A0QCD8 (A0QCD8_MYCA1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
1-pyrroline-5-carboxylate dehydrogenase EMBL ABK64504.1
EC=1.5.1.12 EMBL ABK64504.1

Gene names

Name:	pruA EMBL ABK64504.1
Ordered Locus Names:	MAV_1331

Organism

Mycobacterium avium (strain 104) [Complete proteome] [HAMAP]

Taxonomic identifier

243243 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium avium complex (MAC)

Protein attributes

Sequence length	555 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344 EMBL ABK64504.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proline biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrial matrix Inferred from electronic annotation. Source: InterPro
Molecular function	1-pyrroline-5-carboxylate dehydrogenase activity Inferred from electronic annotation. Source: EC oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A0QCD8 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 610BD3A3C0776516	FASTA	555	59,797
	10 20 30 40 50 60 MAAARILGSM DAITGISEVP VPANEPVHDY APHSAERARL RAELAALAGH PIDLPHVIGG 70 80 90 100 110 120 RHRMGDGERI DVVQPHRHAA KLGTLTNAVH ADATAAVDAA MAAKSDWAAM PFDERAAVFL 130 140 150 160 170 180 RAADLLAGPW REKIAAATML GQSKSAYQAE IDSPCEQIDF WRFNVAFARQ ILAQQPISGP 190 200 210 220 230 240 GEWNRSDYRP LDGFVYAITP FNFTSIAGNL PTAPALMGNT VVWKPSITQT LSAYLTMQLL 250 260 270 280 290 300 EAAGLPPGVI NLVTGDGFAV SDVALADRRL AGIHFTGSTA TFQRLWYQVG TNIGHYHCYP 310 320 330 340 350 360 RLVGETGGKD FIVAHASARP DVLRTALIRG AFDYQGQKCS AASRAFIAQS VWRRMGDEFL 370 380 390 400 410 420 AETAALRYGD VTDLTNFGGA LIDRRAFVKN VDAIERAKGA PHVTLAVGGE YDDSEGYFVR 430 440 450 460 470 480 PTVLLSDDPA DESFATEYFG PLLSVHVYPD DDYQRILDVV DTGSRYALTG AVIADDRAAV 490 500 510 520 530 540 LAAQDRLRFA AGNFYVNDKP TGAVVGRQPF GGSRGSGTND KAGSPLNLLR WTSARTIKET 550 FVPATDHTYP HMGAD

References

[1]	Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C., Fraser C.M. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000479 Genomic DNA. Translation: ABK64504.1.
RefSeq	YP_880576.1. NC_008595.1.
3D structure databases
ProteinModelPortal	A0QCD8.
ModBase	Search...
Protein-protein interaction databases
STRING	A0QCD8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000009748; EBMYCP00000009634; EBMYCG00000009746.
GeneID	4529638.
GenomeReviews	Gene locus MAV_1331 in contig CP000479_GR.
KEGG	mav:MAV_1331.
PATRIC	17984403. VBIMycAvi38287_1303.
TIGR	MAV_1331.
Phylogenomic databases
eggNOG	COG1012.
GeneTree	EBGT00050000015660.
HOGENOM	HBG752218.
OMA	CELVDFW.
PhylomeDB	A0QCD8.
ProtClustDB	CLSK871904.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR005931. Delta1-pyrroline-5-COlate_DH-1. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00294.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01236. D1pyr5carbox1. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0QCD8_MYCA1

Accession

Primary (citable) accession number: A0QCD8

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)