A0QHL8 (A0QHL8_MYCA1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III alpha subunit EMBL ABK65317.1
EC=2.7.7.7 EMBL ABK65317.1

Gene names

Ordered Locus Names:

MAV_3224

Organism

Mycobacterium avium (strain 104) [Complete proteome] [HAMAP]

Taxonomic identifier

243243 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	1177 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Cellular component	Cytoplasm SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QHL8 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 8372D32326B6D064	FASTA	1,177	128,867
	10 20 30 40 50 60 MNHSSFVHLH NHTEYSMLDG AAKITPMLAE VERLGMPAVG MTDHGNMFGA SEFYNAATKA 70 80 90 100 110 120 GIKPIIGVEA YIAPGSRFDT RRILWGDPSQ KADDVSGSGS YTHLTMVAEN AAGLRNLFKL 130 140 150 160 170 180 SSLASFEGQL GKWSRMDAEL IAEHADGIIA TTGCPSGEVQ TRLRLGQDRE ALESAAKWRE 190 200 210 220 230 240 IFGADNFFLE LMDHGLSIEQ RVRGGLLEIG RKLNIPPLAT NDCHYVTRDA AHNHEALLCV 250 260 270 280 290 300 QTGKTLSDPN RFKFDGDGYY LKSAAEMRQI WDAEVPGACD STLLIAERVQ SYAEVWTPRD 310 320 330 340 350 360 RMPVFPVPEG HDQASWLHHE VMAGLRRRFP DGVGQDYIDR AEYEIKVICD KGFPSYFLIV 370 380 390 400 410 420 ADLINYARSV DIRVGPGRGS AAGSLVAYAL GITNIDPIPH GLLFERFLNP ERPSAPDIDI 430 440 450 460 470 480 DFDDRRRGEM VRYAADKWGS DRVAQVITFG TIKTKAALKD SARIHYGQPG FAIADRITKA 490 500 510 520 530 540 LPPPIMAKDI PLSGITDPSH ERYKEAAEVR GLIETDPDVR TIYQTARGLE GLIRNAGVHA 550 560 570 580 590 600 CAVIMSSEPL TEAIPLWKRP QDGAIITGWD YPSCEAIGLL KMDFLGLRNL TIIGDALDNI 610 620 630 640 650 660 KANRGIDLDL ESVPLDDKAT YELLGRGDTL GVFQLDGGPM RDLLRRMQPT EFNDIVAVLA 670 680 690 700 710 720 LYRPGPMGMN AHNDYADRKN GRQPIKPIHP ELEEPLREIL AETYGLIVYQ EQIMFIAQKV 730 740 750 760 770 780 ASYTMGKADA LRKAMGKKKL EVLEAEYKGF YEGMTANGFS EKAVKALWDT ILPFAGYAFN 790 800 810 820 830 840 KSHAAGYGLV SYWTAYLKAN YPAEYMAGLL TSVGDDKDKA AVYLADCRKL GITVLPPDVN 850 860 870 880 890 900 ESLVNFASVG QDIRFGLGAV RNVGANVVGS LIKTREEKGK FTDFSDYLNK IDISACNKKV 910 920 930 940 950 960 TESLIKAGAF DSLKHARKGL FLVHTDAVDS VLGTKKAEAM GQFDLFGGDG GCTESVFTIK 970 980 990 1000 1010 1020 VPDDEWEDKH KLALEREMLG LYVSGHPLNG VAHLLAAQVD TQIPAILDGD VPNETQVRVG 1030 1040 1050 1060 1070 1080 GILASVNRRV NKNGMPWASA QLEDLTGGIE VMFFPHAYST YGADIADDAV VLINAKVAIR 1090 1100 1110 1120 1130 1140 DDRIALIANE LVVPDFSIAQ VDRPLAVSLP TRQCTIDKVT ALKQVLARHP GTSQVHLRLI 1150 1160 1170 SGDRITTLEL DASLRVTPSP ALMGDLKELL GPGCLGG

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000479 Genomic DNA. Translation: ABK65317.1.
RefSeq	YP_882406.1. NC_008595.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A0QHL8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000011177; EBMYCP00000011063; EBMYCG00000011175.
GeneID	4529658.
GenomeReviews	Gene locus MAV_3224 in contig CP000479_GR.
KEGG	mav:MAV_3224.
PATRIC	17988143. VBIMycAvi38287_3156.
TIGR	MAV_3224.
Phylogenomic databases
eggNOG	COG0587.
GeneTree	EBGT00050000016568.
HOGENOM	HBG734490.
OMA	RVLQMPY.
ProtClustDB	PRK05673.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0QHL8_MYCA1

Accession

Primary (citable) accession number: A0QHL8

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)