2007
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3