A0QIW2 (A0QIW2_MYCA1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183

Gene names

Name:	ald EMBL ABK65745.1
Ordered Locus Names:	MAV_3674

Organism

Mycobacterium avium (strain 104) [Complete proteome] [HAMAP]

Taxonomic identifier

243243 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	373 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183
Pathway	Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000183
Molecular function	Oxidoreductase PIRNR PIRNR000183 EMBL ABK65745.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alanine dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QIW2 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: D195BA296BAB127A	FASTA	373	38,979
	10 20 30 40 50 60 MRVGVPTETK TNEFRVALTP AGVAELTRRG HEVLVQSGAG EGSSIPDSEF KAAGAQLADT 70 80 90 100 110 120 AEQVWADAEL LLKVKEPVPA EYDLLRRNQI LFTFLHLAAS RACTEALLSS GTTSIAYETV 130 140 150 160 170 180 QTADGTLPLL APMSEVAGRL SAQVGAYHLM RTHGGRGVLM GGVPGVKPAD VVVVGAGTAG 190 200 210 220 230 240 YNAARVAGGM GAMVTVLDVN INKLRLLDAE FDGQVRTRYS SAYDLEGTVK RADLVIGAVL 250 260 270 280 290 300 LPGAKAPNLI SNSLVAQMKS GAVLVDISID QGGCFEDSRP TTHDDPTFAV HDTVFYCVAN 310 320 330 340 350 360 MPSAVPKTST VALTNATMPY VLALADRGWR AACRSDHALA KGLSTHDGTL LSQQVAADLG 370 LPCTDPAGVL QQD

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000479 Genomic DNA. Translation: ABK65745.1.
RefSeq	YP_882850.1. NC_008595.1.
3D structure databases
ProteinModelPortal	A0QIW2.
SMR	A0QIW2. Positions 1-370.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QIW2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000010019; EBMYCP00000009905; EBMYCG00000010017.
GeneID	4530716.
GenomeReviews	Gene locus MAV_3674 in contig CP000479_GR.
KEGG	mav:MAV_3674.
PATRIC	17989026. VBIMycAvi38287_3593.
TIGR	MAV_3674.
Phylogenomic databases
eggNOG	COG0686.
GeneTree	EBGT00050000016024.
HOGENOM	HBG289735.
OMA	VAHGHEV.
ProtClustDB	CLSK792072.
Family and domain databases
InterPro	IPR008142. Ala_DH/PNT_CS1. IPR008143. Ala_DH/PNT_CS2. IPR008141. Ala_DH/Pyr_transHydgase. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. [Graphical view]
KO	K00259.
PANTHER	PTHR10160:SF3. PTHR10160:SF3. 1 hit.
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000183. Alanine_dh. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00518. AlaDH. 1 hit.
PROSITE	PS00836. ALADH_PNT_1. 1 hit. PS00837. ALADH_PNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0QIW2_MYCA1

Accession

Primary (citable) accession number: A0QIW2

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)