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A0QHY0 (CAPP_MYCA1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:MAV_3336
OrganismMycobacterium avium (strain 104) [Complete proteome] [HAMAP]
Taxonomic identifier243243 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)

Protein attributes

Sequence length935 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 935935Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_1000025565

Sites

Active site1611 By similarity
Active site5931 By similarity

Sequences

Sequence LengthMass (Da)Tools
A0QHY0 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: DF4E7779B3A41F2B

FASTA935102,548
        10         20         30         40         50         60 
MVEASEGTLE PIGAVQRTLV GREATEPMRA DIGLLGAILG DTVREQNGQQ VFELVERARV 

        70         80         90        100        110        120 
ESFRVRRSEI DRAELARMFA GIDIHQAIPV IRAFSHFALL ANVAEDIHRE RRRAIHVAAG 

       130        140        150        160        170        180 
EPPQDSSLAA TYAKLDRAQL DSATVAEALR GAVVSPVITA HPTETRRRTV FVTQHRITEL 

       190        200        210        220        230        240 
MRLHAEGHIE TDDGRNIELE LRRQVLTLWQ TALIRLSRLQ ITDEIEVGLR YYAAAFFKVI 

       250        260        270        280        290        300 
PRVNAEVRNA LRARWPGADL LDEPIVAPGS WIGGDRDGNP NVTADVVRRA TGDAAYTALA 

       310        320        330        340        350        360 
HYLAELTACE QELSMSARLV AVTPELAALA EDCAEKARAD EPYRRALRVI RGRLTATAAE 

       370        380        390        400        410        420 
ILDRRPQHEL DLGLPPYATP AELRGDLDTV DASLRAHGSA LLADDRLALL REGVRVFGFH 

       430        440        450        460        470        480 
LCGLDMRQNS DVHEEVVAEL LAWAGVHPDY RSLPEDERVE LLAAELGTRR PLVGDRAELS 

       490        500        510        520        530        540 
ELADKELGVV RAAAHAIRRY GPAAVPNYVI SMCRSVSDVL EAAILLKEAG LIDASGPEPY 

       550        560        570        580        590        600 
CPVGISPLFE TIEDLHNGAA ILHAMLELPL YRALVAARGQ SQEVMLGYSD SNKDGGYLAS 

       610        620        630        640        650        660 
SWAVYRAELA LVEVARKTGI RLRLFHGRGG TVGRGGGPSY EAILAQPPGA VNGSLRLTEQ 

       670        680        690        700        710        720 
GEVIAAKYAE PQVAQRNLES LVAATLESTL LDVEGLGDTA EPAYAVLDEV AVLAQRAYAE 

       730        740        750        760        770        780 
LVHETPGFVD YFMASTPVSE IGSLNIGSRP TSRKPTESIA DLRAIPWVLA WSQSRVMLPG 

       790        800        810        820        830        840 
WYGTGSAFEQ WIAAGPQSRA ERVDILHDLY RRWPFFRSVL SNLAQVLAKS DLGLAAQYAE 

       850        860        870        880        890        900 
LVDDAALRRR VFGKIADEHR RTIAMHKLIT GQDNLLADNP ALARSVFNRF PYLEPLNHLQ 

       910        920        930 
VELLRRYRSG DDDELVQRGI LLTMNGLTSA LRNSG 

« Hide

References

[1]Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 104.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000479 Genomic DNA. Translation: ABK67960.1.
RefSeqYP_882518.1. NC_008595.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243243.MAV_3336.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK67960; ABK67960; MAV_3336.
GeneID4526911.
KEGGmav:MAV_3336.
PATRIC17988359. VBIMycAvi38287_3264.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238647.
KOK01595.
OMAAIPWVFG.
OrthoDBEOG6TJ7T8.
ProtClustDBPRK00009.

Enzyme and pathway databases

BioCycMAVI243243:GH3Y-3336-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_MYCA1
AccessionPrimary (citable) accession number: A0QHY0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: February 19, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families