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Protein
Submitted name:

Mycobacterium smegmatis str. MC2 155, complete genome

Gene

pknK

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-529-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Mycobacterium smegmatis str. MC2 155, complete genomeImported
Submitted name:
Probable serine/threonine-protein kinase PknKImported (EC:2.7.11.1Imported)
Submitted name:
Serine/threonine-protein kinase transcriptional regulatory protein PknKImported (EC:2.7.11.1Imported)
Gene namesi
Name:pknKImported
Ordered Locus Names:MSMEG_0529Imported, MSMEI_0514Imported
ORF Names:LJ00_02620Imported
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000006158 Componenti: Chromosome UP000000757 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi246196.MSMEG_0529.

Structurei

3D structure databases

ProteinModelPortaliA0QPV2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000074403.
KOiK13419.
OMAiRANVENE.
OrthoDBiEOG69GZGV.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0QPV2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRNDPLPTQ RDLPAGIPAE LVAAGFEDPD EIGRGGFGVV YRCVQRALDR
60 70 80 90 100
TVAVKVLTTD LEPDNLERFM REQVAMGKLS GHPNIVNIFQ VGTIASGRPY
110 120 130 140 150
IVMQYHPHGS LSAKIQAAGP LGWRGALRIG VKMAGALETA HQRDTLHRDV
160 170 180 190 200
KPANILLTEY GEPQLTDFGI ARIAGGFETA EGAIMGSPAY TAPEVLLGES
210 220 230 240 250
PTVASDVYSL ASTVFTASTG HAVFERGKGE QMVAQFLRIT RHPAPNLRDA
260 270 280 290 300
DLPADLSAAI EQAMSRTISD RPESAQAFGE QLRELQRRHG LPVDDMPIPI
310 320 330 340 350
APPTDRPSSI ASPTPSSGYP VRTLTPPAPA TRFQMPSSAK RLVERARLID
360 370 380 390 400
VLRAQRDKKL TVIHGPTGFG KSTLAVQWAK QLAADGVAVA WLTVDDDDNN
410 420 430 440 450
VVWFLSHVIE AIRSVMPALA SDLGDVLEEH GDDAERYVLT SLINDIHSSG
460 470 480 490 500
RRMTLVIDDW HRVTDPATIA ALRYLLDNVA SGLTVVVTSR TQSGLPMSRM
510 520 530 540 550
RMQGEIVEID ATALRFDVSE SGSFLVDLAG LDLDQTDVEE LTEKTDGWVA
560 570 580 590 600
ALQLASLTLR DRDDPVQLIE TMTGRHHVIS EFLAENVLET LEPSTLDFLL
610 620 630 640 650
ATSIPERICG GLASALTDVP DGQAILEKIE ERDLFLRRID DQWFRYHQLF
660 670 680 690 700
RDFLRHRLSR ERVCDLHRRA CRWYAGQRLV REAVDHALAA GDETEAVRLV
710 720 730 740 750
ENDGLYLVSG GQMATLIGLT AKLPQDIVRS NPRLQLALAW ANIVLHRVPA
760 770 780 790 800
ARDALARVEA TMADAGLSED EIADMRAEAD VVRAIADLRS DRLSGIDEHV
810 820 830 840 850
AACLQRRDRM PPFSVATAAT VATFAAAYRY DLDEVERIQT WAAPYYERSG
860 870 880 890 900
DAFSIVNGLC FCGIAHHLML NNAVAEQTLR RALRIAKRSG GIHSYAGRLA
910 920 930 940 950
SSLLGEILYE KGDLAEAERL LDEGYKLGPE GGSVDFKIAR YVISARIKAL
960 970 980 990 1000
QGDRLGAAQR LDEATRVARS LSLNRLQALA EHERIRLGLP PHPEFGPMPV
1010 1020 1030 1040 1050
VSYDARREPV DAMDAIALQF EEASAIRRLM ASDDPAARDL ACRWAREWVD
1060 1070 1080 1090 1100
RLSALNRPQA LLRARRLLGA CLAADGRTAE AKAMVATVAA QCAQLRMLRY
1110 1120 1130 1140
LVDGGPQVVA TLVELRADQE AGRWSPEWPE VPADFLQDAI NSVAPQRY
Length:1,148
Mass (Da):125,995
Last modified:January 9, 2007 - v1
Checksum:iB9A70F6523EAC95F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK71316.1.
CP001663 Genomic DNA. Translation: AFP36995.1.
CP009494 Genomic DNA. Translation: AIU05799.1.
RefSeqiWP_011727014.1. NC_018289.1.
YP_006565290.1. NC_018289.1.
YP_884940.1. NC_008596.1.

Genome annotation databases

EnsemblBacteriaiABK71316; ABK71316; MSMEG_0529.
AFP36995; AFP36995; MSMEI_0514.
AIU05799; AIU05799; LJ00_02620.
GeneIDi4532549.
KEGGimsm:MSMEG_0529.
PATRICi18073528. VBIMycSme59918_0526.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK71316.1.
CP001663 Genomic DNA. Translation: AFP36995.1.
CP009494 Genomic DNA. Translation: AIU05799.1.
RefSeqiWP_011727014.1. NC_018289.1.
YP_006565290.1. NC_018289.1.
YP_884940.1. NC_008596.1.

3D structure databases

ProteinModelPortaliA0QPV2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246196.MSMEG_0529.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK71316; ABK71316; MSMEG_0529.
AFP36995; AFP36995; MSMEI_0514.
AIU05799; AIU05799; LJ00_02620.
GeneIDi4532549.
KEGGimsm:MSMEG_0529.
PATRICi18073528. VBIMycSme59918_0526.

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000074403.
KOiK13419.
OMAiRANVENE.
OrthoDBiEOG69GZGV.

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-529-MONOMER.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.
  2. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  3. "Interrupted coding sequences in Mycobacterium smegmatis: authentic mutations or sequencing errors?"
    Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C., Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.
    Genome Biol. 8:R20.1-R20.9(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155Imported and MC2 155Imported.
  4. "Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol."
    Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M., Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.
    Genome Res. 19:128-135(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700084 / mc(2)155 and MC2 155.
  5. "Complete Genome Sequences of a Mycobacterium smegmatis Laboratory Strain (MC2 155) and Isoniazid-Resistant (4XR1/R2) Mutant Strains."
    Mohan A., Padiadpu J., Baloni P., Chandra N.
    Genome Announc. 3:0-0(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MC2 155Imported.

Entry informationi

Entry nameiA0QPV2_MYCS2
AccessioniPrimary (citable) accession number: A0QPV2
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: May 27, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.