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A0QKS0

- A0QKS0_MYCA1

UniProt

A0QKS0 - A0QKS0_MYCA1

Protein

Glutamate decarboxylase

Gene

MAV_4373

Organism
Mycobacterium avium (strain 104)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (09 Jan 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Enzyme and pathway databases

    BioCyciMAVI243243:GH3Y-4373-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Ordered Locus Names:MAV_4373Imported
    OrganismiMycobacterium avium (strain 104)Imported
    Taxonomic identifieri243243 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)
    ProteomesiUP000001574: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi243243.MAV_4373.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    HOGENOMiHOG000070228.
    KOiK01580.
    OMAiAQYYTFL.
    OrthoDBiEOG6TFCPW.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A0QKS0-1 [UniParc]FASTAAdd to Basket

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    MPQHPSLPAH AIAPAYTGRL FTAPVPALRM PDESMDPDAA YRFIHDELML    50
    DGSSRLNLAT FVTTWMDPEA GRLMAETFDK NMIDKDEYPA TAAIEQRCVC 100
    MVADLFHAEG LNDADPYSAC GVSTIGSSEA VMLGGLAMKW RWRAKTKDWK 150
    KRTPNLVMGS NVQVVWEKFC RYFDVEPRYL PMEEGRYVIT PEQVVDAVDE 200
    DTIGVVAILG TTYTGELEPV ADICGALDKL AARGGVDVPV HVDAASGGFV 250
    VPFLHPELKW DFRLPRVVSI NVSGHKYGLT YPGVGFVVWR SKEYLPDELV 300
    FRVNYLGGDM PTFTLNFSRP GNQVVGQYYN FLRLGREGYT KVMQTLSGTA 350
    RWLGEQLRVS EHCELISDGS AIPVVAFRLA KDRGYTEFDV SHELRTYGWQ 400
    VPAYTMPDNA TDVSVLRIVV REGLSADLAR ALHDDAVSAL TSLDKVKPGG 450
    HYDAQHFAH 459
    Length:459
    Mass (Da):50,991
    Last modified:January 9, 2007 - v1
    Checksum:i5CEC5F0DCF4C980E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000479 Genomic DNA. Translation: ABK67541.1.
    RefSeqiYP_883508.1. NC_008595.1.

    Genome annotation databases

    EnsemblBacteriaiABK67541; ABK67541; MAV_4373.
    GeneIDi4529217.
    KEGGimav:MAV_4373.
    PATRICi17990445. VBIMycAvi38287_4296.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000479 Genomic DNA. Translation: ABK67541.1 .
    RefSeqi YP_883508.1. NC_008595.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243243.MAV_4373.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK67541 ; ABK67541 ; MAV_4373 .
    GeneIDi 4529217.
    KEGGi mav:MAV_4373.
    PATRICi 17990445. VBIMycAvi38287_4296.

    Phylogenomic databases

    eggNOGi COG0076.
    HOGENOMi HOG000070228.
    KOi K01580.
    OMAi AQYYTFL.
    OrthoDBi EOG6TFCPW.

    Enzyme and pathway databases

    BioCyci MAVI243243:GH3Y-4373-MONOMER.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
      Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 104Imported.

    Entry informationi

    Entry nameiA0QKS0_MYCA1
    AccessioniPrimary (citable) accession number: A0QKS0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 9, 2007
    Last sequence update: January 9, 2007
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3