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Protein
Submitted name:

Transcriptional regulator, LacI family

Gene

MSMEG_0491

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei147 – 1471Acetate 1Combined sources
Binding sitei195 – 1951Acetate 1Combined sources
Binding sitei220 – 2201Acetate 1Combined sources
Binding sitei251 – 2511Acetate 1Combined sources
Binding sitei260 – 2601Acetate 2Combined sources
Binding sitei279 – 2791Acetate 1Combined sources
Binding sitei288 – 2881Acetate 3; via amide nitrogen and carbonyl oxygenCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-491-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Transcriptional regulator, LacI familyImported
Submitted name:
Transcriptional regulator, LacI family proteinImported
Gene namesi
Ordered Locus Names:MSMEG_0491Imported, MSMEI_0478Imported
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Imported
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000006158 Componenti: Chromosome
  • UP000000757 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi246196.MSMEG_0491.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3KKEX-ray2.20A/B/C/D50-341[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 5857HTH lacI-type DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains HTH lacI-type DNA-binding domain.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105ETE. Bacteria.
COG1609. LUCA.
HOGENOMiHOG000220179.
KOiK02529.
OrthoDBiPOG091H01VT.

Family and domain databases

CDDicd01392. HTH_LacI. 1 hit.
Gene3Di1.10.260.40. 1 hit.
InterProiIPR000843. HTH_LacI.
IPR010982. Lambda_DNA-bd_dom.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00356. LacI. 1 hit.
[Graphical view]
SMARTiSM00354. HTH_LACI. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF53822. SSF53822. 1 hit.
PROSITEiPS50932. HTH_LACI_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0QPR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTLADVARA AGVSVSIASR ALSGDTRARM SEATRARVLA AADELNYVPN
60 70 80 90 100
ARARALRHSR SGTIGLIVPD VNNAVFADMF SGVQMAASGH STDVLLGQID
110 120 130 140 150
APPRGTQQLS RLVSEGRVDG VLLQRREDFD DDMLAAVLEG VPAVTINSRV
160 170 180 190 200
PGRVGSVILD DQKGGGIATE HLITLGHSRI AFISGTAIHD TAQRRKEGYL
210 220 230 240 250
ETLASAGLRS EAAWVVDAGW EADAGSAALN TLYRGANLGK PDGPTAVVVA
260 270 280 290 300
SVNAAVGALS TALRLGLRVP EDLSIVGINT TWVSDTVYPA LTTVRLPLQR
310 320 330 340
LGEVAADVLM EHLGGRALTD TVVTQPTPEL LVRETTAPPT RD
Length:342
Mass (Da):35,759
Last modified:January 9, 2007 - v1
Checksum:i9805CAF2D930C513
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK70082.1.
CP001663 Genomic DNA. Translation: AFP36959.1.
RefSeqiWP_011726990.1. NZ_CP009494.1.
YP_884904.1. NC_008596.1.

Genome annotation databases

EnsemblBacteriaiABK70082; ABK70082; MSMEG_0491.
AFP36959; AFP36959; MSMEI_0478.
GeneIDi4531255.
KEGGimsb:LJ00_02430.
msg:MSMEI_0478.
msm:MSMEG_0491.
PATRICi18073446. VBIMycSme59918_0485.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA. Translation: ABK70082.1.
CP001663 Genomic DNA. Translation: AFP36959.1.
RefSeqiWP_011726990.1. NZ_CP009494.1.
YP_884904.1. NC_008596.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3KKEX-ray2.20A/B/C/D50-341[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246196.MSMEG_0491.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK70082; ABK70082; MSMEG_0491.
AFP36959; AFP36959; MSMEI_0478.
GeneIDi4531255.
KEGGimsb:LJ00_02430.
msg:MSMEI_0478.
msm:MSMEG_0491.
PATRICi18073446. VBIMycSme59918_0485.

Phylogenomic databases

eggNOGiENOG4105ETE. Bacteria.
COG1609. LUCA.
HOGENOMiHOG000220179.
KOiK02529.
OrthoDBiPOG091H01VT.

Enzyme and pathway databases

BioCyciMSME246196:GJ4Y-491-MONOMER.

Family and domain databases

CDDicd01392. HTH_LacI. 1 hit.
Gene3Di1.10.260.40. 1 hit.
InterProiIPR000843. HTH_LacI.
IPR010982. Lambda_DNA-bd_dom.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00356. LacI. 1 hit.
[Graphical view]
SMARTiSM00354. HTH_LACI. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF53822. SSF53822. 1 hit.
PROSITEiPS50932. HTH_LACI_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA0QPR6_MYCS2
AccessioniPrimary (citable) accession number: A0QPR6
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: September 7, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.