Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

5-oxovalerate dehydrogenase

Gene

MSMEG_1158

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-1158-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
5-oxovalerate dehydrogenaseImported
Submitted name:
Aldehyde dehydrogenaseImported (EC:1.2.1.-Imported)
Gene namesi
Ordered Locus Names:MSMEG_1158Imported, MSMEI_1126Imported
ORF Names:LJ00_05765Imported
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000000757: Chromosome, UP000006158: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi246196.MSMEG_1158.

Structurei

3D structure databases

ProteinModelPortaliA0QRL4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271511.
KOiK00128.
OMAiANTSEYS.
OrthoDBiEOG6BS8QW.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0QRL4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTNAQNLIGG AWVGEPIIER RNPANPDDVV AIAPSASAAD VHDAVAAATD
60 70 80 90 100
AQPGWAALTA VQRGAILMDA ADLLRRRHEE IATDLTREEG KTRAEAMGEV
110 120 130 140 150
RRAIDVLRFF GSAGWRPSGE TLPSTMPNTS VHTRREPLGV VGLVTPWNFP
160 170 180 190 200
IAIPAWKMAP ALVSGNAVVI KPAELTPLSI NHLATALIDA GLPAGVLNVV
210 220 230 240 250
HGSGSLAGDA LVRHQEVAAV SFTGSTGVGM AIRDVVNARN ARVQLEMGGK
260 270 280 290 300
NAYLVLDDAD VEAAAATVAA GAFSLTGQAC TATSRVYVTP GVREVFVKAL
310 320 330 340 350
REKAGAVKSG NGLDPGTTMG PVVSDAQLAK DVTAIHAAVE AGFDAGEVTE
360 370 380 390 400
PKGQFLAPVV FSGVPHDHPL VTREVFGPVV GVIDVADYQE GLNLVNDSPY
410 420 430 440 450
GLTAGICTRD LGKAYDFAAR VRVGVVKINR PTTGLDLNVP FGGVRDSSTN
460 470
TFREQGERAV DFYTWTKSVY IGHDL
Length:475
Mass (Da):49,696
Last modified:January 9, 2007 - v1
Checksum:iEB02CBB8BDEAB5A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK71275.1.
CP001663 Genomic DNA. Translation: AFP37604.1.
CP009494 Genomic DNA. Translation: AIU06406.1.
RefSeqiWP_011727459.1. NC_018289.1.
YP_006565899.1. NC_018289.1.
YP_885552.1. NC_008596.1.

Genome annotation databases

EnsemblBacteriaiABK71275; ABK71275; MSMEG_1158.
AFP37604; AFP37604; MSMEI_1126.
GeneIDi4537648.
KEGGimsm:MSMEG_1158.
PATRICi18074781. VBIMycSme59918_1151.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK71275.1.
CP001663 Genomic DNA. Translation: AFP37604.1.
CP009494 Genomic DNA. Translation: AIU06406.1.
RefSeqiWP_011727459.1. NC_018289.1.
YP_006565899.1. NC_018289.1.
YP_885552.1. NC_008596.1.

3D structure databases

ProteinModelPortaliA0QRL4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246196.MSMEG_1158.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK71275; ABK71275; MSMEG_1158.
AFP37604; AFP37604; MSMEI_1126.
GeneIDi4537648.
KEGGimsm:MSMEG_1158.
PATRICi18074781. VBIMycSme59918_1151.

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271511.
KOiK00128.
OMAiANTSEYS.
OrthoDBiEOG6BS8QW.

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-1158-MONOMER.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.
  2. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  3. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
    Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.
    Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  4. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
    Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
    Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155 and MC2 155.
  5. "Complete Genome Sequence of Mycobacterium smegmatis Laboratory Strains (INHwt) and Isoniazid Resistant (INHR1/R2) Mutant Strains."
    Mohan A., Padiadpu J., Baloni P., Chandra N.
    Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.

Entry informationi

Entry nameiA0QRL4_MYCS2
AccessioniPrimary (citable) accession number: A0QRL4
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: February 4, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.