A0QKR4 (GCP_MYCA1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	MAV_4367

Organism

Mycobacterium avium (strain 104) [Complete proteome] [HAMAP]

Taxonomic identifier

243243 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303428

Sequences

	Sequence		Length	Mass (Da)
	A0QKR4 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 69F1711F7308373C	FASTA	341	34,723
	10 20 30 40 50 60 MTTILAIETS CDETGVGIAR LDADGAVTLL ADEVASSVDE HVRFGGVVPE IASRAHLEAL 70 80 90 100 110 120 GPTMRRALSA AGVTKPDVVA ATIGPGLAGA LLVGVAAAKA YSAAWGVPFY AVNHLGGHLA 130 140 150 160 170 180 ADVYQHGPLP ECVALLVSGG HTHLLQVRSL GDPIVELGST VDDAAGEAYD KVARLLGLGY 190 200 210 220 230 240 PGGRVLDELA RTGDREAIVF PRGMTGPRDA PYAFSFSGLK TAVARYLESH PDAVNADVAA 250 260 270 280 290 300 GFQEAVADVL TRKAVRAATD LGVTTLLIAG GVAANSRLRE LAEQRCAAAG LTLRIPRPGL 310 320 330 340 CTDNGAMIAS FAAHLVAAGA PPSPLDVPTD PGLPVVKAQV S

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 104.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000479 Genomic DNA. Translation: ABK67578.1.
RefSeq	YP_883502.1. NC_008595.1.
3D structure databases
ProteinModelPortal	A0QKR4.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QKR4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000011505; EBMYCP00000011391; EBMYCG00000011503.
GeneID	4525654.
GenomeReviews	Gene locus MAV_4367 in contig CP000479_GR.
KEGG	mav:MAV_4367.
PATRIC	17990433. VBIMycAvi38287_4290.
TIGR	MAV_4367.
Phylogenomic databases
eggNOG	COG0533.
GeneTree	EBGT00050000017447.
HOGENOM	HBG304663.
OMA	PLYGVNH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	MAVI243243:MAV_4367-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_MYCA1

Accession

Primary (citable) accession number: A0QKR4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program