A0QFM5 (A0QFM5_MYCA1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Methylmalonate-semialdehyde dehydrogenase EMBL ABK64568.1
EC=1.2.1.27 EMBL ABK64568.1

Gene names

Name:	mmsA EMBL ABK64568.1
Ordered Locus Names:	MAV_2521

Organism

Mycobacterium avium (strain 104) [Complete proteome] [HAMAP]

Taxonomic identifier

243243 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	509 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344 EMBL ABK64568.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	methylmalonate-semialdehyde dehydrogenase (acylating) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QFM5 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 64BBB6D83A54B077	FASTA	509	54,037
	10 20 30 40 50 60 MTAHTTLIPH FIDGRRSAGQ SGRSADVFDP STGGVQATVP MAGQADIDAA VASAVEAQKG 70 80 90 100 110 120 WAATNPQRRA RVMMRFVELV NEHNDELAEL LSREHGKTLA DAKGDIQRGI EVIEFCVGIP 130 140 150 160 170 180 HLLKGEYSEG AGPGIDVYSL RQPLGVVAGI TPFNFPAMIP LWKAGPALAC GNAFVLKPSE 190 200 210 220 230 240 RDPSVPVRLA ELFVEAGLPP GVFQVVHGDK EAVDAILNHP DIQAVGFVGS SDIAQYIYAG 250 260 270 280 290 300 AAATGKRAQC FGGAKNHMIV MPDADLDQAV DALIGAGYGS AGERCMAISV AVPVGDQTAD 310 320 330 340 350 360 RLRARLIERV NNLRVGHSLD PKADYGPLVT EAALARVRDY IAQGVDAGAE LVIDGRERAS 370 380 390 400 410 420 DDLAFGDANL EGGFFIGPTL FDHVTPDMSI YTDEIFGPVL CIVRAHDYEE ALALPSQHEY 430 440 450 460 470 480 GNGVAVFTGD GDAARDFVSR VQVGMVGVNV PIPVPVAYHT FGGWKRSGFG DLNQHGPASI 490 500 TFYTKTKTVT QRWPSGIKDG AEFSIPTMI

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000479 Genomic DNA. Translation: ABK64568.1.
RefSeq	YP_881713.1. NC_008595.1.
3D structure databases
ProteinModelPortal	A0QFM5.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QFM5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000012512; EBMYCP00000012398; EBMYCG00000012510.
GeneID	4525927.
GenomeReviews	Gene locus MAV_2521 in contig CP000479_GR.
KEGG	mav:MAV_2521.
PATRIC	17986746. VBIMycAvi38287_2460.
TIGR	MAV_2521.
Phylogenomic databases
eggNOG	COG1012.
GeneTree	EBGT00050000015660.
HOGENOM	HBG752218.
OMA	SFRFYTK.
ProtClustDB	CLSK790714.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR010061. MeMal-semiAld_DH. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00140.
PANTHER	PTHR11699:SF27. MMSDH. 1 hit.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01722. MMSDH. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0QFM5_MYCA1

Accession

Primary (citable) accession number: A0QFM5

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)