A0QD02 (MURI_MYCA1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	MAV_1555

Organism

Mycobacterium avium (strain 104) [Complete proteome] [HAMAP]

Taxonomic identifier

243243 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	275 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 275	275	Glutamate racemase HAMAP MF_00258		PRO_1000047583

Sequences

	Sequence		Length	Mass (Da)
	A0QD02 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 00C6E29DFA035A1A	FASTA	275	29,144
	10 20 30 40 50 60 MSSALAPVGI FDSGVGGLTV ARAIIDQLPD EHIIYVGDTG HGPYGPLSIP EVRAHALAIG 70 80 90 100 110 120 DDLVGRGVKA LVIACNTASA ACLRDARERY EVPVVEVILP AVRRAVATTR NGRIGVIGTQ 130 140 150 160 170 180 ATINSHAYQD AFAAARDTEI TAVACPRFVD FVERGVTSGR QVLGLAEGYL EPLQRAQVDT 190 200 210 220 230 240 LVLGCTHYPL LSGLIQLAMG DNVTLVSSAE ETAKEVLRVL TERDLLHPHP DDPRAAGPSR 250 260 270 VFEATGDPEA FTRLAARFLG PAVSGVRPVH HVRID

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 104.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000479 Genomic DNA. Translation: ABK67897.1.
RefSeq	YP_880790.1. NC_008595.1.
3D structure databases
ProteinModelPortal	A0QD02.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QD02.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000010268; EBMYCP00000010154; EBMYCG00000010266.
GeneID	4527447.
GenomeReviews	Gene locus MAV_1555 in contig CP000479_GR.
KEGG	mav:MAV_1555.
PATRIC	17984841. VBIMycAvi38287_1518.
TIGR	MAV_1555.
Phylogenomic databases
eggNOG	COG0796.
GeneTree	EBGT00050000016063.
HOGENOM	HBG645102.
OMA	PQEDTIY.
PhylomeDB	A0QD02.
ProtClustDB	PRK00865.
Enzyme and pathway databases
BioCyc	MAVI243243:MAV_1555-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_MYCA1

Accession

Primary (citable) accession number: A0QD02

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program