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Protein

Riboflavin biosynthesis protein

Gene

ribF

Organism
Mycobacterium avium (strain 104)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + FMN = diphosphate + FAD.UniRule annotation
ATP + riboflavin = ADP + FMN.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. FMN adenylyltransferase activity Source: UniProtKB-EC
  2. riboflavin kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. riboflavin biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, NucleotidyltransferaseUniRule annotationImported, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, FADUniRule annotation, Flavoprotein, FMNUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMAVI243243:GH3Y-3678-MONOMER.
UniPathwayiUPA00276; UER00406.
UPA00277; UER00407.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin biosynthesis proteinUniRule annotation (EC:2.7.1.26UniRule annotation, EC:2.7.7.2UniRule annotation)
Gene namesi
Name:ribFImported
Ordered Locus Names:MAV_3678Imported
OrganismiMycobacterium avium (strain 104)Imported
Taxonomic identifieri243243 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)
ProteomesiUP000001574: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi243243.MAV_3678.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0196.
HOGENOMiHOG000006844.
KOiK11753.
OMAiFHFGRGR.
OrthoDBiEOG6QP0ZV.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
3.40.50.620. 1 hit.
InterProiIPR015864. FAD_synthase.
IPR023468. Riboflavin_kinase.
IPR002606. Riboflavin_kinase_bac.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF06574. FAD_syn. 1 hit.
PF01687. Flavokinase. 1 hit.
[Graphical view]
PIRSFiPIRSF004491. FAD_Synth. 1 hit.
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 1 hit.
TIGRFAMsiTIGR00083. ribF. 1 hit.

Sequencei

Sequence statusi: Complete.

A0QIW7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTIGVFDGV HRGHAELIAH AVKAGRARNV PTVLMTFDPH PMEVVYPGSH
60 70 80 90 100
PAQLTTLTRR AELVEELGID VFLVMPFTTD FMKLTPDRYV HELLVENLHV
110 120 130 140 150
VEVVVGENFT FGKKATGNVE TLRRAGERFG FAVEAMSLLS EHHSNQTVTF
160 170 180 190 200
SSTYIRSCVD AGDVVAAMEA LGRPHRVEGV VVRGEGRGIQ LGFPTANVAP
210 220 230 240 250
PMYSAIPADG VYAAWFTVLG HGPVTGTVIP GERYQAAVSV GTNPTFSGRT
260 270 280 290 300
RTVEAFVLDT QADLYGQHVA LDFVARIRGQ HKFDSVDDLV VAMGQDTERA

RQLLSAG
Length:307
Mass (Da):33,322
Last modified:January 9, 2007 - v1
Checksum:iD78635C328DD2FB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000479 Genomic DNA. Translation: ABK67639.1.
RefSeqiWP_003878662.1. NC_008595.1.
YP_882855.1. NC_008595.1.

Genome annotation databases

EnsemblBacteriaiABK67639; ABK67639; MAV_3678.
GeneIDi4526223.
KEGGimav:MAV_3678.
PATRICi17989038. VBIMycAvi38287_3599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000479 Genomic DNA. Translation: ABK67639.1.
RefSeqiWP_003878662.1. NC_008595.1.
YP_882855.1. NC_008595.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243243.MAV_3678.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK67639; ABK67639; MAV_3678.
GeneIDi4526223.
KEGGimav:MAV_3678.
PATRICi17989038. VBIMycAvi38287_3599.

Phylogenomic databases

eggNOGiCOG0196.
HOGENOMiHOG000006844.
KOiK11753.
OMAiFHFGRGR.
OrthoDBiEOG6QP0ZV.

Enzyme and pathway databases

UniPathwayiUPA00276; UER00406.
UPA00277; UER00407.
BioCyciMAVI243243:GH3Y-3678-MONOMER.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
3.40.50.620. 1 hit.
InterProiIPR015864. FAD_synthase.
IPR023468. Riboflavin_kinase.
IPR002606. Riboflavin_kinase_bac.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF06574. FAD_syn. 1 hit.
PF01687. Flavokinase. 1 hit.
[Graphical view]
PIRSFiPIRSF004491. FAD_Synth. 1 hit.
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 1 hit.
TIGRFAMsiTIGR00083. ribF. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
    Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 104Imported.

Entry informationi

Entry nameiA0QIW7_MYCA1
AccessioniPrimary (citable) accession number: A0QIW7
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: March 4, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.