Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

GDP-mannose-dependent alpha-mannosyltransferase

Gene

mgtA

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the addition of a mannose residue from GDP-D-mannose to GlcAGroAc2 to generate 1,2-di-O-C16/C18:1-(alpha-D-mannopyranosyl)-1-4-(alpha-D-glucopyranosyluronic acid)-1-3-glycerol(ManGlcAGroAc2).By similarity

Pathwayi: phosphatidylinositol metabolism

This protein is involved in the pathway phosphatidylinositol metabolism, which is part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the pathway phosphatidylinositol metabolism and in Phospholipid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism, Virulence

Enzyme and pathway databases

BioCyciMSME246196:G1H7P-1117-MONOMER
UniPathwayiUPA00949

Protein family/group databases

CAZyiGT4 Glycosyltransferase Family 4

Names & Taxonomyi

Protein namesi
Recommended name:
GDP-mannose-dependent alpha-mannosyltransferase (EC:2.4.1.-)
Alternative name(s):
Guanosine diphosphomannose-dependent alpha-mannosyltransferase
Gene namesi
Name:mgtA
Synonyms:pimB
Ordered Locus Names:MSMEG_1113, MSMEI_1080
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium fortuitum complex
Proteomesi
  • UP000006158 Componenti: Chromosome
  • UP000000757 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003937311 – 375GDP-mannose-dependent alpha-mannosyltransferaseAdd BLAST375

Proteomic databases

PRIDEiA0QRG8

Interactioni

Protein-protein interaction databases

STRINGi246196.MSMEG_1113

Structurei

3D structure databases

ProteinModelPortaliA0QRG8
SMRiA0QRG8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0438 LUCA
HOGENOMiHOG000077285
KOiK12583
OMAiWQRGVDT
OrthoDBiPOG091H079K

Family and domain databases

InterProiView protein in InterPro
IPR001296 Glyco_trans_1
IPR028098 Glyco_trans_4-like_N
PfamiView protein in Pfam
PF13439 Glyco_transf_4, 1 hit
PF00534 Glycos_transf_1, 1 hit

Sequencei

Sequence statusi: Complete.

A0QRG8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVAIVAESF LPNVNGVTNS VLRVIDHLRR TGHEVLVIAP DTPRGQPPAD
60 70 80 90 100
RIHDGVRVHR VPSRMFPKIT SLPLGVPRPR MIGVLRGFDP DVVHLASPAL
110 120 130 140 150
LGYGGLHAAR HLGVPSVAVF QTDVAGFAES YGMGVASRAA WAWTRHLHSR
160 170 180 190 200
ADRTLAPSTS AMENLAAHRI PRVHRWGRGV DITGFVPSAR DEHLRRTWSP
210 220 230 240 250
DGRPIVGFVG RLAPEKHVER LAVLAARDDL QLVIVGDGVD RVKLQTVLPT
260 270 280 290 300
AVFTGELRGA ALAAAYASMD VFVHPGEHET FCQTVQEAMA SGVPVIAPDA
310 320 330 340 350
GGPRDLVAPC RTGLLLDVDG FECALPAAVT HLIAERRRYG IAARRSVLAR
360 370
TWPVVCDELI GHYEAVLGRR SLRAA
Length:375
Mass (Da):40,565
Last modified:January 9, 2007 - v1
Checksum:i62410854271FD7C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA Translation: ABK71357.1
CP001663 Genomic DNA Translation: AFP37560.1
RefSeqiWP_011727419.1, NZ_CP009494.1
YP_885506.1, NC_008596.1

Genome annotation databases

EnsemblBacteriaiABK71357; ABK71357; MSMEG_1113
AFP37560; AFP37560; MSMEI_1080
GeneIDi4534281
KEGGimsb:LJ00_05530
msg:MSMEI_1080
msm:MSMEG_1113
PATRICifig|246196.19.peg.1101

Similar proteinsi

Entry informationi

Entry nameiMGTA_MYCS2
AccessioniPrimary (citable) accession number: A0QRG8
Secondary accession number(s): I7F7L0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: January 9, 2007
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health