A0QH60 (KCY_MYCA1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Name:	cmk
Ordered Locus Names:	MAV_3064

Organism

Mycobacterium avium (strain 104) [Complete proteome] [HAMAP]

Taxonomic identifier

243243 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity HAMAP MF_00238.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 228	228	Cytidylate kinase HAMAP MF_00238		PRO_1000048233
Regions
	Nucleotide binding	11 – 19	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A0QH60 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 26BC72629434F2DB	FASTA	228	24,178
	10 20 30 40 50 60 MSADVVVAID GPAGTGKSSV SKGLARALGA RYLDTGGMYR MVTLAVLRAG IDPADADAVG 70 80 90 100 110 120 RAAQAVRMSV DYHPDGDRYF LGGEDVSTEI RGDKVTAAVS AVSSIPAVRT RLVGLQREMA 130 140 150 160 170 180 SGPGSIVVEG RDIGTVVLPD APVKIFLTAS AETRARRRND QNVAAGLADD YEAVLAEVRR 190 200 210 220 RDHLDSTRRV SPLRAAPDAV VVDTSDMTEA QVIDHLRDLV RQRSEVAR

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 104.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000479 Genomic DNA. Translation: ABK68125.1.
RefSeq	YP_882248.1. NC_008595.1.
3D structure databases
ProteinModelPortal	A0QH60.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QH60.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000012573; EBMYCP00000012459; EBMYCG00000012571.
GeneID	4527937.
GenomeReviews	Gene locus MAV_3064 in contig CP000479_GR.
KEGG	mav:MAV_3064.
PATRIC	17987821. VBIMycAvi38287_2996.
TIGR	MAV_3064.
Phylogenomic databases
eggNOG	COG0283.
GeneTree	EBGT00050000015811.
HOGENOM	HBG354377.
OMA	DIGTVIC.
PhylomeDB	A0QH60.
ProtClustDB	PRK00023.
Enzyme and pathway databases
BioCyc	MAVI243243:MAV_3064-MONOMER.
Family and domain databases
HAMAP	MF_00238. Cytidyl_kinase_type1. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_MYCA1

Accession

Primary (citable) accession number: A0QH60

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 9, 2007
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program