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Protein

Glutamate racemase

Gene

murI

Organism
Mycobacterium avium (strain 104)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Provides the (R)-glutamate required for cell wall biosynthesis.UniRule annotation

Catalytic activityi

L-glutamate = D-glutamate.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei75Proton donor/acceptorUniRule annotation1
Active sitei185Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processCell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis

Enzyme and pathway databases

UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate racemaseUniRule annotation (EC:5.1.1.3UniRule annotation)
Gene namesi
Name:murIUniRule annotation
Ordered Locus Names:MAV_1555
OrganismiMycobacterium avium (strain 104)
Taxonomic identifieri243243 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)
Proteomesi
  • UP000001574 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000475831 – 275Glutamate racemaseAdd BLAST275

Structurei

3D structure databases

ProteinModelPortaliA0QD02
SMRiA0QD02
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni12 – 13Substrate bindingUniRule annotation2
Regioni44 – 45Substrate bindingUniRule annotation2
Regioni76 – 77Substrate bindingUniRule annotation2
Regioni186 – 187Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the aspartate/glutamate racemases family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000262396
KOiK01776
OMAiVYGCTHY

Family and domain databases

HAMAPiMF_00258 Glu_racemase, 1 hit
InterProiView protein in InterPro
IPR015942 Asp/Glu/hydantoin_racemase
IPR001920 Asp/Glu_race
IPR018187 Asp/Glu_racemase_AS_1
IPR033134 Asp/Glu_racemase_AS_2
IPR004391 Glu_race
PANTHERiPTHR21198:SF2 PTHR21198:SF2, 1 hit
PfamiView protein in Pfam
PF01177 Asp_Glu_race, 1 hit
SUPFAMiSSF53681 SSF53681, 2 hits
TIGRFAMsiTIGR00067 glut_race, 1 hit
PROSITEiView protein in PROSITE
PS00923 ASP_GLU_RACEMASE_1, 1 hit
PS00924 ASP_GLU_RACEMASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0QD02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSALAPVGI FDSGVGGLTV ARAIIDQLPD EHIIYVGDTG HGPYGPLSIP
60 70 80 90 100
EVRAHALAIG DDLVGRGVKA LVIACNTASA ACLRDARERY EVPVVEVILP
110 120 130 140 150
AVRRAVATTR NGRIGVIGTQ ATINSHAYQD AFAAARDTEI TAVACPRFVD
160 170 180 190 200
FVERGVTSGR QVLGLAEGYL EPLQRAQVDT LVLGCTHYPL LSGLIQLAMG
210 220 230 240 250
DNVTLVSSAE ETAKEVLRVL TERDLLHPHP DDPRAAGPSR VFEATGDPEA
260 270
FTRLAARFLG PAVSGVRPVH HVRID
Length:275
Mass (Da):29,144
Last modified:January 9, 2007 - v1
Checksum:i00C6E29DFA035A1A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000479 Genomic DNA Translation: ABK67897.1
RefSeqiWP_009975745.1, NC_008595.1

Genome annotation databases

EnsemblBacteriaiABK67897; ABK67897; MAV_1555
KEGGimav:MAV_1555

Similar proteinsi

Entry informationi

Entry nameiMURI_MYCA1
AccessioniPrimary (citable) accession number: A0QD02
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: March 28, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health