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Protein

50S ribosomal protein L11

Gene

rplK

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L11UniRule annotation
Gene namesi
Name:rplKUniRule annotation
Ordered Locus Names:MSMEG_1346, MSMEI_1308
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium fortuitum complex
Proteomesi
  • UP000006158 Componenti: Chromosome
  • UP000000757 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000462201 – 14250S ribosomal protein L11Add BLAST142

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki101Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup)1 Publication

Post-translational modificationi

One or more lysine residues are methylated.UniRule annotation

Keywords - PTMi

Isopeptide bond, Methylation, Ubl conjugation

Interactioni

Subunit structurei

Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.UniRule annotation

Protein-protein interaction databases

STRINGi246196.MSMEG_1346

Structurei

Secondary structure

1142
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi11 – 15Combined sources5
Turni23 – 26Combined sources4
Helixi27 – 31Combined sources5
Turni32 – 34Combined sources3
Helixi37 – 51Combined sources15
Beta strandi56 – 62Combined sources7
Beta strandi68 – 72Combined sources5
Helixi77 – 83Combined sources7
Turni94 – 96Combined sources3
Helixi104 – 117Combined sources14
Helixi123 – 136Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5O60electron microscopy3.20J1-142[»]
5O61electron microscopy3.31J1-142[»]
ProteinModelPortaliA0QS45
SMRiA0QS45
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL11 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UIK Bacteria
COG0080 LUCA
HOGENOMiHOG000082123
KOiK02867
OMAiCKQFNAK
OrthoDBiPOG091H00SK

Family and domain databases

CDDicd00349 Ribosomal_L11, 1 hit
Gene3Di1.10.10.250, 1 hit
3.30.1550.10, 1 hit
HAMAPiMF_00736 Ribosomal_L11, 1 hit
InterProiView protein in InterPro
IPR000911 Ribosomal_L11/L12
IPR036796 Ribosomal_L11/L12_N_sf
IPR006519 Ribosomal_L11_bac-typ
IPR020783 Ribosomal_L11_C
IPR036769 Ribosomal_L11_C_sf
IPR020785 Ribosomal_L11_CS
IPR020784 Ribosomal_L11_N
PANTHERiPTHR11661 PTHR11661, 1 hit
PfamiView protein in Pfam
PF00298 Ribosomal_L11, 1 hit
PF03946 Ribosomal_L11_N, 1 hit
SMARTiView protein in SMART
SM00649 RL11, 1 hit
SUPFAMiSSF46906 SSF46906, 1 hit
SSF54747 SSF54747, 1 hit
TIGRFAMsiTIGR01632 L11_bact, 1 hit
PROSITEiView protein in PROSITE
PS00359 RIBOSOMAL_L11, 1 hit

Sequencei

Sequence statusi: Complete.

A0QS45-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPKKKVAGL IKLQIQAGQA NPAPPVGPAL GQHGVNIMEF CKAYNAATES
60 70 80 90 100
QRGNVIPVEI TVYEDRSFTF ALKTPPAAKL LLKAAGVQKG SGEPHKTKVA
110 120 130 140
KVTWDQVREI AETKKADLNA NDIDAAAKII AGTARSMGIT VE
Length:142
Mass (Da):15,002
Last modified:January 9, 2007 - v1
Checksum:i7DE04CBF2F3C37E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA Translation: ABK76087.1
CP001663 Genomic DNA Translation: AFP37781.1
RefSeqiWP_003892734.1, NZ_CP009494.1
YP_885733.1, NC_008596.1

Genome annotation databases

EnsemblBacteriaiABK76087; ABK76087; MSMEG_1346
AFP37781; AFP37781; MSMEI_1308
GeneIDi4536970
KEGGimsb:LJ00_06710
msg:MSMEI_1308
msm:MSMEG_1346
PATRICifig|246196.19.peg.1330

Similar proteinsi

Entry informationi

Entry nameiRL11_MYCS2
AccessioniPrimary (citable) accession number: A0QS45
Secondary accession number(s): I7G3N3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: May 23, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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