A0QSG4 (RL6_MYCS2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L6

Gene names

Name:	rplF
Ordered Locus Names:	MSMEG_1470

Organism

Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

Taxonomic identifier

246196 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	179 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center By similarity. HAMAP MF_01365_B
Subunit structure	Part of the 50S ribosomal subunit By similarity. HAMAP MF_01365_B
Sequence similarities	Belongs to the ribosomal protein L6P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 179	179	50S ribosomal protein L6 HAMAP MF_01365_B		PRO_1000055266

Sequences

	Sequence		Length	Mass (Da)
	A0QSG4 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 1668D25BBD493EA5	FASTA	179	19,453
	10 20 30 40 50 60 MSRIGKQPVP VPSGVDVTIN GQNLSVKGPK GTLTLDVAEP ISVSRAEDGA IVVTRPDDER 70 80 90 100 110 120 RSRSLHGLSR TLIANLVTGV TEGYTQKMEI FGVGYRVQLK GQNLEFALGY SHPVLIEAPE 130 140 150 160 170 GITFAVESPT KFSVSGIDKQ KVGQISAVIR RLRRPDPYKG KGVRYEGEQI RRKVGKTGK

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700084 / mc(2)155.
[2]	"Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol." Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O. Genome Res. 19:128-135(2009) [PubMed: 18955433] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000480 Genomic DNA. Translation: ABK73224.1.
RefSeq	YP_885852.1. NC_008596.1.
3D structure databases
ProteinModelPortal	A0QSG4.
SMR	A0QSG4. Positions 8-179.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QSG4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000045745; EBMYCP00000044082; EBMYCG00000045740.
GeneID	4536743.
GenomeReviews	Gene locus MSMEG_1470 in contig CP000480_GR.
KEGG	msm:MSMEG_1470.
NMPDR	fig|246196.1.peg.1467.
PATRIC	18075397. VBIMycSme59918_1455.
TIGR	MSMEG_1470.
Phylogenomic databases
eggNOG	COG0097.
GeneTree	EBGT00050000015590.
HOGENOM	HBG606796.
OMA	ALINNMV.
PhylomeDB	A0QSG4.
ProtClustDB	PRK05498.
Enzyme and pathway databases
BioCyc	MSME246196:MSMEG_1470-MONOMER.
Family and domain databases
HAMAP	MF_01365_B. Ribosomal_L6_B. [Tree]
InterPro	IPR000702. Ribosomal_L6. IPR020040. Ribosomal_L6_a/b-dom. IPR019906. Ribosomal_L6_bac-type. IPR002358. Ribosomal_L6_CS. [Graphical view]
Gene3D	G3DSA:3.90.930.12. Ribosomal_L6. 2 hits.
KO	K02933.
PANTHER	PTHR11655:SF6. PTHR11655:SF6. 1 hit. PTHR11655. Ribosomal_L6. 1 hit.
Pfam	PF00347. Ribosomal_L6. 2 hits. [Graphical view]
PIRSF	PIRSF002162. Ribosomal_L6. 1 hit.
PRINTS	PR00059. RIBOSOMALL6.
SUPFAM	SSF56053. Ribosomal_L6. 2 hits.
TIGRFAMs	TIGR03654. L6_bact. 1 hit.
PROSITE	PS00525. RIBOSOMAL_L6_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL6_MYCS2

Accession

Primary (citable) accession number: A0QSG4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program