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Protein

50S ribosomal protein L6

Gene

rplF

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L6UniRule annotation
Gene namesi
Name:rplFUniRule annotation
Ordered Locus Names:MSMEG_1470, MSMEI_1434
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium fortuitum complex
Proteomesi
  • UP000006158 Componenti: Chromosome
  • UP000000757 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000552661 – 17950S ribosomal protein L6Add BLAST179

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi246196.MSMEG_1470

Structurei

Secondary structure

1179
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni3 – 6Combined sources4
Beta strandi17 – 19Combined sources3
Beta strandi22 – 25Combined sources4
Beta strandi33 – 35Combined sources3
Beta strandi42 – 46Combined sources5
Turni47 – 49Combined sources3
Beta strandi50 – 54Combined sources5
Helixi60 – 81Combined sources22
Beta strandi84 – 90Combined sources7
Beta strandi92 – 96Combined sources5
Beta strandi101 – 103Combined sources3
Beta strandi107 – 112Combined sources6
Beta strandi114 – 116Combined sources3
Beta strandi123 – 128Combined sources6
Beta strandi131 – 137Combined sources7
Helixi139 – 150Combined sources12
Beta strandi157 – 159Combined sources3
Beta strandi162 – 164Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5O60electron microscopy3.20G1-179[»]
5O61electron microscopy3.31G1-179[»]
5XYMelectron microscopy3.08G1-179[»]
ProteinModelPortaliA0QSG4
SMRiA0QSG4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL6 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R5J Bacteria
COG0097 LUCA
HOGENOMiHOG000039903
KOiK02933
OMAiINNMVVG
OrthoDBiPOG091H029Q

Family and domain databases

Gene3Di3.90.930.12, 2 hits
HAMAPiMF_01365_B Ribosomal_L6_B, 1 hit
InterProiView protein in InterPro
IPR000702 Ribosomal_L6
IPR020040 Ribosomal_L6_a/b-dom
IPR036789 Ribosomal_L6_a/b-dom_sf
IPR019906 Ribosomal_L6_bac-type
IPR002358 Ribosomal_L6_CS
PANTHERiPTHR11655 PTHR11655, 1 hit
PTHR11655:SF14 PTHR11655:SF14, 1 hit
PfamiView protein in Pfam
PF00347 Ribosomal_L6, 2 hits
PIRSFiPIRSF002162 Ribosomal_L6, 1 hit
PRINTSiPR00059 RIBOSOMALL6
SUPFAMiSSF56053 SSF56053, 2 hits
TIGRFAMsiTIGR03654 L6_bact, 1 hit
PROSITEiView protein in PROSITE
PS00525 RIBOSOMAL_L6_1, 1 hit

Sequencei

Sequence statusi: Complete.

A0QSG4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRIGKQPVP VPSGVDVTIN GQNLSVKGPK GTLTLDVAEP ISVSRAEDGA
60 70 80 90 100
IVVTRPDDER RSRSLHGLSR TLIANLVTGV TEGYTQKMEI FGVGYRVQLK
110 120 130 140 150
GQNLEFALGY SHPVLIEAPE GITFAVESPT KFSVSGIDKQ KVGQISAVIR
160 170
RLRRPDPYKG KGVRYEGEQI RRKVGKTGK
Length:179
Mass (Da):19,453
Last modified:January 9, 2007 - v1
Checksum:i1668D25BBD493EA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA Translation: ABK73224.1
CP001663 Genomic DNA Translation: AFP37907.1
RefSeqiWP_003892857.1, NZ_CP009494.1
YP_885852.1, NC_008596.1

Genome annotation databases

EnsemblBacteriaiABK73224; ABK73224; MSMEG_1470
AFP37907; AFP37907; MSMEI_1434
GeneIDi4536743
KEGGimsb:LJ00_07345
msg:MSMEI_1434
msm:MSMEG_1470
PATRICifig|246196.19.peg.1455

Similar proteinsi

Entry informationi

Entry nameiRL6_MYCS2
AccessioniPrimary (citable) accession number: A0QSG4
Secondary accession number(s): I7FY99
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health